Serum miR-29a Is Upregulated in Acute Graft-versus-Host Disease and Activates Dendritic Cells through TLR Binding - Ranganathan, Parvathi; Ngankeu, Apollinaire; Zitzer, Nina C; Leoncini, PierPaolo; Yu, Xueyan; Casadei, Lucia; Challagundla, Kishore; Reichenbach, Dawn K; Garman, Sabrina; Ruppert, Amy S; Volinia, Stefano; Hofstetter, Jessica; et al. (The Journal of immunology (1950), 2017)
Keywords: Acute Disease; Cell activation; Cohort Studies; Dendritic cells; Dendritic Cells - physiology; Graft vs Host Disease - diagnosis; Graft vs Host Disease - genetics; Graft vs Leukemia Effect - genetics; Graft-versus-host reaction; Hematopoietic Stem Cell Transplantation; Hematopoietic stem cells; Humans; Inflammation; Inflammation - genetics; Interleukin 6; Interleukin-6 - metabolism; MicroRNAs - biosynthesis; MicroRNAs - blood; Middle Aged; miRNA; NF-kappa B - metabolism; NF-κB protein; Nucleic acids; Prognosis; RNA, Small Interfering - genetics; Rodents; Signal Transduction; Stem cell transplantation; TLR7 protein; Toll-Like Receptor 7 - metabolism; Toll-Like Receptor 8 - metabolism; Toll-like receptors; Transplantation; Transplantation, Homologous; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-α; Up-Regulation