Incentive-elicited striatal activation in adolescent children of alcoholics
ABSTRACT Aims Deficient recruitment of motivational circuitry by non‐drug rewards has been postulated as a pre‐morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non‐dr...
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| Published in | Addiction (Abingdon, England) Vol. 103; no. 8; pp. 1308 - 1319 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford, UK
Blackwell Publishing Ltd
01.08.2008
Blackwell |
| Subjects | |
| Online Access | Get full text |
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| Abstract | ABSTRACT
Aims Deficient recruitment of motivational circuitry by non‐drug rewards has been postulated as a pre‐morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non‐drug rewards in adolescence.
Design During functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12–16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing $0, $0.20, $1, $5 or a variable amount (ranging from $0.20 to $5).
Results In general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender‐matched controls. Cue‐elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Losses activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non‐reward) correlated positively with both Brief Sensation‐Seeking Scale scores and with self‐reported excitement in response to maximum reward cues (relative to cues for non‐reward).
Conclusions Among adolescents with no psychiatric disorders, incentive‐elicited VS activation may relate more to individual differences in sensation‐seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors. |
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| AbstractList | Aims Deficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non-drug rewards in adolescence. Design During functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12-16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing $0, $0.20, $1, $5 or a variable amount (ranging from $0.20 to $5). Results In general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender-matched controls. Cue-elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Lossers activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non-reward) correlated positively with both Brief Sensation-Seeking Scale scores and with self-reported excitement in response to maximum reward cues (relative to cues for non-reward). Conclusions Among adolescents with no psychiatric disorders, incentive-elicited VS activation may relate more to individual differences in sensation-seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors. Reprinted by permission of Blackwell Publishing ABSTRACT Aims Deficient recruitment of motivational circuitry by non‐drug rewards has been postulated as a pre‐morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non‐drug rewards in adolescence. Design During functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12–16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing $0, $0.20, $1, $5 or a variable amount (ranging from $0.20 to $5). Results In general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender‐matched controls. Cue‐elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Losses activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non‐reward) correlated positively with both Brief Sensation‐Seeking Scale scores and with self‐reported excitement in response to maximum reward cues (relative to cues for non‐reward). Conclusions Among adolescents with no psychiatric disorders, incentive‐elicited VS activation may relate more to individual differences in sensation‐seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors. Deficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non-drug rewards in adolescence. During functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12-16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing $0, $0.20, $1, $5 or a variable amount (ranging from $0.20 to $5). In general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender-matched controls. Cue-elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Losses activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non-reward) correlated positively with both Brief Sensation-Seeking Scale scores and with self-reported excitement in response to maximum reward cues (relative to cues for non-reward). Among adolescents with no psychiatric disorders, incentive-elicited VS activation may relate more to individual differences in sensation-seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors. Aims Deficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non-drug rewards in adolescence. Design During functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12 -16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing$0,$0.20,$1,$5 or a variable amount (ranging from$0.20 to$5). Results In general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender-matched controls. Cue-elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Losses activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non-reward) correlated positively with both Brief Sensation-Seeking Scale scores and with self-reported excitement in response to maximum reward cues (relative to cues for non-reward). Conclusions Among adolescents with no psychiatric disorders, incentive-elicited VS activation may relate more to individual differences in sensation-seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors. Submitted 5 September 2007; initial review completed 5 February 2008; final version accepted 26 March 2008. Adapted from the source document. Aims: Deficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non-drug