Application of Causal Forest Model to Examine Treatment Effect Heterogeneity in Substance Use Disorder Psychosocial Treatments

• Published in: International journal of methods in psychiatric research Vol. 34; no. 1; pp. e70011 - n/a
• Main Authors: Susukida, Ryoko, Amin‐Esmaeili, Masoumeh, Badillo‐Goicoechea, Elena, Nguyen, Trang Q., Stuart, Elizabeth A., Rosenblum, Michael, Dunn, Kelly E., Mojtabai, Ramin
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.03.2025; John Wiley and Sons Inc; Wiley
• Subjects: Abstinence; Adult; causal forest; Clinical trials; Drug abuse; Drug addiction; Drug use; Female; Forests; heterogeneity; Humans; Male; Models, Statistical; Original; Outcome Assessment, Health Care; Patients; Psychosocial Intervention - methods; psychosocial interventions; Randomized Controlled Trials as Topic; Substance abuse treatment; Substance use; Substance use disorder; substance use disorder treatment; Substance-Related Disorders - therapy; Toxicology; treatment effect; Treatment Effect Heterogeneity; Urine; substance use disorder treatment; treatment effect; causal forest; psychosocial interventions; heterogeneity

ABSTRACT Objectives Heterogeneity of treatment effect (HTE) is a concern in substance use disorder (SUD) treatments but has not been rigorously examined. This exploratory study applied a causal forest approach to examine HTE in psychosocial SUD treatments, considering multiple covariates simultaneou...