Rapid gastric and intestinal transit is a major determinant of changes in blood glucose, intestinal hormones, glucose absorption and postprandial symptoms after gastric bypass

• Published in: Obesity (Silver Spring, Md.) Vol. 22; no. 9; pp. 2003 - 2009
• Main Authors: Nguyen, Nam Q., Debreceni, Tamara L., Bambrick, Jenna E., Bellon, Max, Wishart, Judith, Standfield, Scott, Rayner, Chris K., Horowitz, Michael
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.09.2014
• Subjects: Adult; Blood Glucose - metabolism; Diabetes; Dumping Syndrome - etiology; Dumping Syndrome - metabolism; Dumping Syndrome - physiopathology; Endoscopy; Female; Gastric Bypass - adverse effects; Gastric Bypass - rehabilitation; Gastrointestinal Hormones - blood; Gastrointestinal Transit - physiology; Glucose; Glucose - pharmacokinetics; Humans; Insulin; Insulin - blood; Intestinal Absorption; Male; Middle Aged; Plasma; Postprandial Period; Small intestine; Sulfur; Time Factors

Objective To evaluate the effect of modulating pouch emptying (PE) and SI transit of glucose after Roux‐en‐Y gastric bypass (RYGB) on blood glucose, incretin hormones, glucose absorption and gastrointestinal (GI) symptoms. Methods Ten RYGB patients were studied twice in random order, receiving eithe...