rewards in adolescence. Design: During functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12-16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing $0, $0.20, $1, $5 or a variable amount (ranging from $0.20 to $5). Results: In general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender-matched controls. Cue-elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Losses activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non-reward) correlated positively with both Brief Sensation-Seeking Scale scores and with self-reported excitement in response to maximum reward cues (relative to cues for non-reward). Conclusions: Among adolescents with no psychiatric disorders, incentive-elicited VS activation may relate more to individual differences in sensation-seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors. [PUBLICATION ABSTRACT] Aims Deficient recruitment of motivational circuitry by non‐drug rewards has been postulated as a pre‐morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non‐drug rewards in adolescence. Design During functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12–16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing $0, $0.20, $1, $5 or a variable amount (ranging from $0.20 to $5). Results In general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender‐matched controls. Cue‐elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Losses activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non‐reward) correlated positively with both Brief Sensation‐Seeking Scale scores and with self‐reported excitement in response to maximum reward cues (relative to cues for non‐reward). Conclusions Among adolescents with no psychiatric disorders, incentive‐elicited VS activation may relate more to individual differences in sensation‐seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors. Deficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non-drug rewards in adolescence.AIMSDeficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non-drug rewards in adolescence.During functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12-16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing $0, $0.20, $1, $5 or a variable amount (ranging from $0.20 to $5).DESIGNDuring functional magnetic resonance imaging, adolescent children of alcoholics (COA; age 12-16 years) with no psychiatric disorders (including substance abuse) and similarly aged children with no risk factors responded to targets to win or avoid losing $0, $0.20, $1, $5 or a variable amount (ranging from $0.20 to $5).In general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender-matched controls. Cue-elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Losses activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non-reward) correlated positively with both Brief Sensation-Seeking Scale scores and with self-reported excitement in response to maximum reward cues (relative to cues for non-reward).RESULTSIn general, brain activation by either reward anticipation or outcome notification did not differ between COA and age/gender-matched controls. Cue-elicited reward anticipation activated portions of VS in both COA and controls. In nucleus accumbens (NAcc), signal change increased with anticipated reward magnitude (with intermediate recruitment by variable incentives) but not with loss magnitudes. Reward deliveries activated the NAcc and mesofrontal cortex in both COA and controls. Losses activated anterior insula bilaterally in both groups, with more extensive right anterior insula activation by losses in controls. NAcc signal change during anticipation of maximum rewards (relative to non-reward) correlated positively with both Brief Sensation-Seeking Scale scores and with self-reported excitement in response to maximum reward cues (relative to cues for non-reward).Among adolescents with no psychiatric disorders, incentive-elicited VS activation may relate more to individual differences in sensation-seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors.CONCLUSIONSAmong adolescents with no psychiatric disorders, incentive-elicited VS activation may relate more to individual differences in sensation-seeking personality than to presence of parental alcoholism alone. Future research could focus on adolescents with behavior disorders or additional risk factors. |
| Author | Hommer, Daniel W. Knutson, Brian Bjork, James M. |
| Author_xml | – sequence: 1 givenname: James M. surname: Bjork fullname: Bjork, James M. email: jbjork@mail.nih.gov organization: Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA – sequence: 2 givenname: Brian surname: Knutson fullname: Knutson, Brian organization: and Department of Psychology, Stanford University, Palo Alto, CA, USA – sequence: 3 givenname: Daniel W. surname: Hommer fullname: Hommer, Daniel W. organization: Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA |
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| Cites_doi | 10.1152/jn.2000.84.6.3072 10.1037/0021-843X.107.3.363 10.1192/bjp.170.6.541 10.1097/00004583-199712000-00023 10.1523/JNEUROSCI.2431-05.2005 10.1093/alcalc/37.6.522 10.1006/cbmr.1996.0014 10.1016/j.biopsych.2006.04.042 10.1523/JNEUROSCI.1062-06.2006 10.1016/S0191-8869(01)00032-0 10.1002/cne.10627 10.1097/01.wco.0000173463.24758.f6 10.1093/alcalc/37.4.383 10.1002/1096-8628(20001009)96:5<684::AID-AJMG16>3.0.CO;2-G 10.1196/annals.1376.019 10.1542/peds.2006-1221 10.1111/j.1530-0277.2007.00605.x 10.1542/peds.103.S2.1085 10.1523/JNEUROSCI.22-24-10829.2002 10.1016/S0306-4603(98)00038-0 10.1523/JNEUROSCI.0642-05.2005 10.1097/00004583-200001000-00017 10.15288/jsa.1998.59.485 10.1073/pnas.92.13.5880 10.1007/0-306-47148-5_10 10.1037/1064-1297.8.3.264 10.1037/0022-006X.46.1.139 10.1523/JNEUROSCI.21-16-j0002.2001 10.1038/nn1584 10.1016/S0741-8329(96)00084-5 10.1001/archpsyc.60.9.929 10.1037/0021-843X.117.1.63 10.1037/0021-843X.111.1.124 10.1016/j.drugalcdep.2006.12.011 10.1146/annurev.psych.59.103006.093548 10.1017/S0954579499002369 10.1017/S0033291708003085 10.1016/j.drugalcdep.2006.12.014 10.1016/j.bbr.2006.10.034 10.1207/S15374424JCCP3003_4 10.15288/jsa.1994.55.149 10.1080/02791072.2000.10736099 10.1016/S0272-7358(05)80002-9 10.1016/j.neuroimage.2006.11.043 10.1523/JNEUROSCI.4862-03.2004 10.1016/j.neuroimage.2006.05.027 10.1111/1469-7610.00364 10.1007/PL00005481 10.1016/j.biopsych.2003.11.008 |
