Multidimensional Plasma Lipids Affect Preeclampsia/Eclampsia: A Mendelian Randomization Study

• Published in: The journal of clinical hypertension (Greenwich, Conn.) Vol. 27; no. 1; pp. e14939 - n/a
• Main Authors: Shi, Shaole, Wu, Fangyuan, Zhao, Shanshan, Wang, Zilian, Fan, Yongqiang
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.01.2025; John Wiley and Sons Inc; Wiley
• Subjects: Adult; Eclampsia; Eclampsia - blood; Eclampsia - epidemiology; Eclampsia - genetics; Female; Finland - epidemiology; Humans; Lipidomics - methods; Lipids; Lipids - blood; Mendelian randomization; Mendelian Randomization Analysis - methods; Original; Plasma; plasma lipids; Pre-Eclampsia - blood; Pre-Eclampsia - epidemiology; Pre-Eclampsia - genetics; Preeclampsia; Pregnancy; Risk Factors; Triglycerides - blood; Finland; eclampsia; Mendelian randomization; preeclampsia; plasma lipids

ABSTRACT Circulating lipids play a crucial role during pregnancy and may impact various pregnancy‐related diseases. This study employed a two‐sample Mendelian randomization (MR) framework to investigate the causal relationship between alterations in multidimensional plasma lipid levels and the risk...