Ectoines in cell stress protection: Uses and biotechnological production
Microorganisms produce and accumulate compatible solutes aiming at protecting themselves from environmental stresses. Among them, the wide spread in nature ectoines are receiving increasing attention by the scientific community because of their multiple applications. In fact, increasing commercial d...
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Published in | Biotechnology advances Vol. 28; no. 6; pp. 782 - 801 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Kidlington
Elsevier Inc
01.11.2010
Elsevier |
Subjects | |
Online Access | Get full text |
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Abstract | Microorganisms produce and accumulate compatible solutes aiming at protecting themselves from environmental stresses. Among them, the wide spread in nature ectoines are receiving increasing attention by the scientific community because of their multiple applications. In fact, increasing commercial demand has led to a multiplication of efforts in order to improve processes for their production.
In this review, the importance of current and potential applications of ectoines as protecting agents for macromolecules, cells and tissues, together with their potential as therapeutic agents for certain diseases are analyzed and current theories for the understanding of the molecular basis of their biological activity are discussed. The genetic, biochemical and environmental determinants of ectoines biosynthesis by natural and engineered producers are described. The major limitations of current bioprocesses used for ectoines production are discussed, with emphasis on the different microorganisms, environments, molecular engineering and fermentation strategies used to optimize the production and recovery of ectoines. The combined application of both bioprocess and metabolic engineering strategies, allowing a deeper understanding of the main factors controlling the production process is also stated. Finally, this review aims to summarize and update the state of the art in ectoines uses and applications and industrial scale production using bacteria, emphasizing the importance of reactor design and operation strategies, together with the metabolic engineering aspects and the need for feedback between
wet and
in silico work to optimize bioproduction. |
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AbstractList | Microorganisms produce and accumulate compatible solutes aiming at protecting themselves from environmental stresses. Among them, the wide spread in nature ectoines are receiving increasing attention by the scientific community because of their multiple applications. In fact, increasing commercial demand has led to a multiplication of efforts in order to improve processes for their production.
In this review, the importance of current and potential applications of ectoines as protecting agents for macromolecules, cells and tissues, together with their potential as therapeutic agents for certain diseases are analyzed and current theories for the understanding of the molecular basis of their biological activity are discussed. The genetic, biochemical and environmental determinants of ectoines biosynthesis by natural and engineered producers are described. The major limitations of current bioprocesses used for ectoines production are discussed, with emphasis on the different microorganisms, environments, molecular engineering and fermentation strategies used to optimize the production and recovery of ectoines. The combined application of both bioprocess and metabolic engineering strategies, allowing a deeper understanding of the main factors controlling the production process is also stated. Finally, this review aims to summarize and update the state of the art in ectoines uses and applications and industrial scale production using bacteria, emphasizing the importance of reactor design and operation strategies, together with the metabolic engineering aspects and the need for feedback between
wet and
in silico work to optimize bioproduction. Microorganisms produce and accumulate compatible solutes aiming at protecting themselves from environmental stresses. Among them, the wide spread in nature ectoines are receiving increasing attention by the scientific community because of their multiple applications. In fact, increasing commercial demand has led to a multiplication of efforts in order to improve processes for their production. In this review, the importance of current and potential applications of ectoines as protecting agents for macromolecules, cells and tissues, together with their potential as therapeutic agents for certain diseases are analyzed and current theories for the understanding of the molecular basis of their biological activity are discussed. The genetic, biochemical and environmental determinants of ectoines biosynthesis by natural and engineered producers are described. The major limitations of current bioprocesses used for ectoines production are discussed, with emphasis on the different microorganisms, environments, molecular engineering and fermentation strategies used to optimize the production and recovery of ectoines. The combined application of both bioprocess and metabolic engineering strategies, allowing a deeper understanding of the main factors controlling the production process is also stated. Finally, this review aims to summarize and update the state of the art in ectoines uses and applications and industrial scale production using bacteria, emphasizing the importance of reactor design and operation strategies, together with the metabolic engineering aspects and the need for feedback between wet and in silico work to optimize bioproduction. |
Author | Argandoña, Montserrat Salvador, Manuel Iborra, José L. Csonka, Laszlo N. Reina-Bueno, Mercedes Cánovas, Manuel Vargas, Carmen Nieto, Joaquín J. Pastor, José M. Bernal, Vicente |