| ContentType | Journal Article |
| Copyright | 2008 Society for the Study of Addiction. No claim to original US government works 2008 INIST-CNRS Journal compilation © 2008 Society for the Study of Addiction |
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| Issue | 8 |
| Keywords | Adolescence sensation- seeking Central nervous system Activation Encephalon Sensation seeking Alcoholic beverage incentives striatum at-risk children Child Human Incentive alcohol Drug addiction Impulsivity Ethanol Alcoholism Basal ganglion Corpus striatum Nucleus accumbens Addiction ventral Adolescent Risk factor Reward Psychiatry |
| Language | English |
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| PublicationDate | August 2008 |
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| PublicationTitle | Addiction (Abingdon, England) |
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| PublicationYear | 2008 |
| Publisher | Blackwell Publishing Ltd Blackwell |
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| References | Gottfried J. A., O'Doherty J., Dolan R. J. Appetitive and aversive olfactory learning in humans studied using event-related functional magnetic resonance imaging. J Neurosci 2002; 22: 10829-37. Clark D. B., Lesnick L., Hegedus A. M. Traumas and other adverse life events in adolescents with alcohol abuse and dependence. J Am Acad Child Adolesc Psychiatry 1997; 36: 1744-51. Delgado M. R., Nystrom L. E., Fissell C., Noll D. C., Fiez J. A. Tracking the hemodynamic responses to reward and punishment in the striatum. J Neurophysiol 2000; 84: 3072-7. Blum K., Braverman E. R., Holder J. M., Lubar J. F., Monastra V. J., Miller D. et al. Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors. J Psychoactive Drugs 2000; 32: 1-112. Bucholz K. K., Cadoret R., Cloninger C. R., Dinwiddie S. H., Hesselbrock V. M., Nurnberger J. I. et al. A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA. J Stud Alcohol 1994; 55: 149-58. Barnow S., Schuckit M., Smith T. L., Preuss U., Danko G. The relationship between the family density of alcoholism and externalizing symptoms among 146 children. Alcohol Alcohol 2002; 37: 383-7. Wu P., Bird H. R., Liu X., Fan B., Fuller C., Shen S. et al. Childhood depressive symptoms and early onset of alcohol use. Pediatrics 2006; 118: 1907-15. Cox R. W. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res 1996; 29: 162-73. Hussong A., Bauer D., Chassin L. Telescoped trajectories from alcohol initiation to disorder in children of alcoholic parents. J Abnorm Psychol 2008; 117: 63-78. Ratsma J. E., Van Der Stelt O., Gunning W. B. Neurochemical markers of alcoholism vulnerability in humans. Alcohol Alcohol 2002; 37: 522-33. Bechara A. Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. Nat Neurosci 2005; 8: 1458-63. Gordis E. Contributions of behavioral science to alcohol research: understanding who is at risk and why. Exp Clin Psychopharmacol 2000; 8: 264-70. Knutson B., Taylor J., Kaufman M., Peterson R., Glover G. Distributed neural representation of expected value. J Neurosci 2005; 25: 4806-12. Knutson B., Cooper J. C. Functional magnetic resonance imaging of reward prediction. Curr Opin Neurol 2005; 18: 411-17. Scheres A., Milham M. P., Knutson B., Castellanos F. X. Ventral striatal hyporesponsiveness during reward anticipation in attention-deficit/hyperactivity disorder. Biol Psychiatry 2007; 61: 720-4. Koob G. F., Moal L. M. Addiction and the brain antireward system. Annu Rev Psychol 2008; 59: 29-53. Matthys W., Van Goozen S. H., De Vries H., Cohen-Kettenis P. T., Van Engeland H. The dominance of behavioural activation over behavioural inhibition in conduct disordered boys with or without attention deficit hyperactivity disorder. J Child Psychol Psychiatry 1998; 39: 643-51. Young S. E., Stallings M. C., Corley R. P., Krauter K. S., Hewitt J. K. Genetic and environmental influences on behavioral disinhibition. Am J Med Genet 2000; 96: 684-95. Zuckerman M., Eysenck S., Eysenck H. J. Sensation seeking in England and America: cross-cultural, age, and sex comparisons. J Consult Clin Psychol 1978; 46: 139-49. Slutske W. S., Heath A. C., Dinwiddie S. H., Madden P. A., Bucholz K. K., Dunne M. P. et al. Common genetic risk factors for conduct disorder and alcohol dependence. J Abnorm Psychol 1998; 107: 363-74. Reich W. Diagnostic interview for children and adolescents (DICA). J Am Acad Child Adolesc Psychiatry 2000; 39: 59-66. Wrase J., Schlagenhauf F., Kienast T., Wustenberg T., Bermpohl F., Kahnt T. et al. Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics. Neuroimage 2007; 35: 787-94. Bjork J. M., Hommer D. W. Anticipating instrumentally obtained and passively-received rewards: a factorial fMRI investigation. Behav Brain Res 2007; 177: 165-70. Galvan A., Hare T. A., Davidson M., Spicer J., Glover G., Casey B. J. The role of ventral frontostriatal circuitry in reward-based learning in humans. J Neurosci 2005; 25: 8650-6. Evenden J. L. Varieties of impulsivity. Psychopharmacology (Berl) 1999; 146: 348-61. Knutson B., Adams C. M., Fong G. W., Hommer D. Anticipation of increasing monetary reward selectively recruits nucleus accumbens. J Neurosci 2001; 21: RC159. Pardini D., White H. R., Stouthamer-Loeber M. Early adolescent psychopathology as a predictor of alcohol use disorders by young adulthood. Drug Alcohol Depend 2007; 88: S38-49. Bjork J. M., Knutson B., Fong G. W., Caggiano D. M., Bennett S. M., Hommer D. W. Incentive-elicited brain activation in adolescents: similarities and differences from young adults. J Neurosci 2004; 24: 1793-802. Kendler K. S., Davis C. G., Kessler R. C. The familial aggregation of common psychiatric and substance use disorders in the National Comorbidity Survey: a family history study. Br J Psychiatry 1997; 170: 541-8. May J. C., Delgado M. R., Dahl R. E., Stenger V. A., Ryan N. D., Fiez J. A. et al. Event-related functional magnetic resonance imaging of reward-related brain circuitry in children and adolescents. Biol Psychiatry 2004; 55: 359-66. Fergusson D. M., Horwood L. J., Ridder E. M. Conduct and attentional problems in childhood and adolescence and later substance use, abuse and dependence: results of a 25-year longitudinal study. Drug Alcohol Depend 2007; 88: S14-26. Prensa L., Richard S., Parent A. Chemical anatomy of the human ventral striatum and adjacent basal forebrain structures. J Comp Neurol 2003; 460: 345-67. Ozkaragoz T., Satz P., Noble E. P. Neuropsychological functioning in sons of active alcoholic, recovering alcoholic, and social drinking fathers. Alcohol 1997; 14: 31-7. Kendler K. S., Prescott C. A., Myers J., Neale M. C. The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry 2003; 60: 929-37. Achenbach T. M. Manual For The Child Behavior Checklist/4-18 And 1991 Profile. Burlington, VT: University of Vermont, Department of Psychiatry; 1991. Giancola P. R., Moss H. B. Executive cognitive functioning in alcohol use disorders. Recent Dev Alcohol 1998; 14: 227-51. Kaplow J. B., Curran P. J., Angold A., Costello E. J. The prospective relation between dimensions of anxiety and the initiation of adolescent alcohol use. J Clin Child Psychol 2001; 30: 316-26. Hoyle R. H., Stephenson M. T., Palmgreen P., Lorch E. P., Donohew R. L. Reliability and validity of a brief measure of sensation seeking. Pers Individ Dif 2002; 32: 401-14. Carlsson K., Andersson J., Petrovic P., Petersson K. M., Ohman A., Ingvar M. Predictability modulates the affective and sensory-discriminative neural processing of pain. Neuroimage 2006; 32: 1804-14. Schulteis G., Markou A., Cole M., Koob G. F. Decreased brain reward produced by ethanol withdrawal. Proc Natl Acad Sci USA 1995; 92: 5880-4. Clark D. B., Kirisci L., Moss H. B. Early adolescent gateway drug use in sons of fathers with substance use disorders. Addict Behav 1998; 23: 561-6. Galvan A., Hare T. A., Parra C. E., Penn J., Voss H., Glover G. et al. Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents. J Neurosci 2006; 26: 6885-92. Enoch M. A. Genetic and environmental influences on the development of alcoholism: resilience vs. risk. Ann NY Acad Sci 2006; 1094: 193-201. Johnson J. L., Leff M. Children of substance abusers: overview of research findings. Pediatrics 1999; 103: 1085-99. Heitzeg M. M., Nigg J. T., Yau W. Y., Zubieta J. K., Zucker R. A. Affective circuitry and risk for alcoholism in late adolescence: differences in frontostriatal responses between vulnerable and resilient children of alcoholic parents. Alcohol Clin Exp Res 2008; 32: 414-26. Newman J. P., Wallace J. F. Diverse pathways to deficient self-regulation: implications for disinhibitory psychopathology in children. Clin Psychol Rev 1993; 13: 699-720. Schuckit M. A. Biological, psychological and environmental predictors of the alcoholism risk: a longitudinal study. J Stud Alcohol 1998; 59: 485-94. Slutske W. S., Heath A. C., Madden P. A., Bucholz K. K., Statham D. J., Martin N. G. Personality and the genetic risk for alcohol dependence. J Abnorm Psychol 2002; 111: 124-33. Buss A. H., Plomin R. A Temperament Theory of Personality Development. New York: Wiley; 1975. Iacono W. G., Carlson S. R., Taylor J., Elkins I. J., McGue M. Behavioral disinhibition and the development of substance-use disorders: findings from the Minnesota Twin Family Study. Dev Psychopathol 1999; 11: 869-900. 2002; 37 1995; 92 2006; 32 2000; 8 2002; 32 2002; 111 2004; 24 2008 2008; 59 1975 2008; 32 1999; 146 1999; 103 1991 2006; 118 2007; 35 1998; 23 2001; 21 2005; 25 1998; 59 2004; 55 1993; 13 1998; 39 1996; 29 2000; 39 2000; 32 1997; 36 2007; 177 1997; 14 2005; 8 2000; 96 2002; 22 2006; 26 1998; 107 1994; 55 2000; 84 1999; 11 2008; 117 2007; 61 1997; 170 1978; 46 2003; 60 2007; 88 2005; 18 2001; 30 2006; 1094 1998; 14 2003; 460 e_1_2_6_51_2 e_1_2_6_30_2 e_1_2_6_19_2 e_1_2_6_13_2 e_1_2_6_34_2 e_1_2_6_11_2 e_1_2_6_32_2 e_1_2_6_17_2 e_1_2_6_38_2 Buss A. H. (e_1_2_6_40_2) 1975 e_1_2_6_15_2 e_1_2_6_36_2 e_1_2_6_20_2 e_1_2_6_41_2 e_1_2_6_7_2 e_1_2_6_9_2 e_1_2_6_3_2 e_1_2_6_5_2 e_1_2_6_24_2 e_1_2_6_47_2 e_1_2_6_49_2 e_1_2_6_28_2 e_1_2_6_43_2 e_1_2_6_26_2 e_1_2_6_45_2 e_1_2_6_50_2 e_1_2_6_52_2 e_1_2_6_31_2 e_1_2_6_18_2 Achenbach T. M. (e_1_2_6_22_2) 1991 e_1_2_6_12_2 e_1_2_6_35_2 e_1_2_6_10_2 e_1_2_6_33_2 e_1_2_6_16_2 e_1_2_6_39_2 e_1_2_6_14_2 e_1_2_6_37_2 e_1_2_6_42_2 e_1_2_6_8_2 e_1_2_6_29_2 e_1_2_6_4_2 e_1_2_6_6_2 e_1_2_6_23_2 e_1_2_6_48_2 e_1_2_6_2_2 e_1_2_6_21_2 e_1_2_6_27_2 e_1_2_6_44_2 e_1_2_6_25_2 e_1_2_6_46_2 |
