Rapid Evaluation of Antibacterial Carbohydrates on a Microfluidic Chip Integrated with the Impedimetric Neoglycoprotein Biosensor

• Published in: Biosensors (Basel) Vol. 13; no. 9; p. 887
• Main Authors: Ji, Haijie, Yang, Xueqiong, Zhou, Hang, Cui, Feiyun, Zhou, Qin
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.09.2023; MDPI
• Subjects: Adhesion; Adhesives; antiadhesive carbohydrates; Antibacterial activity; Antibacterial agents; Antibiotics; Antiinfectives and antibacterials; Bacteria; Bacterial infections; Bionics; Biosensors; Bovine serum albumin; Carbohydrates; Detectors; E coli; Effectiveness; Electrochemical impedance spectroscopy; Electrochemistry; Electrodes; Glycan; glycoprotein nano-sensing surface; Glycoproteins; Gold; Identification and classification; impedimetric biosensor; Man-BSA/Au NPs; Mannan; Mannose; Materials; Microelectrodes; microfluidic chip; Microfluidic devices; Microfluidics; Nanoparticles; Potassium; Serum albumin; Spectroscopy; Testing; China

The colonization of some bacteria to their host cell is mediated by selective adhesion between adhesin and glycan. The evaluation of antiadhesive carbohydrates in vitro has great significance in discovering new antibacterial drugs. In this paper, a microfluidic chip integrated with impedimetric neog...