Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections - Luque, S.; Grau, S.; Alvarez-Lerma, F.; Ferrández, O.; Campillo, N.; Horcajada, J.P.; Basas, M.; Lipman, J.; Roberts, J.A. (International journal of antimicrobial agents, 2014)
Keywords: Acetamides - administration & dosage; Acetamides - blood; Acetamides - cerebrospinal fluid; Acetamides - pharmacokinetics; Adult; Aged; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - blood; Anti-Bacterial Agents - cerebrospinal fluid; Anti-Bacterial Agents - pharmacokinetics; blood; Central nervous system; Central Nervous System Infections - drug therapy; Cerebrospinal fluid; Cerebrospinal Fluid - chemistry; Critical Illness; Critically ill patients; drainage; drugs; Female; Humans; Infection; Infectious Disease; linear models; Linezolid; Male; microorganisms; Middle Aged; minimum inhibitory concentration; monitoring; multiple drug resistance; Neurosurgery; Oxazolidinones - administration & dosage; Oxazolidinones - blood; Oxazolidinones - cerebrospinal fluid; Oxazolidinones - pharmacokinetics; patients; Pharmacokinetics; Plasma - chemistry; Prospective Studies; therapeutics; Linezolid; Infection; Cerebrospinal fluid; Pharmacokinetics; Central nervous system; Critically ill patients