| References_xml | – reference: Bjork J. M., Hommer D. W. Anticipating instrumentally obtained and passively-received rewards: a factorial fMRI investigation. Behav Brain Res 2007; 177: 165-70. – reference: Heitzeg M. M., Nigg J. T., Yau W. Y., Zubieta J. K., Zucker R. A. Affective circuitry and risk for alcoholism in late adolescence: differences in frontostriatal responses between vulnerable and resilient children of alcoholic parents. Alcohol Clin Exp Res 2008; 32: 414-26. – reference: Galvan A., Hare T. A., Davidson M., Spicer J., Glover G., Casey B. J. The role of ventral frontostriatal circuitry in reward-based learning in humans. J Neurosci 2005; 25: 8650-6. – reference: Wu P., Bird H. R., Liu X., Fan B., Fuller C., Shen S. et al. Childhood depressive symptoms and early onset of alcohol use. Pediatrics 2006; 118: 1907-15. – reference: Hussong A., Bauer D., Chassin L. Telescoped trajectories from alcohol initiation to disorder in children of alcoholic parents. J Abnorm Psychol 2008; 117: 63-78. – reference: Giancola P. R., Moss H. B. Executive cognitive functioning in alcohol use disorders. Recent Dev Alcohol 1998; 14: 227-51. – reference: Reich W. Diagnostic interview for children and adolescents (DICA). J Am Acad Child Adolesc Psychiatry 2000; 39: 59-66. – reference: Blum K., Braverman E. R., Holder J. M., Lubar J. F., Monastra V. J., Miller D. et al. Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors. J Psychoactive Drugs 2000; 32: 1-112. – reference: Gottfried J. A., O'Doherty J., Dolan R. J. Appetitive and aversive olfactory learning in humans studied using event-related functional magnetic resonance imaging. J Neurosci 2002; 22: 10829-37. – reference: Bechara A. Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. Nat Neurosci 2005; 8: 1458-63. – reference: Kendler K. S., Davis C. G., Kessler R. C. The familial aggregation of common psychiatric and substance use disorders in the National Comorbidity Survey: a family history study. Br J Psychiatry 1997; 170: 541-8. – reference: Kaplow J. B., Curran P. J., Angold A., Costello E. J. The prospective relation between dimensions of anxiety and the initiation of adolescent alcohol use. J Clin Child Psychol 2001; 30: 316-26. – reference: Delgado M. R., Nystrom L. E., Fissell C., Noll D. C., Fiez J. A. Tracking the hemodynamic responses to reward and punishment in the striatum. J Neurophysiol 2000; 84: 3072-7. – reference: Slutske W. S., Heath A. C., Dinwiddie S. H., Madden P. A., Bucholz K. K., Dunne M. P. et al. Common genetic risk factors for conduct disorder and alcohol dependence. J Abnorm Psychol 1998; 107: 363-74. – reference: Clark D. B., Kirisci L., Moss H. B. Early adolescent gateway drug use in sons of fathers with substance use disorders. Addict Behav 1998; 23: 561-6. – reference: Fergusson D. M., Horwood L. J., Ridder E. M. Conduct and attentional problems in childhood and adolescence and later substance use, abuse and dependence: results of a 25-year longitudinal study. Drug Alcohol Depend 2007; 88: S14-26. – reference: Slutske W. S., Heath A. C., Madden P. A., Bucholz K. K., Statham D. J., Martin N. G. Personality and the genetic risk for alcohol dependence. J Abnorm Psychol 2002; 111: 124-33. – reference: Scheres A., Milham M. P., Knutson B., Castellanos F. X. Ventral striatal hyporesponsiveness during reward anticipation in attention-deficit/hyperactivity disorder. Biol Psychiatry 2007; 61: 720-4. – reference: Enoch M. A. Genetic and environmental influences on the development of alcoholism: resilience vs. risk. Ann NY Acad Sci 2006; 1094: 193-201. – reference: Wrase J., Schlagenhauf F., Kienast T., Wustenberg T., Bermpohl F., Kahnt T. et al. Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics. Neuroimage 2007; 35: 787-94. – reference: Knutson B., Adams C. M., Fong G. W., Hommer D. Anticipation of increasing monetary reward selectively recruits nucleus accumbens. J Neurosci 2001; 21: RC159. – reference: Pardini D., White H. R., Stouthamer-Loeber M. Early adolescent psychopathology as a predictor of alcohol use disorders by young adulthood. Drug Alcohol Depend 2007; 88: S38-49. – reference: Johnson J. L., Leff M. Children of substance abusers: overview of research findings. Pediatrics 1999; 103: 1085-99. – reference: Schuckit M. A. Biological, psychological and environmental predictors of the alcoholism risk: a longitudinal study. J Stud Alcohol 1998; 59: 485-94. – reference: Bjork J. M., Knutson B., Fong G. W., Caggiano D. M., Bennett S. M., Hommer D. W. Incentive-elicited brain activation in adolescents: similarities and differences from young adults. J Neurosci 2004; 24: 1793-802. – reference: Achenbach T. M. Manual For The Child Behavior Checklist/4-18 And 1991 Profile. Burlington, VT: University of Vermont, Department of Psychiatry; 1991. – reference: Koob G. F., Moal L. M. Addiction and the brain antireward system. Annu Rev Psychol 2008; 59: 29-53. – reference: Buss A. H., Plomin R. A Temperament Theory of Personality Development. New York: Wiley; 1975. – reference: Clark D. B., Lesnick L., Hegedus A. M. Traumas and other adverse life events in adolescents with alcohol abuse and dependence. J Am Acad Child Adolesc Psychiatry 1997; 36: 1744-51. – reference: Knutson B., Taylor J., Kaufman M., Peterson R., Glover G. Distributed neural representation of expected value. J Neurosci 2005; 25: 4806-12. – reference: Barnow S., Schuckit M., Smith T. L., Preuss U., Danko G. The relationship between the family density of alcoholism and externalizing symptoms among 146 children. Alcohol Alcohol 2002; 37: 383-7. – reference: Ratsma J. E., Van Der Stelt O., Gunning W. B. Neurochemical markers of alcoholism vulnerability in humans. Alcohol Alcohol 2002; 37: 522-33. – reference: Cox R. W. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res 1996; 29: 162-73. – reference: May J. C., Delgado M. R., Dahl R. E., Stenger V. A., Ryan N. D., Fiez J. A. et al. Event-related functional magnetic resonance imaging of reward-related brain circuitry in children and adolescents. Biol Psychiatry 2004; 55: 359-66. – reference: Zuckerman M., Eysenck S., Eysenck H. J. Sensation seeking in England and America: cross-cultural, age, and sex comparisons. J Consult Clin Psychol 1978; 46: 139-49. – reference: Ozkaragoz T., Satz P., Noble E. P. Neuropsychological functioning in sons of active alcoholic, recovering alcoholic, and social drinking fathers. Alcohol 1997; 14: 31-7. – reference: Kendler K. S., Prescott C. A., Myers J., Neale M. C. The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry 2003; 60: 929-37. – reference: Bucholz K. K., Cadoret R., Cloninger C. R., Dinwiddie S. H., Hesselbrock V. M., Nurnberger J. I. et al. A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA. J Stud Alcohol 1994; 55: 149-58. – reference: Hoyle R. H., Stephenson M. T., Palmgreen P., Lorch E. P., Donohew R. L. Reliability and validity of a brief measure of sensation seeking. Pers Individ Dif 2002; 32: 401-14. – reference: Knutson B., Cooper J. C. Functional magnetic resonance imaging of reward prediction. Curr Opin Neurol 2005; 18: 411-17. – reference: Carlsson K., Andersson J., Petrovic P., Petersson K. M., Ohman A., Ingvar M. Predictability modulates the affective and sensory-discriminative neural processing of pain. Neuroimage 2006; 32: 1804-14. – reference: Evenden J. L. Varieties of impulsivity. Psychopharmacology (Berl) 1999; 146: 348-61. – reference: Matthys W., Van Goozen S. H., De Vries H., Cohen-Kettenis P. T., Van Engeland H. The dominance of behavioural activation over behavioural inhibition in conduct disordered boys with or without attention deficit hyperactivity disorder. J Child Psychol Psychiatry 1998; 39: 643-51. – reference: Iacono W. G., Carlson S. R., Taylor J., Elkins I. J., McGue M. Behavioral disinhibition and the development of substance-use disorders: findings from the Minnesota Twin Family Study. Dev Psychopathol 1999; 11: 869-900. – reference: Schulteis G., Markou A., Cole M., Koob G. F. Decreased brain reward produced by ethanol withdrawal. Proc Natl Acad Sci USA 1995; 92: 5880-4. – reference: Prensa L., Richard S., Parent A. Chemical anatomy of the human ventral striatum and adjacent basal forebrain structures. J Comp Neurol 2003; 460: 345-67. – reference: Galvan A., Hare T. A., Parra C. E., Penn J., Voss H., Glover G. et al. Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents. J Neurosci 2006; 26: 6885-92. – reference: Gordis E. Contributions of behavioral science to alcohol research: understanding who is at risk and why. Exp Clin Psychopharmacol 2000; 8: 264-70. – reference: Young S. E., Stallings M. C., Corley R. P., Krauter K. S., Hewitt J. K. Genetic and environmental influences on behavioral disinhibition. Am J Med Genet 2000; 96: 684-95. – reference: Newman J. P., Wallace J. F. Diverse pathways to deficient self-regulation: implications for disinhibitory psychopathology in children. Clin Psychol Rev 1993; 13: 699-720. – volume: 22 start-page: 10829 year: 2002 end-page: 37 article-title: Appetitive and aversive olfactory learning in humans studied using event‐related functional magnetic resonance imaging publication-title: J Neurosci – volume: 88 start-page: S14 year: 2007 article-title: Conduct and attentional problems in childhood and adolescence and later substance use, abuse and dependence: results of a 25‐year longitudinal study publication-title: Drug Alcohol Depend – volume: 11 start-page: 869 year: 1999 end-page: 900 article-title: Behavioral disinhibition and the development of substance‐use disorders: findings from the Minnesota Twin Family Study publication-title: Dev Psychopathol – volume: 1094 start-page: 193 year: 2006 end-page: 201 article-title: Genetic and environmental influences on the development of alcoholism: resilience vs. risk publication-title: Ann NY Acad Sci – volume: 177 start-page: 165 year: 2007 end-page: 70 article-title: Anticipating instrumentally obtained and passively‐received rewards: a factorial fMRI investigation publication-title: Behav Brain Res – volume: 460 start-page: 345 year: 2003 end-page: 67 article-title: Chemical anatomy of the human ventral striatum and adjacent basal forebrain structures publication-title: J Comp Neurol – year: 1975 – volume: 8 start-page: 264 year: 2000 end-page: 70 article-title: Contributions of behavioral science to alcohol research: understanding who is at risk and why publication-title: Exp Clin Psychopharmacol – volume: 61 start-page: 720 year: 2007 end-page: 4 article-title: Ventral striatal hyporesponsiveness during reward anticipation in attention‐deficit/hyperactivity disorder publication-title: Biol Psychiatry – volume: 21 start-page: RC159 year: 2001 article-title: Anticipation of increasing monetary reward selectively recruits nucleus accumbens publication-title: J Neurosci – volume: 55 start-page: 149 year: 1994 end-page: 58 article-title: A new, semi‐structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA publication-title: J Stud Alcohol – volume: 25 start-page: 8650 year: 2005 end-page: 6 article-title: The role of ventral frontostriatal circuitry in reward‐based learning in humans publication-title: J Neurosci – volume: 92 start-page: 5880 year: 1995 end-page: 4 article-title: Decreased brain reward produced by ethanol withdrawal publication-title: Proc Natl Acad Sci USA – volume: 26 start-page: 6885 year: 2006 end-page: 92 article-title: Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk‐taking