Author_xml | – sequence: 1 givenname: José M. surname: Pastor fullname: Pastor, José M. organization: Department of Biochemistry and Molecular Biology B and Immunology, University of Murcia, Campus de Espinardo, 30100 Murcia, P.O. Box 4021, Spain – sequence: 2 givenname: Manuel surname: Salvador fullname: Salvador, Manuel organization: Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Seville, Spain – sequence: 3 givenname: Montserrat surname: Argandoña fullname: Argandoña, Montserrat organization: Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Seville, Spain – sequence: 4 givenname: Vicente surname: Bernal fullname: Bernal, Vicente organization: Department of Biochemistry and Molecular Biology B and Immunology, University of Murcia, Campus de Espinardo, 30100 Murcia, P.O. Box 4021, Spain – sequence: 5 givenname: Mercedes surname: Reina-Bueno fullname: Reina-Bueno, Mercedes organization: Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Seville, Spain – sequence: 6 givenname: Laszlo N. surname: Csonka fullname: Csonka, Laszlo N. email: csonka@purdue.edu organization: Department of Biological Sciences, Purdue University, West Lafayette, IN 47907-1392, USA – sequence: 7 givenname: José L. surname: Iborra fullname: Iborra, José L. organization: Department of Biochemistry and Molecular Biology B and Immunology, University of Murcia, Campus de Espinardo, 30100 Murcia, P.O. Box 4021, Spain – sequence: 8 givenname: Carmen surname: Vargas fullname: Vargas, Carmen email: cvargas@us.es organization: Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Seville, Spain – sequence: 9 givenname: Joaquín J. surname: Nieto fullname: Nieto, Joaquín J. organization: Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Seville, Spain – sequence: 10 givenname: Manuel surname: Cánovas fullname: Cánovas, Manuel email: mcanovas@um.es organization: Department of Biochemistry and Molecular Biology B and Immunology, University of Murcia, Campus de Espinardo, 30100 Murcia, P.O. Box 4021, Spain |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23310654$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/20600783$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1128/AEM.03136-09 10.1042/BA20000014 10.1016/S0922-338X(98)80078-0 10.1111/j.1574-6968.2007.00851.x 10.1099/00207713-51-4-1457 10.1016/S0304-4165(01)00172-6 10.1016/S0141-3910(97)00184-5 10.1007/s00792-009-0262-2 10.1016/S0021-9258(18)37550-1 10.1046/j.1365-2958.2001.02706.x 10.1128/JB.00136-06 10.1021/bp050294y 10.1128/jb.174.5.1586-1595.1992 10.1007/s007920050116 10.1111/j.1574-6976.2000.tb00542.x 10.1016/j.procbio.2008.02.003 10.1111/j.1751-1097.1997.tb08654.x 10.1074/jbc.M704023200 10.1159/000103204 10.1016/S1381-1177(99)00043-0 10.1107/S0907444903027628 10.1007/s00792-003-0372-1 10.1016/S0006-3495(85)83932-1 10.1379/1466-1268(1996)001<0023:AHSGTT>2.3.CO;2 10.1146/annurev.bioeng.4.092801.094202 10.1038/nrd1013 10.1186/1746-1448-4-12 10.1021/bi00039a051 10.1128/jb.176.17.5210-5217.1994 10.1159/000218338 10.1016/S1043-6618(03)00193-2 10.1016/S0167-7799(02)02073-5 10.1099/00221287-138-11-2473 10.1111/j.1472-765X.1996.tb01135.x 10.1002/jbm.a.30663 10.1186/1475-2859-6-31 10.1056/NEJMoa040203 10.1128/AEM.01698-08 10.1128/jb.174.15.5027-5035.1992 10.1111/j.1574-6968.1993.tb06497.x 10.1016/j.clindermatol.2008.01.002 10.1007/s00253-009-2036-2 10.1074/jbc.274.11.6920 10.1128/AEM.65.9.3774-3779.1999 10.1016/S0896-6273(00)81132-0 10.1128/JB.187.4.1293-1304.2005 10.1071/EN06016 10.1111/j.1432-1033.1985.tb08903.x 10.1016/0005-2736(77)90320-0 10.1128/AEM.68.2.772-783.2002 10.1128/AEM.00768-08 10.1128/AEM.46.1.152-159.1983 10.1128/AEM.02482-06 10.1016/S0168-9525(98)01559-5 10.1128/.61.1.90-104.1997 10.1016/S0021-9258(19)68947-7 10.1128/MMBR.63.2.334-348.1999 10.1099/00221287-139-1-129 10.1016/j.bbrc.2004.07.200 10.1099/00221287-136-4-705 10.1093/ps/79.5.748 10.1159/000080216 10.1016/0014-5793(95)00514-A 10.1007/s00253-006-0553-9 10.1016/0140-6736(90)90275-A 10.1016/S0014-5793(04)00326-6 10.2527/2000.783668x 10.1046/j.1523-1747.2003.12148.x 10.1111/j.1574-6968.2002.tb11227.x 10.1007/s00792-002-0286-3 10.1046/j.1462-2920.2001.00252.x 10.1111/j.1574-6968.1996.tb08430.x 10.1111/j.1462-2920.2007.01494.x 10.1021/bi020316e 10.1073/pnas.77.5.2777 10.1021/jp068367z 10.1186/1743-8977-2-10 10.1007/BF00174204 10.1002/1439-7633(20020503)3:5<384::AID-CBIC384>3.0.CO;2-H 10.1016/j.resmic.2006.03.004 10.1111/j.1600-0781.2006.00188.x 10.1111/j.1365-4632.2004.02222.x 10.1128/MMBR.54.4.432-449.1990 10.1016/j.plantsci.2005.08.019 10.1128/JB.184.11.3078-3085.2002 10.1002/bit.22750 10.1021/bp0500967 10.1016/S0141-0229(97)00063-X 10.1515/BC.2002.101 10.1074/jbc.274.46.33105 10.1242/jeb.01730 10.1128/MMBR.00024-09 10.1016/j.jbiotec.2010.03.003 10.1007/BF00409756 10.1016/j.nbd.2005.02.011 10.1042/bj2670125 10.1111/j.1574-6968.1990.tb03815.x 10.1128/AEM.68.9.4328-4333.2002 10.1016/j.jmb.2006.11.067 10.1086/302269 10.1073/pnas.87.22.8985 10.1104/pp.122.4.1239 10.1128/AEM.70.5.3143-3145.2004 10.1186/1746-1448-1-5 10.1203/00006450-198107000-00008 10.1067/mjd.2001.114594 10.1128/MMBR.38.3.272-290.1974 10.1074/jbc.274.22.15345 10.1007/BF00456848 10.1016/j.biotechadv.2005.04.004 10.1074/jbc.R700042200 10.1111/j.0022-202X.2005.23782.x 10.1006/jmbi.2001.4819 10.1111/j.1472-765X.2007.02156.x 10.1016/0168-1656(95)00119-2 10.1099/00221287-143-4-1141 10.1128/AEM.70.5.3130-3132.2004 10.1111/j.1365-2672.2005.02757.x 10.1089/cpt.2006.9996 10.1089/ars.2007.1897 10.1016/j.jphotobiol.2008.01.008 10.1097/00006534-196508000-00013 10.1263/jbb.102.560 10.1016/j.jaad.2005.05.010 10.1111/j.1365-3040.2005.01410.x 10.1099/mic.0.27122-0 10.2741/roberts 10.1007/s00383-004-1321-5 10.1016/0141-0229(86)90080-3 10.1128/AEM.66.4.1572-1579.2000 10.1002/bit.21619 10.1016/0011-2240(90)90023-W 10.1016/S0300-9629(96)00275-7 10.1379/CSC-101R.1 10.1016/S0168-1605(02)00388-4 10.1007/s002530051459 10.1016/S0092-8674(03)01031-6 10.1007/BF00167285 10.1164/rccm.200812-1911OC 10.1016/S0923-1811(99)00077-8 10.1016/S0723-2020(98)80060-X 10.1186/1472-6750-7-82 10.1128/MMBR.62.2.504-544.1998 10.1007/s10529-008-9688-3 10.1016/S1389-1723(01)80136-5 10.1128/AEM.68.1.93-101.2002 10.1073/pnas.0308633101 10.1111/j.1574-6968.2004.tb09502.x 10.1073/pnas.95.16.9268 10.1128/AEM.69.10.5919-5927.2003 10.1038/nbt0105-40 10.1074/jbc.272.41.25794 10.1073/pnas.90.23.10962 10.1007/s002530051412 10.1186/1746-1448-4-6 10.1016/j.molcatb.2009.09.014 10.1016/j.cplett.2004.02.104 10.1146/annurev.biochem.66.1.385 10.1016/S0921-8777(98)00029-9 10.1046/j.1365-2958.1998.00875.x 10.1007/s00792-008-0142-1 10.1016/S1389-1723(02)80213-4 10.1038/362543a0 10.1002/j.1460-2075.1990.tb07637.x 10.1016/j.bbrc.2007.11.074 10.1016/S0376-7388(02)00539-2 10.1002/3527600035.bpol7007 10.1021/bi970247h 10.1016/0011-2240(82)90159-6 10.1046/j.1365-2133.2001.04010.x 10.1007/BF00245273 10.1007/s00792-004-0375-6 10.1016/j.bbapap.2006.04.015 10.1080/00327488808062543 10.1111/j.1445-2197.1998.tb02099.x 10.1016/S0968-0004(98)01350-4 10.1101/gad.4.8.1365 10.1002/(SICI)1097-0290(19980205)57:3<306::AID-BIT7>3.0.CO;2-L 10.1016/j.ccm.2007.06.008 10.1007/s007920100212 10.1016/j.febslet.2005.07.057 10.1128/jb.178.2.385-395.1996 |
