The Effect of Magnesium Supplementation on Vascular Calcification in CKD: A Randomized Clinical Trial (MAGiCAL-CKD)

• Published in: Journal of the American Society of Nephrology Vol. 34; no. 5; pp. 886 - 894
• Main Authors: Bressendorff, Iain, Hansen, Ditte, Schou, Morten, Kragelund, Charlotte, Svensson, My, Hashemi, Bahram, Kristensen, Tilde, Vrist, Marie Houmaa, Borg, Rikke, Tougaard, Birgitte, Borg, Kristine, Hjortkjær, Henrik Øder, Kristiansen, Cathrine Helgestad, Carlson, Nicholas, Nasiri, Mohammad, Ashraf, Haseem, Pasch, Andreas, Brandi, Lisbet
• Format: Journal Article
• Language: English
• Published: United States American Society of Nephrology 01.05.2023
• Subjects: Chronic Kidney Disease; Clinical Research; Coronary Artery Disease - prevention & control; Dietary Supplements; Humans; Magnesium; Renal Insufficiency, Chronic - therapy; Vascular Calcification - prevention & control; clinical trial; cardiovascular disease; coronary calcification; vascular calcification; magnesium; randomized controlled trials; CKD

Significance StatementMagnesium prevents vascular calcification in animals with CKD. In addition, lower serum magnesium is associated with higher risk of cardiovascular events in CKD. In a randomized, double-blinded, placebo-controlled trial, the authors investigated the effects of magnesium supplem...