behavior in adolescents publication-title: J Neurosci – volume: 59 start-page: 485 year: 1998 end-page: 94 article-title: Biological, psychological and environmental predictors of the alcoholism risk: a longitudinal study publication-title: J Stud Alcohol – volume: 32 start-page: 414 year: 2008 end-page: 26 article-title: Affective circuitry and risk for alcoholism in late adolescence: differences in frontostriatal responses between vulnerable and resilient children of alcoholic parents publication-title: Alcohol Clin Exp Res – volume: 96 start-page: 684 year: 2000 end-page: 95 article-title: Genetic and environmental influences on behavioral disinhibition publication-title: Am J Med Genet – volume: 36 start-page: 1744 year: 1997 end-page: 51 article-title: Traumas and other adverse life events in adolescents with alcohol abuse and dependence publication-title: J Am Acad Child Adolesc Psychiatry – volume: 146 start-page: 348 year: 1999 end-page: 61 article-title: Varieties of impulsivity publication-title: Psychopharmacology (Berl) – year: 2008 – volume: 24 start-page: 1793 year: 2004 end-page: 802 article-title: Incentive‐elicited brain activation in adolescents: similarities and differences from young adults publication-title: J Neurosci – volume: 29 start-page: 162 year: 1996 end-page: 73 article-title: AFNI: software for analysis and visualization of functional magnetic resonance neuroimages publication-title: Comput Biomed Res – volume: 32 start-page: 1 year: 2000 end-page: 112 article-title: Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors publication-title: J Psychoactive Drugs – volume: 32 start-page: 401 year: 2002 end-page: 14 article-title: Reliability and validity of a brief measure of sensation seeking publication-title: Pers Individ Dif – volume: 55 start-page: 359 year: 2004 end-page: 66 article-title: Event‐related functional magnetic resonance imaging of reward‐related brain circuitry in children and adolescents publication-title: Biol Psychiatry – volume: 170 start-page: 541 year: 1997 end-page: 8 article-title: The familial aggregation of common psychiatric and substance use disorders in the National Comorbidity Survey: a family history study publication-title: Br J Psychiatry – volume: 14 start-page: 31 year: 1997 end-page: 7 article-title: Neuropsychological functioning in sons of active alcoholic, recovering alcoholic, and social drinking fathers publication-title: Alcohol – volume: 13 start-page: 699 year: 1993 end-page: 720 article-title: Diverse pathways to deficient self‐regulation: implications for disinhibitory psychopathology in children publication-title: Clin Psychol Rev – volume: 30 start-page: 316 year: 2001 end-page: 26 article-title: The prospective relation between dimensions of anxiety and the initiation of adolescent alcohol use publication-title: J Clin Child Psychol – volume: 88 start-page: S38 year: 2007 article-title: Early adolescent psychopathology as a predictor of alcohol use disorders by young adulthood publication-title: Drug Alcohol Depend – volume: 35 start-page: 787 year: 2007 end-page: 94 article-title: Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics publication-title: Neuroimage – volume: 37 start-page: 522 year: 2002 end-page: 33 article-title: Neurochemical markers of alcoholism vulnerability in humans publication-title: Alcohol Alcohol – volume: 14 start-page: 227 year: 1998 end-page: 51 article-title: Executive cognitive functioning in alcohol use disorders publication-title: Recent Dev Alcohol – volume: 23 start-page: 561 year: 1998 end-page: 6 article-title: Early adolescent gateway drug use in sons of fathers with substance use disorders publication-title: Addict Behav – volume: 84 start-page: 3072 year: 2000 end-page: 7 article-title: Tracking the hemodynamic responses to reward and punishment in the striatum publication-title: J Neurophysiol – volume: 59 start-page: 29 year: 2008 end-page: 53 article-title: Addiction and the brain antireward system publication-title: Annu Rev Psychol – volume: 37 start-page: 383 year: 2002 end-page: 7 article-title: The relationship between the family density of alcoholism and externalizing symptoms among 146 children publication-title: Alcohol Alcohol – volume: 8 start-page: 1458 year: 2005 end-page: 63 article-title: Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective publication-title: Nat Neurosci – volume: 117 start-page: 63 year: 2008 end-page: 78 article-title: Telescoped trajectories from alcohol initiation to disorder in children of alcoholic parents publication-title: J Abnorm Psychol – volume: 107 start-page: 363 year: 1998 end-page: 74 article-title: Common genetic risk factors for conduct disorder and alcohol dependence publication-title: J Abnorm Psychol – volume: 32 start-page: 1804 year: 2006 end-page: 14 article-title: Predictability modulates the affective and sensory‐discriminative neural processing of pain publication-title: Neuroimage – volume: 103 start-page: 1085 year: 1999 end-page: 99 article-title: Children of substance abusers: overview of research findings publication-title: Pediatrics – volume: 60 start-page: 929 year: 2003 end-page: 37 article-title: The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women publication-title: Arch Gen Psychiatry – volume: 39 start-page: 59 year: 2000 end-page: 66 article-title: Diagnostic interview for children and adolescents (DICA) publication-title: J Am Acad Child Adolesc Psychiatry – volume: 111 start-page: 124 year: 2002 end-page: 33 article-title: Personality and the genetic risk for alcohol dependence publication-title: J Abnorm Psychol – volume: 46 