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References | Cruz, Silva, Roldao, Carmo, Carrondo, Alves (bb0215) 2006; 22 Frings, Sauer, Galinski (bb0280) 1995; 43 Inbar, Lapidot (bb0385) 1988; 263 Schiraldi, Maresca, Catapano, Galinski, De Rosa (bb0805) 2006; 157 Schwamborn (bb0830) 1998; 59 Motitschke (LH, DE), Driller, Hansjurgen (Monheim, DE), Galinski, Erwin (Bonn, DE); Merck Patent GmbH (DE), assignee. 2000. Ectoin and ectoin derivatives as moisturizers in cosmetics. United States. Canovas, Vargas, Calderon, Ventosa, Nieto (bb0180) 1998; 21 Guzman, Van-Thuoc, Martin, Hatti-Kaul, Quillaguaman (bb0355) 2009; 84 Botta, Di Giorgio, Sabatier, De Meo (bb0110) 2008; 91 Wang, Bolen (bb0925) 1997; 36 Sideris, Papageorgiou, Charalampous, Vitsa (bb0845) 1981; 15 Yu, Jindo, Nagaoka (bb0965) 2007; 111 Saum, Müller (bb0795) 2008; 10 Nakayama, Yoshida, Ono, Murooka, Shinmyo (bb0625) 2000; 122 Knapp, Ladenstein, Galinski (bb0435) 1999; 3 Naughton, Blumerman, Carlberg, Boyd (bb0630) 2009; 75 Paulson (bb0675) 1999; 64 Bunger (bb0140) 1999; 7 Poolman, Glaasker (bb0710) 1998; 29 Fischel, Oren (bb0260) 1993; 113 Gonzalez-Ulloa, Flores (bb0325) 1965; 36 Nagata, Wang, Oshima, Zhang, Miyake, Sasaki (bb0615) 2008; 99 Burg, Ferraris (bb0150) 2008; 283 Oren, Heldal, Norland, Galinski (bb0665) 2002; 6 release from cells, esp. microorganisms, following application of stress patent DE4244580-A. Bursy, Kuhlmann, Pittelkow, Hartmann, Jebbar, Pierik (bb0155) 2008; 74 Qu, Bolen, Bolen (bb0725) 1998; 95 Sydlik, Gallitz, Albrecht, Abel, Krutmann, Unfried (bb0860) 2009; 180 Van-Thuoc, Guzman, Guillaguaman, Hatti-Kaul (bb0900) 2010; 147 Sauer, Galinski (bb0790) 1998; 57 Talibart, Jebbar, Gouesbet, Himdikabbab, Wroblewski, Blanco (bb0865) 1994; 176 Louis, Galinski (bb0535) 1997; 143 da Costa, Santos, Galinski, Antranikian (bb0220) 1998; 61 Calderon, Vargas, Rojo, Iglesias-Guerra, Csonka, Ventosa (bb0165) 2004; 150 Schroder, Wagner (bb0820) 2002; 383 Souil, Capon, Mordon, Dinh-Xuan, Polla, Bachelet (bb0850) 2001; 144 Roessler, Müller (bb0775) 2001; 3 Berneburg, Grether-Beck, Kurten, Ruzicka, Briviba, Sies (bb0080) 1999; 274 Bestvater, Galinski (bb0090) 2002; 6 Clegg, Seitz, Seitz, Hazlewood (bb0200) 1982; 19 Koichi M, Mitsuhiko M, Tatsuo N, Yoshio S; Takeda Chem Ind Ltd (Take), assignee. 1991. Preparation of tetrahydropyrimidine derivatives used for medical agent, etc., by reacting e.g. acetonitrile with e.g. methyl 2,4-diaminobutyrate. Japan patent JP3031265-A. Nagata, Maekawa, Ikeuchi, Wang, Ishida (bb0610) 2002; 94 Stahl, Roneker, Thornton, Lei (bb0855) 2000; 78 Wei, Wedeking, Buttner, Kalff, Tolba, van Echten-Deckert (bb0940) 2009; 76 Tavaria, Gabriele, Kola, Anderson (bb0870) 1996; 1 Galinski, Pfeiffer, Trüper (bb0295) 1985; 149 Nagata, Wang (bb0620) 2001; 91 Ullah (bb0895) 1988; 18 Maskow, Kleinsteuber (bb0585) 2004; 8 Welsh (bb0945) 2000; 24 Tsapis, Kepes (bb0890) 1977; 469 Buenger, Driller (bb0135) 2004; 17 Giannessi, Caselli, Vitale, Crucean, Murzi, Del Ry (bb0315) 2003; 48 Pflughoeft, Kierek, Watnick (bb0705) 2003; 69 Galinski, Herzog (bb0290) 1990; 153 Fligiel, Varani, Datta, Kang, Fisher, Voorhees (bb0265) 2003; 120 Malin, Iakobashvili, Lapidot (bb0550) 1999; 274 Buenger, Degwert, Driller (bb0130) 2001; 4 Andersson, Breccia, Hatti-Kaul (bb0010) 2000; 32 Onraedt, Walcarius, Soetaert, Vandamme (bb0655) 2005; 21 Argandoña, Nieto, Iglesias-Guerra, Calderón, García-Estepa, Vargas (bb0025) 2010; 76 Arora, Ha, Park (bb0030) 2004; 564 Buommino, Schiraldi, Baroni, Paoletti, Lamberti, De Rosa (bb0145) 2005; 10 Shiloach, Fass (bb0840) 2005; 23 Leung, Rajendran, Monfries, Hall, Lim (bb0510) 1990; 267 Kanapathipillai, Ku, Girigoswami, Park (bb0415) 2008; 365 Mascellani, Liu, Rossi, Marchesini, Valentini, Arcelli (bb0575) 2007; 7 Yu, Nagaoka (bb0970) 2004; 388 Peters, von Klot, Heier, Trentinaglia, Hormann, Wichmann (bb0685) 2004; 351 Manzanera, Vilchez, Tunnacliffe (bb0570) 2004; 70 Crowe, Carpenter, Crowe, Anchordoguy (bb0210) 1990; 43 Jeffries (bb0400) 2005; 23 Schnoor, Voss, Cullen, Boking, Galla, Galinski (bb0815) 2004; 322 Moghaieb, Tanaka, Saneoka, Murooka, Ono, Morikawa (bb0590) 2006; 29 Bernard, Jebbar, Rassouli, Himdikabbab, Hamelin, Blanco (bb0070) 1993; 139 Manzanera, Vilchez, Tunnacliffe (bb0565) 2004; 233 Bersch, Vangala, Schwarz, Kaufmann (bb0085) 2000 Lentzen, Schwarz (bb0500) 2006; 72 Tolmasoff, Ono, Cutler (bb0885) 1980; 77 Lizuka, Ishida-Yamamoto, Kajita, Tsutsui, Ohkuma (bb0525) 1988; 280 Göller, Galinski (bb0320) 1999; 7 Zhang, Lang, Nagata (bb0985) 2009; 13 Schiraldi, De Rosa (bb0800) 2002; 20 Donaldson, Tran, Jimenez, Duffin, Newby, Mills (bb0240) 2005; 2 Rajan, Joseph, Thampuran, James, Kumar, Viswanathan (bb0740) 2008; 30 Krutmann (bb0460) 2003 Wiggins (bb0950) 1990; 54 Zhang, Lang, Wang, Nagata (bb0975) 2008; 43 Lanyi (bb0480) 1974; 38 Bremer, Krämer (bb0115) 2000 Lapidot A, Iakobashvili R, Malin G; Yeda Res & Dev Co Ltd (Yeda) Yeda Res&Dev Co Ltd (Yeda), assignee. 1999. Performing nucleic acid extension reaction in presence of osmoprotectant, e.g. proline, particularly for sequencing and amplification — increases stability of polymerase and reduces melting temperature of template or primer. Patent WO9941410-A; EP1053350-A; WO9941410-A1; EP1053350-A1; JP2002503482-W; US6428986-B1; IL137725-A; US7150980-B1; US2007212760-A1; US7387878-B2; EP1053350-B1; DE69940662-E; ES2323561-T3; JP4393700-B2. Wohlfarth, Severin, Galinski (bb0955) 1990; 136 Rai, Pal, Sumesh, Jain, Sankaranarayanan (bb0735) 2006; 170 Vargas, Jebbar, Carrasco, Blanco, Calderon, Iglesias-Guerra (bb0910) 2006; 100 Rabe, Mamelak, McElgunn, Morison, Sauder (bb0730) 2006; 55 Grether-Beck, Timmer, Felsner, Brenden, Brammertz, Krutmann (bb0350) 2005; 125 Fernandez-Linares, Faure, Bertrand, Gauthier (bb0250) 1996; 22 Lippert, Galinski (bb0515) 1992; 37 Lo, Bonner, Xie, D'Souza, Jensen (bb0530) 2009; 73 Jebbar, Sohn-Bosser, Bremer, Bernard, Blanco (bb0390) 2005; 187 Kanapathipillai, Lentzen, Sierks, Park (bb0420) 2005; 579 Canovas, Maiquez, De Diego, Buendia, Espinosa, Iborra (bb0190) 2003; 214 Omata, Lewis, Rotenberg, Lockwood, Messer, Noda (bb0645) 2006; 77 Pul, Wurm, Wagner (bb0720) 2007; 366 Timasheff (bb0880) 2002; 41 Brown (bb0125) 1990 Galinski EA, Trueper H, Sauer T, Trueper HG, Trüper HG, Galinski E; Bitop Ges Biotechnische Optimierung MBH assignee. 