Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation

• Published in: Developmental biology Vol. 344; no. 2; pp. 1071 - 1087
• Main Authors: Chiu, Han Sheng, Szucsik, John C., Georgas, Kylie M., Jones, Julia L., Rumballe, Bree A., Tang, Dave, Grimmond, Sean M., Lewis, Alfor G., Aronow, Bruce J., Lessard, James L., Little, Melissa H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.08.2010
• Subjects: Androgens - genetics; Animals; Appendage development; Cell Differentiation - genetics; Embryo, Mammalian; Epidermis; Extremities; Gene Expression; Gene Regulatory Networks; Genital tubercle development; Genitalia, Male - embryology; Lower urinary tract development; Male; Mice; Organogenesis - genetics; Urethra - embryology; Urogenital System - embryology; Wnt; Appendage development; Genital tubercle development; Gene expression; Wnt; Lower urinary tract development

Here we describe the first detailed catalog of gene expression in the developing lower urinary tract (LUT), including epithelial and mesenchymal portions of the developing bladder, urogenital sinus, urethra, and genital tubercle (GT) at E13 and E14. Top compartment-specific genes implicated by the m...