The effect of probiotics on faecal microbiota and genotoxic activity of faecal water in patients with atopic dermatitis: A randomized, placebo-controlled study

• Published in: Clinical nutrition (Edinburgh, Scotland) Vol. 31; no. 1; pp. 22 - 29
• Main Authors: Roessler, A., Forssten, S.D., Glei, M., Ouwehand, A.C., Jahreis, G.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.02.2012; Elsevier
• Subjects: administration & dosage; Adolescent; Adult; adults; Allergic diseases; Atopic dermatitis; beverages; Bifidobacterium; Bifidobacterium - metabolism; Bifidobacterium animalis; Biological and medical sciences; biosynthesis; Clostridium perfringens; colorectal neoplasms; Comet Assay; Comet Assay - methods; Cross-Over Studies; Dermatitis, Atopic; Dermatitis, Atopic - genetics; Dermatitis, Atopic - microbiology; DNA Damage; DNA Primers; DNA Primers - genetics; Double-Blind Method; etiology; fatty acid composition; Fatty Acids, Volatile; Fatty Acids, Volatile - biosynthesis; Feces; Feces - microbiology; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; gas chromatography; Gastroenterology and Hepatology; gel electrophoresis; genetics; Genotoxicity; Humans; Immunopathology; Lactobacillus; Lactobacillus acidophilus; Lactobacillus acidophilus - metabolism; Lactobacillus paracasei; Male; Medical sciences; metabolism; Metagenome; methods; microbiology; Microbiota; patients; physiology; placebos; Probiotic; probiotics; Probiotics - administration & dosage; Real-Time Polymerase Chain Reaction; Skin allergic diseases. Stinging insect allergies; tail; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Water; Water - physiology; Young Adult; Probiotic; SCORAD; Microbiota; Bifidobacterium; AD; Atopic dermatitis; TI; Genotoxicity; qPCR; SCFA; Lactobacillus; tail intensity; scoring of atopic dermatitis; short-chain fatty acids; quantitative real-time polymerase chain reaction; Water; Human; Allergy; Immunopathology; Skin disease; Randomization; Activity; Metabolic diseases; Feces; Atopy

Colonic microbiota is involved in the etiology of colon cancer according to several reports. Studies also indicate that the microbiota differs between atopic patients and healthy subjects. To evaluate whether a probiotic mix containing Lactobacillus paracasei Lpc-37, Lactobacillus acidophilus 74-2,...