1994. Prodn. of natural substances, e.g. new hydroxy:ectoin deriv — by Bursy, Pierik, Pica, Bremer (bb0160) 2007; 282 Canovas, Vargas, Iglesias-Guerra, Csonka, Rhodes, Ventosa (bb0185) 1997; 272 Bestvater, Louis, Galinski (bb0095) 2008; 4 Heinrich, Garbe, Tronnier (bb0380) 2007; 20 Peters, Galinski, Trüper (bb0690) 1990; 71 Lee, Timasheff (bb0495) 1981; 256 Riesenberg, Guthke (bb0755) 1999; 51 Grammel (bb0340) 2000 Wang, Zhang (bb0935) 2010; 62 Pfluecker, Bunger, Hitzel, Witte, Beck, Lergenmuller (bb0700) 2005; 131 Kanias, Acker (bb0425) 2006; 4 Pan, Baldwin, Nguyen, Gasset, Serban, Groth (bb0670) 1993; 90 Maskow, Babel (bb0580) 2001; 1528 Zhang, Wang, Zhang, Wang, Zhu, Wang (bb0980) 2006; 102 Kakizuka (bb0410) 1998; 14 Cordingley, LaFemina, Callahan, Condra, Sardana, Graham (bb0205) 1990; 87 Obon, Maiquez, Canovas, Kleber, Iborra (bb0640) 1999; 51 Galinski, Stein, Amendt, Kinder (bb0300) 1997; 117A Berneburg, Gattermann, Stege, Grewe, Vogelsang, Ruzicka (bb0075) 1997; 66 Roberts (bb0770) 2005; 1 Hai, Oppermann-Sanio, Steinbuchel (bb0360) 2002; 68 Louis, Trüper, Galinski (bb0540) 1994; 41 Kuhlmann, Bremer (bb0465) 2002; 68 Schubert, Maskow, Benndorf, Harms, Breuer (bb0825) 2007; 73 Oren (bb0660) 1999; 63 Lapidot, Ben-Asher, Eisenstein (bb0485) 1995; 367 Tetsch, Kunte (bb0875) 2002; 211 Cayley, Lewis, Record (bb0195) 1992; 174 Murphy (bb0605) 2002; 4 Kunte (bb0470) 2006; 3 Obon, Maiquez, Canovas, Kleber, Iborra (bb0635) 1997; 21 Canamas, Vinas, Usall, Magan, Morello, Teixido (bb0170) 2007; 45 Krutmann (bb0455) 2000; 23 Arahal, Garcia, Vargas, Canovas, Nieto, Ventosa (bb0015) 2001; 51 Bringardner, Baran, Eubank, Marsh (bb0120) 2008; 10 Liu, Bolen (bb0520) 1995; 3 Graf, Anzali, Buenger, Pfluecker, Driller (bb0330) 2008; 26 Harper, Lansbury (bb0370) 1997; 66 Wang, Setlow, Berwick, Polsky, Marghoob, Kopf (bb0930) 2001; 44 He, Huang, Gu, Jiang, Li (bb0375) 2006; 46 Dingwall, Ernberg, Gait, Green, Heaphy, Karn (bb0230) 1990; 9 Yancey (bb0960) 2005; 208 Aston, Peyton (bb0035) 2007; 274 Pflaum, Kielbassa, Garmyn, Epe (bb0695) 1998; 408 Dobson (bb0235) 2003; 2 Morbach, Krämer (bb0595) 2002; 3 Canovas, Borges, Vargas, Ventosa, Nieto, Santos (bb0175) 1999; 65 Furusho, Yoshizawa, Shoji (bb0285) 2005; 20 Grant, Wall, Mimeault, Zhong, Ghent, Garcia (bb0345) 1990; 335 Kolp, Pietsch, Galinski, Gutschow (bb0445) 2006; 1764 Beyer, Driller, Bunger (bb0100) 2000; 126 Sander, Chang, Hamm, Elsner, Thiele (bb0785) 2004; 43 Malin, Lapidot (bb0555) 1996; 178 Vermeulen, Kunte (bb0920) 2004; 8 Reed, Warr, Kerby, Stewart (bb0750) 1986; 8 Arakawa, Timasheff (bb0020) 1985; 47 Kong, Blennerhassett, Heel, McCauley, Hall (bb0450) 1998; 68 Jebbar, Talibart, Gloux, Bernard, Blanco (bb0395) 1992; 174 Bernal, Sevilla, Canovas, Iborra (bb0065) 2007; 6 Garcia-Estepa, Argandoña, Reina-Bueno, Capote, Iglesias-Guerra, Nieto (bb0310) 2006; 188 Dennis, Shimmin (bb0225) 1997; 61 Keshavarz (bb0430) 2000; 79 Azam, Ishihama (bb0040) 1999; 274 Manzanera, de Castro, Tondervik, Rayner-Brandes, Strom, Tunnacliffe (bb0560) 2002; 68 Fourtanier, Bernerd, Bouillon, Marrot, Moyal, Seite (bb0275) 2006; 22 Roberts (bb0765) 2000; 5 Van-Thuoc, Guzman, Thi-Hang, Hatti-Kaul (bb0905) 2009 Raymond, Sistrom (bb0745) 1969; 69 Schmitz, Galinski (bb0810) 1996; 142 Banciu, Sorokin, Tourova, Galinski, Muntyan, Kuenen (bb0050) 2008; 12 Perutz (bb0680) 1999; 24 Severin, Wohlfarth, Galinski (bb0835) 1992; 138 Baliarda, Robert, Jebbar, Blanco, Deschamps, Le Marrec (bb0045) 2003; 84 Kurz (bb0475) 2008; 4 Zou, Hernandez, Burgos, Martinez, Gonzalez-Reyes, Fernandez-Dumont (bb0990) 2005; 21 Ono, Okuda, Tongpim, Imai, Shinmyo, Sakuda (bb0650) 1998; 85 Bennion, Daggett (bb0060) 2004; 101 Grammam, Volke, Kunte (bb0335) 2002; 184 Prabhu, Schauwecker, Grammel, Keller, Bernhardt (bb0715) 2004; 70 Bolen, Baskakov (bb0105) 2001; 310 Forloni, Angeretti, Chiesa, Monzani, Salmona, Bugiani (bb0270) 1993; 362 Le Rudulier, Bouillard (bb0505) 1983 Yu (10.1016/j.biotechadv.2010.06.005_bb0970) 2004; 388 Pflughoeft (10.1016/j.biotechadv.2010.06.005_bb0705) 2003; 69 Buenger (10.1016/j.biotechadv.2010.06.005_bb0130) 2001; 4 Wohlfarth (10.1016/j.biotechadv.2010.06.005_bb0955) 1990; 136 Schroder (10.1016/j.biotechadv.2010.06.005_bb0820) 2002; 383 da Costa (10.1016/j.biotechadv.2010.06.005_bb0220) 1998; 61 Tavaria (10.1016/j.biotechadv.2010.06.005_bb0870) 1996; 1 Schubert (10.1016/j.biotechadv.2010.06.005_bb0825) 2007; 73 Beyer (10.1016/j.biotechadv.2010.06.005_bb0100) 2000; 126 Pflaum (10.1016/j.biotechadv.2010.06.005_bb0695) 1998; 408 Kolp (10.1016/j.biotechadv.2010.06.005_bb0445) 2006; 1764 Maskow (10.1016/j.biotechadv.2010.06.005_bb0580) 2001; 1528 Ventosa (10.1016/j.biotechadv.2010.06.005_bb0915) 1998; 62 Tetsch (10.1016/j.biotechadv.2010.06.005_bb0875) 2002; 211 Wiggins (10.1016/j.biotechadv.2010.06.005_bb0950) 1990; 54 Morbach (10.1016/j.biotechadv.2010.06.005_bb0595) 2002; 3 Wang (10.1016/j.biotechadv.2010.06.005_bb0935) 2010; 62 Oren (10.1016/j.biotechadv.2010.06.005_bb0665) 2002; 6 Yancey (10.1016/j.biotechadv.2010.06.005_bb0960) 2005; 208 Bernal (10.1016/j.biotechadv.2010.06.005_bb0065) 2007; 6 Canovas (10.1016/j.biotechadv.2010.06.005_bb0190) 2003; 214 Grammel (10.1016/j.biotechadv.2010.06.005_bb0340) 2000 Barth (10.1016/j.biotechadv.2010.06.005_bb0055) 2000; 66 Onraedt (10.1016/j.biotechadv.2010.06.005_bb0655) 2005; 21 Lanyi (10.1016/j.biotechadv.2010.06.005_bb0480) 1974; 38 Jebbar (10.1016/j.biotechadv.2010.06.005_bb0390) 2005; 187 Ferrigno (10.1016/j.biotechadv.2010.06.005_bb0255) 2000; 26 Pfluecker (10.1016/j.biotechadv.2010.06.005_bb0700) 2005; 131 Zhang (10.1016/j.biotechadv.2010.06.005_bb0980) 2006; 102 Sauer (10.1016/j.biotechadv.2010.06.005_bb0790) 1998; 57 Bunger (10.1016/j.biotechadv.2010.06.005_bb0140) 1999; 7 Bestvater (10.1016/j.biotechadv.2010.06.005_bb0090) 2002; 6 10.1016/j.biotechadv.2010.06.005_bb0405 Obon (10.1016/j.biotechadv.2010.06.005_bb0635) 1997; 21 Lee (10.1016/j.biotechadv.2010.06.005_bb0495) 1981; 256 Kanias (10.1016/j.biotechadv.2010.06.005_bb0425) 2006; 4 Rai (10.1016/j.biotechadv.2010.06.005_bb0735) 2006; 170 Lizuka (10.1016/j.biotechadv.2010.06.005_bb0525) 1988; 280 Timasheff (10.1016/j.biotechadv.2010.06.005_bb0880) 2002; 41 Canamas (10.1016/j.biotechadv.2010.06.005_bb0170) 2007; 45 Tsapis (10.1016/j.biotechadv.2010.06.005_bb0890) 1977; 469 Malin (10.1016/j.biotechadv.2010.06.005_bb0550) 1999; 274 Roessler (10.1016/j.biotechadv.2010.06.005_bb0775) 2001; 3 Zhang (10.1016/j.biotechadv.2010.06.005_bb0985) 2009; 13 Dennis (10.1016/j.biotechadv.2010.06.005_bb0225) 1997; 61 Dobson (10.1016/j.biotechadv.2010.06.005_bb0235) 2003; 2 Wang (10.1016/j.biotechadv.2010.06.005_bb0925) 1997; 36 Fernandez-Linares (10.1016/j.biotechadv.2010.06.005_bb0250) 1996; 22 Lo (10.1016/j.biotechadv.2010.06.005_bb0530) 2009; 73 Burg (10.1016/j.biotechadv.2010.06.005_bb0150) 2008; 283 He (10.1016/j.biotechadv.2010.06.005_bb0375) 2006; 46 Van-Thuoc (10.1016/j.biotechadv.2010.06.005_bb0905) 2009 Grether-Beck (10.1016/j.biotechadv.2010.06.005_bb0350) 2005; 125 Bremer (10.1016/j.biotechadv.2010.06.005_bb0115) 2000 Omata (10.1016/j.biotechadv.2010.06.005_bb0645) 2006; 77 Bestvater (10.1016/j.biotechadv.2010.06.005_bb0095) 2008; 4 Tolmasoff (10.1016/j.biotechadv.2010.06.005_bb0885) 1980; 77 Giannessi (10.1016/j.biotechadv.2010.06.005_bb0315) 2003; 48 Peters (10.1016/j.biotechadv.2010.06.005_bb0685) 2004; 351 Baliarda (10.1016/j.biotechadv.2010.06.005_bb0045) 2003; 84 Keshavarz (10.1016/j.biotechadv.2010.06.005_bb0430) 2000; 79 Poolman (10.1016/j.biotechadv.2010.06.005_bb0710) 1998; 29 Shiloach (10.1016/j.biotechadv.2010.06.005_bb0840) 2005; 23 Macnee (10.1016/j.biotechadv.2010.06.005_bb0545) 2007; 28 Manzanera (10.1016/j.biotechadv.2010.06.005_bb0570) 2004; 70 Kunte (10.1016/j.biotechadv.2010.06.005_bb0470) 2006; 3 Krutmann (10.1016/j.biotechadv.2010.06.005_bb0455) 2000; 23 Banciu (10.1016/j.biotechadv.2010.06.005_bb0050) 2008; 12 Gonzalez-Ulloa (10.1016/j.biotechadv.2010.06.005_bb0325) 1965; 36 Leung (10.1016/j.biotechadv.2010.06.005_bb0510) 1990; 267 Nagata (10.1016/j.biotechadv.2010.06.005_bb0620) 2001; 91 Arora (10.1016/j.biotechadv.2010.06.005_bb0030) 2004; 564 Bringardner (10.1016/j.biotechadv.2010.06.005_bb0120) 2008; 10 Canovas (10.1016/j.biotechadv.2010.06.005_bb0180) 1998; 21 Murphy (10.1016/j.biotechadv.2010.06.005_bb0605) 2002; 4 Schnoor (10.1016/j.biotechadv.2010.06.005_bb0815) 2004; 322 Crowe (10.1016/j.biotechadv.2010.06.005_bb0210) 1990; 43 Sydlik (10.1016/j.biotechadv.2010.06.005_bb0860) 2009; 180 10.1016/j.biotechadv.2010.06.005_bb0600 Göller (10.1016/j.biotechadv.2010.06.005_bb0320) 1999; 7 Prabhu (10.1016/j.biotechadv.2010.06.005_bb0715) 2004; 70 Malin (10.1016/j.biotechadv.2010.06.005_bb0555) 1996; 178 Aguzzi (10.1016/j.biotechadv.2010.06.005_bb0005) 2004; 116 Heinrich (10.1016/j.biotechadv.2010.06.005_bb0380) 2007; 20 Lentzen (10.1016/j.biotechadv.2010.06.005_bb0500) 2006; 72 Brown (10.1016/j.biotechadv.2010.06.005_bb0125) 1990 Moghaieb (10.1016/j.biotechadv.2010.06.005_bb0590) 2006; 29 Qu (10.1016/j.biotechadv.2010.06.005_bb0725) 1998; 95 Bursy (10.1016/j.biotechadv.2010.06.005_bb0155) 2008; 74 Manzanera (10.1016/j.biotechadv.2010.06.005_bb0565) 2004; 233 Cruz (10.1016/j.biotechadv.2010.06.005_bb0215) 2006; 22 Nagata (10.1016/j.biotechadv.2010.06.005_bb0615) 2008; 99 Obon (10.1016/j.biotechadv.2010.06.005_bb0640) 1999; 51 Liu (10.1016/j.biotechadv.2010.06.005_bb0520) 1995; 3 Canovas (10.1016/j.biotechadv.2010.06.005_bb0185) 1997; 272 Harjes (10.1016/j.biotechadv.2010.06.005_bb0365) 2004; 60 Mascellani (10.1016/j.biotechadv.2010.06.005_bb0575) 2007; 7 Riesenberg (10.1016/j.biotechadv.2010.06.005_bb0755) 1999; 51 Bernard (10.1016/j.biotechadv.2010.06.005_bb0070) 1993; 139 Stahl (10.1016/j.biotechadv.2010.06.005_bb0855) 2000; 78 Welsh (10.1016/j.biotechadv.2010.06.005_bb0945) 2000; 24 Bursy (10.1016/j.biotechadv.2010.06.005_bb0160) 2007; 282 Bennion (10.1016/j.biotechadv.2010.06.005_bb0060) 2004; 101 Roberts (10.1016/j.biotechadv.2010.06.005_bb0765) 2000; 5 Lippert (10.1016/j.biotechadv.2010.06.005_bb0515) 1992; 37 Galinski (10.1016/j.biotechadv.2010.06.005_bb0295) 1985; 149 Inbar (10.1016/j.biotechadv.2010.06.005_bb0385) 1988; 263 Manzanera (10.1016/j.biotechadv.2010.06.005_bb0560) 2002; 68 Pul (10.1016/j.biotechadv.2010.06.005_bb0720) 2007; 366 Le Rudulier (10.1016/j.biotechadv.2010.06.005_bb0505) 1983; 46 Kurz (10.1016/j.biotechadv.2010.06.005_bb0475) 2008; 4 Maskow (10.1016/j.biotechadv.2010.06.005_bb0585) 2004; 8 Nagata (10.1016/j.biotechadv.2010.06.005_bb0610) 2002; 94 Krutmann (10.1016/j.biotechadv.2010.06.005_bb0460) 2003 Zou (10.1016/j.biotechadv.2010.06.005_bb0990) 2005; 21 Souil (10.1016/j.biotechadv.2010.06.005_bb0850) 2001; 144 Hai (10.1016/j.biotechadv.2010.06.005_bb0360) 2002; 68 Bolen (10.1016/j.biotechadv.2010.06.005_bb0105) 2001; 310 Donaldson (10.1016/j.biotechadv.2010.06.005_bb0240) 2005; 2 Azam (10.1016/j.biotechadv.2010.06.005_bb0040) 1999; 274 Schmitz (10.1016/j.biotechadv.2010.06.005_bb0810) 1996; 142 Zhang (10.1016/j.biotechadv.2010.06.005_bb0975) 2008; 43 Jeffries (10.1016/j.biotechadv.2010.06.005_bb0400) 2005; 23 Severin (10.1016/j.biotechadv.2010.06.005_bb0835) 1992; 138 Lapidot (10.1016/j.biotechadv.2010.06.005_bb0485) 1995; 367 Buommino (10.1016/j.biotechadv.2010.06.005_bb0145) 2005; 10 Kong (10.1016/j.biotechadv.2010.06.005_bb0450) 1998; 68 Oren (10.1016/j.biotechadv.2010.06.005_bb0660) 1999; 63 10.1016/j.biotechadv.2010.06.005_bb0490 Canovas (10.1016/j.biotechadv.2010.06.005_bb0175) 1999; 65 Andersson (10.1016/j.biotechadv.2010.06.005_bb0010) 2000; 32 Arahal (10.1016/j.biotechadv.2010.06.005_bb0015) 2001; 51 Graf (10.1016/j.biotechadv.2010.06.005_bb0330) 2008; 26 Yu (10.1016/j.biotechadv.2010.06.005_bb0965) 2007; 111 Fligiel (10.1016/j.biotechadv.2010.06.005_bb0265) 2003; 120 Ono (10.1016/j.biotechadv.2010.06.005_bb0650) 1998; 85 Rajan (10.1016/j.biotechadv.2010.06.005_bb0740) 2008; 30 Talibart (10.1016/j.biotechadv.2010.06.005_bb0865) 1994; 176 Louis (10.1016/j.biotechadv.2010.06.005_bb0535) 1997; 143 Louis (10.1016/j.biotechadv.2010.06.005_bb0540) 1994; 41 Sander (10.1016/j.biotechadv.2010.06.005_bb0785) 2004; 43 Fallet (10.1016/j.biotechadv.2010.06.005_bb0245) 2010; 107 Kanapathipillai (10.1016/j.biotechadv.2010.06.005_bb0415) 2008; 365 Wang (10.1016/j.biotechadv.2010.06.005_bb0930) 2001; 44 Berneburg (10.1016/j.biotechadv.2010.06.005_bb0080) 1999; 274 Peters (10.1016/j.biotechadv.2010.06.005_bb0690) 1990; 71 Sideris (10.1016/j.biotechadv.2010.06.005_bb0845) 1981; 15 