start-page: 139 year: 1978 end-page: 49 article-title: Sensation seeking in England and America: cross‐cultural, age, and sex comparisons publication-title: J Consult Clin Psychol – volume: 39 start-page: 643 year: 1998 end-page: 51 article-title: The dominance of behavioural activation over behavioural inhibition in conduct disordered boys with or without attention deficit hyperactivity disorder publication-title: J Child Psychol Psychiatry – volume: 118 start-page: 1907 year: 2006 end-page: 15 article-title: Childhood depressive symptoms and early onset of alcohol use publication-title: Pediatrics – year: 1991 – volume: 18 start-page: 411 year: 2005 end-page: 17 article-title: Functional magnetic resonance imaging of reward prediction publication-title: Curr Opin Neurol – volume: 25 start-page: 4806 year: 2005 end-page: 12 article-title: Distributed neural representation of expected value publication-title: J Neurosci – ident: e_1_2_6_31_2 doi: 10.1152/jn.2000.84.6.3072 – ident: e_1_2_6_11_2 doi: 10.1037/0021-843X.107.3.363 – ident: e_1_2_6_10_2 doi: 10.1192/bjp.170.6.541 – ident: e_1_2_6_5_2 doi: 10.1097/00004583-199712000-00023 – volume-title: Manual For The Child Behavior Checklist/4‐18 And 1991 Profile year: 1991 ident: e_1_2_6_22_2 – ident: e_1_2_6_50_2 doi: 10.1523/JNEUROSCI.2431-05.2005 – ident: e_1_2_6_4_2 doi: 10.1093/alcalc/37.6.522 – ident: e_1_2_6_25_2 doi: 10.1006/cbmr.1996.0014 – ident: e_1_2_6_27_2 doi: 10.1016/j.biopsych.2006.04.042 – ident: e_1_2_6_42_2 doi: 10.1523/JNEUROSCI.1062-06.2006 – ident: e_1_2_6_23_2 doi: 10.1016/S0191-8869(01)00032-0 – ident: e_1_2_6_28_2 doi: 10.1002/cne.10627 – ident: e_1_2_6_51_2 doi: 10.1097/01.wco.0000173463.24758.f6 – ident: e_1_2_6_39_2 doi: 10.1093/alcalc/37.4.383 – volume-title: A Temperament Theory of Personality Development year: 1975 ident: e_1_2_6_40_2 – ident: e_1_2_6_12_2 doi: 10.1002/1096-8628(20001009)96:5<684::AID-AJMG16>3.0.CO;2-G – ident: e_1_2_6_6_2 doi: 10.1196/annals.1376.019 – ident: e_1_2_6_7_2 doi: 10.1542/peds.2006-1221 – ident: e_1_2_6_36_2 doi: 10.1111/j.1530-0277.2007.00605.x – ident: e_1_2_6_9_2 doi: 10.1542/peds.103.S2.1085 – ident: e_1_2_6_30_2 doi: 10.1523/JNEUROSCI.22-24-10829.2002 – ident: e_1_2_6_48_2 doi: 10.1016/S0306-4603(98)00038-0 – ident: e_1_2_6_26_2 doi: 10.1523/JNEUROSCI.0642-05.2005 – ident: e_1_2_6_20_2 doi: 10.1097/00004583-200001000-00017 – ident: e_1_2_6_3_2 doi: 10.15288/jsa.1998.59.485 – ident: e_1_2_6_34_2 doi: 10.1073/pnas.92.13.5880 – ident: e_1_2_6_49_2 doi: 10.1007/0-306-47148-5_10 – ident: e_1_2_6_2_2 doi: 10.1037/1064-1297.8.3.264 – ident: e_1_2_6_24_2 doi: 10.1037/0022-006X.46.1.139 – ident: e_1_2_6_19_2 doi: 10.1523/JNEUROSCI.21-16-j0002.2001 – ident: e_1_2_6_45_2 doi: 10.1038/nn1584 – ident: e_1_2_6_37_2 doi: 10.1016/S0741-8329(96)00084-5 – ident: e_1_2_6_15_2 doi: 10.1001/archpsyc.60.9.929 – ident: e_1_2_6_38_2 doi: 10.1037/0021-843X.117.1.63 – ident: e_1_2_6_46_2 doi: 10.1037/0021-843X.111.1.124 – ident: e_1_2_6_35_2 doi: 10.1016/j.drugalcdep.2006.12.011 – ident: e_1_2_6_33_2 doi: 10.1146/annurev.psych.59.103006.093548 – ident: e_1_2_6_47_2 doi: 10.1017/S0954579499002369 – ident: e_1_2_6_13_2 doi: 10.1017/S0033291708003085 – ident: e_1_2_6_14_2 doi: 10.1016/j.drugalcdep.2006.12.014 – ident: e_1_2_6_32_2 doi: 10.1016/j.bbr.2006.10.034 – ident: e_1_2_6_8_2 doi: 10.1207/S15374424JCCP3003_4 – ident: e_1_2_6_21_2 doi: 10.15288/jsa.1994.55.149 – ident: e_1_2_6_16_2 doi: 10.1080/02791072.2000.10736099 – ident: e_1_2_6_44_2 doi: 10.1016/S0272-7358(05)80002-9 – ident: e_1_2_6_17_2 doi: 10.1016/j.neuroimage.2006.11.043 – ident: e_1_2_6_18_2 doi: 10.1523/JNEUROSCI.4862-03.2004 – ident: e_1_2_6_29_2 doi: 10.1016/j.neuroimage.2006.05.027 – ident: e_1_2_6_43_2 doi: 10.1111/1469-7610.00364 – ident: e_1_2_6_41_2 doi: 10.1007/PL00005481 – ident: e_1_2_6_52_2 doi: 10.1016/j.biopsych.2003.11.008 |
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Aims Deficient recruitment of motivational circuitry by non‐drug rewards has been postulated as a pre‐morbid risk factor for substance dependence... Aims Deficient recruitment of motivational circuitry by non‐drug rewards has been postulated as a pre‐morbid risk factor for substance dependence (SD). We... Deficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We tested... Aims: Deficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We... Aims Deficient recruitment of motivational circuitry by non-drug rewards has been postulated as a pre-morbid risk factor for substance dependence (SD). We... |
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| SubjectTerms | Addiction Addictive behaviors Adolescence Adolescent Adolescents Adult and adolescent clinical studies alcohol Alcoholics Alcoholism Alcoholism - psychology Alcoholism and acute alcohol poisoning Analysis of Variance at-risk children Behavior, Addictive - psychology Biological and medical sciences Brain Mapping Caudate Nucleus - physiology Cerebral Cortex - physiopathology Child Child of Impaired Parents - psychology Children Children of alcoholics Clinical psychology Cues Experimental psychology Female General aspects Humans impulsivity Incentives Longitudinal Studies Magnetic Resonance Imaging Male Medical sciences Motivation Neural Pathways - physiopathology Neurology NMR Nuclear magnetic resonance nucleus accumbens Nucleus Accumbens - physiology Parents Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry reward Risk factors Risk-Taking sensation-seeking Social problems striatum Teenagers Toxicology U.S.A ventral |
| Title | Incentive-elicited striatal activation in adolescent children of alcoholics |
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