Depression and incident Alzheimer disease: the impact of disease severity

• Published in: The American journal of geriatric psychiatry Vol. 23; no. 2; p. 119
• Main Authors: Gracia-García, Patricia, de-la-Cámara, Concepción, Santabárbara, Javier, Lopez-Anton, Raúl, Quintanilla, Miguel Angel, Ventura, Tirso, Marcos, Guillermo, Campayo, Antonio, Saz, Pedro, Lyketsos, Constantine, Lobo, Antonio
• Format: Journal Article
• Language: English
• Published: England 01.02.2015
• Subjects: Aged; Alzheimer Disease - epidemiology; Comorbidity; Depression - epidemiology; Female; Humans; Incidence; Longitudinal Studies; Male; Psychiatric Status Rating Scales; Risk Factors; Spain - epidemiology; Spain; depression; Alzheimer's disease; incidence; Risk factor

To test the hypothesis that clinically significant depression (particularly severe depression) increases the risk of Alzheimer's disease (AD). A longitudinal, three-wave epidemiologic study was implemented in a sample of individuals aged 55 years and older (n = 4,803) followed up at 2.5 years a...