Roberts (10.1016/j.biotechadv.2010.06.005_bb0770) 2005; 1 Knapp (10.1016/j.biotechadv.2010.06.005_bb0435) 1999; 3 Calderon (10.1016/j.biotechadv.2010.06.005_bb0165) 2004; 150 Aston (10.1016/j.biotechadv.2010.06.005_bb0035) 2007; 274 Kanapathipillai (10.1016/j.biotechadv.2010.06.005_bb0420) 2005; 579 Pan (10.1016/j.biotechadv.2010.06.005_bb0670) 1993; 90 Van-Thuoc (10.1016/j.biotechadv.2010.06.005_bb0900) 2010; 147 10.1016/j.biotechadv.2010.06.005_bb0305 Perutz (10.1016/j.biotechadv.2010.06.005_bb0680) 1999; 24 Wei (10.1016/j.biotechadv.2010.06.005_bb0940) 2009; 76 Berneburg (10.1016/j.biotechadv.2010.06.005_bb0075) 1997; 66 Raymond (10.1016/j.biotechadv.2010.06.005_bb0745) 1969; 69 Argandoña (10.1016/j.biotechadv.2010.06.005_bb0025) 2010; 76 Kuhlmann (10.1016/j.biotechadv.2010.06.005_bb0465) 2002; 68 Cayley (10.1016/j.biotechadv.2010.06.005_bb0195) 1992; 174 Bersch (10.1016/j.biotechadv.2010.06.005_bb0085) 2000 Jebbar (10.1016/j.biotechadv.2010.06.005_bb0395) 1992; 174 Galinski (10.1016/j.biotechadv.2010.06.005_bb0300) 1997; 117A Kakizuka (10.1016/j.biotechadv.2010.06.005_bb0410) 1998; 14 Fischel (10.1016/j.biotechadv.2010.06.005_bb0260) 1993; 113 Vermeulen (10.1016/j.biotechadv.2010.06.005_bb0920) 2004; 8 10.1016/j.biotechadv.2010.06.005_bb0440 Forloni (10.1016/j.biotechadv.2010.06.005_bb0270) 1993; 362 Rabe (10.1016/j.biotechadv.2010.06.005_bb0730) 2006; 55 Naughton (10.1016/j.biotechadv.2010.06.005_bb0630) 2009; 75 Saum (10.1016/j.biotechadv.2010.06.005_bb0795) 2008; 10 Arakawa (10.1016/j.biotechadv.2010.06.005_bb0020) 1985; 47 Dingwall (10.1016/j.biotechadv.2010.06.005_bb0230) 1990; 9 Harper (10.1016/ |
References_xml | – volume: 120 start-page: 842 year: 2003 end-page: 848 ident: bb0265 article-title: Collagen degradation in aged/photodamaged skin publication-title: J Invest Dermatol contributor: fullname: Voorhees – volume: 2 start-page: 10 year: 2005 end-page: 19 ident: bb0240 article-title: Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure publication-title: Part Fibre Toxicol contributor: fullname: Mills – volume: 274 start-page: 33105 year: 1999 end-page: 33113 ident: bb0040 article-title: Twelve species of the nucleoid-associated protein from publication-title: J Biol Chem contributor: fullname: Ishihama – volume: 51 start-page: 760 year: 1999 end-page: 764 ident: bb0640 article-title: High-density publication-title: Appl Microbiol Biotechnol contributor: fullname: Iborra – volume: 68 start-page: 4328 year: 2002 end-page: 4333 ident: bb0560 article-title: Hydroxyectoine is superior to trehalose for anhydrobiotic engineering of publication-title: Appl Environ Microbiol contributor: fullname: Tunnacliffe – volume: 24 start-page: 58-3 year: 1999 ident: bb0680 article-title: Glutamine repeats and neurodegenerative diseases: molecular aspects publication-title: Trends Biochem Sci contributor: fullname: Perutz – volume: 41 start-page: 13473 year: 2002 end-page: 13482 ident: bb0880 article-title: Protein hydration, thermodynamic binding, and preferential hydration publication-title: Biochemistry contributor: fullname: Timasheff – volume: 322 start-page: 867 year: 2004 end-page: 872 ident: bb0815 article-title: Characterization of the synthetic compatible solute homoectoine as a potent PCR publication-title: Biochem Biophys Res Commun contributor: fullname: Galinski – volume: 76 start-page: 212 year: 2009 end-page: 220 ident: bb0940 article-title: A natural tetrahydropyrimidine protects small bowel from cold ischemia and publication-title: Pathobiology contributor: fullname: van Echten-Deckert – volume: 116 start-page: 313 year: 2004 end-page: 327 ident: bb0005 article-title: Mammalian prion biology: one century of evolving concepts publication-title: Cell contributor: fullname: Polymenidou – volume: 85 start-page: 362 year: 1998 end-page: 368 ident: bb0650 article-title: Accumulation of compatible solutes, ectoine and hydroxyectoine, in a moderate halophile, publication-title: J Ferment Bioeng contributor: fullname: Sakuda – volume: 139 start-page: 129 year: 1993 end-page: 136 ident: bb0070 article-title: Ectoine accumulation and osmotic regulation in publication-title: J Gen Microbiol contributor: fullname: Blanco – volume: 310 start-page: 955 year: 2001 end-page: 963 ident: bb0105 article-title: The osmophobic effect: natural selection of a thermodynamic force in protein folding publication-title: J Mol Biol contributor: fullname: Baskakov – volume: 30 start-page: 1403 year: 2008 end-page: 1407 ident: bb0740 article-title: Cloning and heterologous expression of ectoine biosynthesis genes from publication-title: Biotechnol Lett contributor: fullname: Viswanathan – volume: 469 start-page: 1 year: 1977 end-page: 12 ident: bb0890 article-title: Transient breakdown of permeability barrier of membrane of publication-title: Biochim Biophys Acta contributor: fullname: Kepes – volume: 12 start-page: 391-04 year: 2008 ident: bb0050 article-title: Influence of salts and pH on growth and activity of a novel facultatively alkaliphilic, extremely salt-tolerant, obligately chemolithoautotrophic sufur-oxidizing Gammaproteobacterium publication-title: Extremophiles contributor: fullname: Kuenen – volume: 28 start-page: 479-13 year: 2007 ident: bb0545 article-title: Pathogenesis of chronic obstructive pulmonary disease publication-title: Clin Chest Med contributor: fullname: Macnee – volume: 6 start-page: 15 year: 2002 end-page: 20 ident: bb0090 article-title: Investigation into a stress-inducible promoter region from publication-title: Extremophiles contributor: fullname: Galinski – volume: 111 start-page: 10231 year: 2007 end-page: 10238 ident: bb0965 article-title: Microscopic understanding of preferential exclusion of compatible solute ectoine publication-title: J Phys Chem B contributor: fullname: Nagaoka – volume: 125 start-page: 545 year: 2005 end-page: 553 ident: bb0350 article-title: Ultraviolet A-induced signaling involves a ceramide-mediated autocrine loop leading to ceramide de novo synthesis publication-title: J Invest Dermatol contributor: fullname: Krutmann – volume: 43 start-page: 642 year: 2008 end-page: 646 ident: bb0975 article-title: Promoting effect of compatible solute ectoine on the ethanol fermentation by publication-title: Proc Biochem contributor: fullname: Nagata – volume: 21 start-page: 487 year: 1998 end-page: 497 ident: bb0180 article-title: Characterization of the genes for the biosynthesis of the compatible solute ectoine in the moderately halophilic bacterium publication-title: Syst Appl Microbiol contributor: fullname: Nieto – volume: 170 start-page: 291-06 year: 2006 ident: bb0735 article-title: Engineering for biosynthesis of ectoine (2-methyl 4-carboxy tetrahydro pyrimidine) in tobacco chloroplasts leads to accumulation of ectoine and enhanced salinity tolerance publication-title: Plant Sci contributor: fullname: Sankaranarayanan – volume: 267 start-page: 125 year: 1990 end-page: 132 ident: bb0510 article-title: The human heat-shock protein family. Expression of a novel heat-inducible Hsp70 (Hsp70B′) and isolation of its cDNA and genomic DNA publication-title: Biochem J contributor: fullname: Lim – volume: 66 start-page: 271 year: 1997 end-page: 275 ident: bb0075 article-title: Chronically ultraviolet-exposed human skin shows a higher mutation frequency of mitochondrial DNA as compared to unexposed skin and the hematopoietic system publication-title: Photochem Photobiol contributor: fullname: Ruzicka – volume: 142 start-page: 195-01 year: 1996 ident: bb0810 article-title: Compatible solutes in luminescent bacteria of the genera publication-title: FEMS Microbiol Lett contributor: fullname: Galinski – volume: 136 start-page: 705 year: 1990 end-page: 712 ident: bb0955 article-title: The spectrum of compatible solutes in heterotrophic halophilic eubacteria of the family publication-title: J Gen Microbiol contributor: fullname: Galinski – volume: 4 start-page: 1 year: 2001 end-page: 6 ident: bb0130 article-title: The protective function of compatible solute ectoine on the skin cells and its biomolecules with respect to UV radiation, immunosuppression and membrane damage publication-title: IFSCC Mag contributor: fullname: Driller – volume: 388 start-page: 316 year: 2004 end-page: 321 ident: bb0970 article-title: Slowdown of water diffusion around protein in aqueous solution with ectoine publication-title: Chem Phys Lett contributor: fullname: Nagaoka – volume: 37 start-page: 61 year: 1992 end-page: 65 ident: bb0515 article-title: Enzyme stabilization be ectoine-type compatible solutes: protection against heating, freezing and drying publication-title: Appl Microbiol Biotechnol contributor: fullname: Galinski – volume: 32 start-page: 145 year: 2000 end-page: 153 ident: bb0010 article-title: Stabilizing effect of chemical additives against oxidation of lactate dehydrogenase publication-title: Biotechnol Appl Biochem contributor: fullname: Hatti-Kaul – volume: 362 start-page: 543 year: 1993 end-page: 546 ident: bb0270 article-title: Neurotoxicity of a prion protein fragment publication-title: Nature contributor: fullname: Bugiani – volume: 55 start-page: 1 year: 2006 end-page: 19 ident: bb0730 article-title: Photoaging: mechanisms and repair publication-title: J Am Acad Dermatol contributor: fullname: Sauder – year: 2000 ident: bb0340 article-title: Molekulargenetische und biochemische analyse der biosynthese von 2-methyl-4-carboxy-3,4,5,6-tetrahydropyrimidin und seinem 5-hydroxyderivat, zwei salzstreβinduzierbaren osmolyten in contributor: fullname: Grammel – volume: 91 start-page: 288 year: 2001 end-page: 293 ident: bb0620 article-title: Accumulation of ectoine in the halotolerant publication-title: J Biosci Bioeng contributor: fullname: Wang – volume: 42 start-page: 1311 year: 2001 end-page: 1323 ident: bb0760 article-title: A molecular mechanism for the repression of transcription by the H-NS protein publication-title: Mol Microbiol contributor: fullname: Buc – volume: 9 start-page: 4145 year: 1990 end-page: 4153 ident: bb0230 article-title: Skinner MA.HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure publication-title: EMBO J contributor: fullname: Karn – volume: 4 start-page: 155 year: 2002 end-page: 174 ident: bb0605 article-title: Peptide aggregation in neurodegenerative disease publication-title: Annu Rev Biomed Eng contributor: fullname: Murphy – volume: 280 start-page: 163 year: 1988 end-page: 167 ident: bb0525 article-title: Effects of UVB irradiation on epidermal adenylate cyclase responses publication-title: Arch Dermatol Res contributor: fullname: Ohkuma – volume: 23 start-page: S22 year: 2000 end-page: S26 ident: bb0455 article-title: Ultraviolet A radiation-induced biological effects in human skin: relevance for photoaging and photodermatosis publication-title: J Dermatol Sci contributor: fullname: Krutmann – volume: 94 start-page: 384 year: 2002 end-page: 389 ident: bb0610 article-title: Effect of compatible solutes on the respiratory activity and growth of publication-title: J Biosci Bioeng contributor: fullname: Ishida – volume: 70 start-page: 3130 year: 2004 end-page: 3132 ident: bb0715 article-title: Functional expression of the ectoine hydroxylase gene (thpD) from publication-title: Appl Environ Microbiol contributor: fullname: Bernhardt – year: 2000 ident: bb0085 article-title: Protection of antibodies against proteolytic degradation by compatible solutes contributor: fullname: Kaufmann – volume: 4 start-page: 12 year: 2008 ident: bb0095 article-title: Heterologous ectoine production in publication-title: Saline Systems contributor: fullname: Galinski – volume: 90 start-page: 10962 year: 1993 end-page: 10966 ident: bb0670 article-title: Conversion of alpha-helices into beta-sheets features in the formation of the publication-title: Proc Natl Acad Sci USA contributor: fullname: Groth – volume: 102 start-page: 560 year: 2006 end-page: 563 ident: bb0980 article-title: Supplementation effect of ectoine on thermostability of phytase publication-title: J Biosci Bioeng contributor: fullname: Wang – volume: 153 start-page: 607 year: 1990 end-page: 613 ident: bb0290 article-title: The role of trehalose as a substitute for nitrogen-containing compatible solutes ( publication-title: Arch Microbiol contributor: fullname: Herzog – volume: 74 start-page: 7286 year: 2008 end-page: 7296 ident: bb0155 article-title: Synthesis and uptake of the compatible solutes ectoine and 5-hydroxyectoine by publication-title: Appl Environ Microbiol contributor: fullname: Pierik – volume: 87 start-page: 8985 year: 1990 end-page: 8989 ident: bb0205 article-title: Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 publication-title: Proc Natl Acad Sci USA contributor: fullname: Graham – volume: 3 start-page: 384 year: 2002 end-page: 397 ident: bb0595 article-title: Body shaping under water stress: osmosensing and osmoregulation of solute transport in bacteria publication-title: Chembiochem contributor: fullname: Krämer – volume: 101 start-page: 6433 year: 2004 end-page: 6438 ident: bb0060 article-title: Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution publication-title: Proc Natl Acad Sci USA contributor: fullname: Daggett – volume: 7 start-page: 37 year: 1999 end-page: 45 ident: bb0320 article-title: Protection of a model enzyme (lactate dehydrogenase) against heat, urea and freeze–thaw treatment by compatible solutes additives publication-title: J Mol Catal B Enzym contributor: fullname: Galinski – volume: 6 start-page: 491 year: 2002 end-page: 498 ident: bb0665 article-title: Intracellular ion and organic solute concentrations of the extremely halophilic bacterium publication-title: Extremophiles contributor: fullname: Galinski – volume: 272 start-page: 25794-01 year: 1997 ident: bb0185 article-title: Isolation and characterization of salt-sensitive mutants of the moderate halophile publication-title: J Biol Chem contributor: fullname: Ventosa – volume: 174 start-page: 5027 year: 1992 end-page: 5035 ident: bb0395 article-title: Osmoprotection of publication-title: J Bacteriol contributor: fullname: Blanco – year: 2003 ident: bb0460 article-title: The role of mitochondrial DNA mutations in photoaging of human skin: implications for the development of photoprotective strategies contributor: fullname: Krutmann – volume: 77 start-page: 470 year: 2006 end-page: 477 ident: bb0645 article-title: Intra- and extracellular reactive oxygen species generated by blue light publication-title: J Biomed Mater Res contributor: fullname: Noda – volume: 24 start-page: 263 year: 2000 end-page: 290 ident: bb0945 article-title: Ecological significance of compatible solute accumulation by micro-organisms: from single cells to global climate publication-title: FEMS Microbiol Rev contributor: fullname: Welsh – volume: 29 start-page: 173 year: 2006 end-page: 182 ident: bb0590 article-title: Characterization of salt tolerance in ectoine-transformed tobacco plants ( publication-title: Plant Cell Environ contributor: fullname: Morikawa – volume: 20 start-page: 170 year: 2005 end-page: 178 ident: bb0285 article-title: Ectoine alters subcellular localization of inclusions and reduces apoptotic cell death induced by the truncated Machado–Joseph disease gene product with an expanded polyglutamine stretch publication-title: Neurobiol Dis contributor: fullname: Shoji – volume: 62 start-page: 90 year: 2010 end-page: 95 ident: bb0935 article-title: Ectoine improves yield of biodiesel catalyzed by immobilized lipase publication-title: J Mol Catal Enzym contributor: fullname: Zhang – volume: 84 start-page: 1069 year: 2009 end-page: 1077 ident: bb0355 article-title: A process for the production of ectoine and poly(3-hydroxybutyrate) by publication-title: Appl Microbiol Biotechnol contributor: fullname: Quillaguaman – volume: 14 start-page: 396-02 year: 1998 ident: bb0410 article-title: Protein precipitation: a common etiology in neurodegenerative disorders? publication-title: Trends Genet contributor: fullname: Kakizuka – volume: 176 start-page: 5210 year: 1994 end-page: 5217 ident: bb0865 article-title: Osmoadaptation in rhizobia — ectoine-induced salt tolerance publication-title: J Bacteriol contributor: fullname: Blanco – volume: 63 start-page: 334 year: 1999 end-page: 348 ident: bb0660 article-title: Bioenergetic aspects of halophilism publication-title: Microbiol Mol Biol Rev contributor: fullname: Oren – volume: 4 start-page: 1365 year: 1990 end-page: 1373 ident: bb0780 article-title: A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated publication-title: Genes Dev contributor: fullname: Sonenberg – volume: 61 start-page: 90-04 year: 1997 ident: bb0225 article-title: Evolutionary divergence and salinity-mediated selection in halophilic Archaea publication-title: Microbiol Mol Biol Rev contributor: fullname: Shimmin – volume: 36 start-page: 239 year: 1965 end-page: 246 ident: bb0325 article-title: Senility of the face. Basic study to understand its causes and effects publication-title: Plast Reconstr Surg contributor: fullname: Flores – volume: 43 start-page: 219 year: 1990 end-page: 231 ident: bb0210 article-title: Are freezing and dehydration similar stress vectors? A comparison of modes of interaction of stabilizing solutes with biomolecules publication-title: Cryobiology contributor: fullname: Anchordoguy – year: 1990 ident: bb0125 article-title: Microbial water stress physiology publication-title: Principles and perspectives contributor: fullname: Brown – volume: 65 start-page: 3774 year: 1999 end-page: 3779 ident: bb0175 article-title: Role of N gamma-acetyldiaminobutyrate as an enzyme stabilizer and an intermediate in the biosynthesis of hydroxyectoine publication-title: Appl Environ Microbiol contributor: fullname: Santos – volume: 68 start-page: 93 year: 2002 end-page: 101 ident: bb0360 article-title: Molecular characterization of a thermostable cyanophycin synthetase from the thermophilic cyanobacterium publication-title: Appl Environ Microbiol contributor: fullname: Steinbuchel – volume: 365 start-page: 808 year: 2008 end-page: 813 ident: bb0415 article-title: Small stress molecules inhibit aggregation and neurotoxicity of prion peptide 106–126 publication-title: Biochem Biophys Res Commun contributor: fullname: Park – volume: 73 start-page: 3343 year: 2007 end-page: 3347 ident: bb0825 article-title: Continuous synthesis and excretion of the compatible solute ectoine by a transgenic, nonhalophilic bacterium publication-title: Appl Environ Microbiol contributor: fullname: Breuer – volume: 44 start-page: 837 year: 2001 end-page: 846 ident: bb0930 article-title: Ultraviolet A and melanoma: a review publication-title: J Am Acad Dermatol contributor: fullname: Kopf – volume: 20 start-page: 515 year: 2002 end-page: 521 ident: bb0800 article-title: The production of biocatalysts and biomolecules from extremophiles publication-title: Trends Biotechnol contributor: fullname: De Rosa – volume: 138 start-page: 1629-8 year: 1992 ident: bb0835 article-title: The predominant role of recently discovered tetrahydropyrimidines for the osmoadaptation of halophilic eubacteria publication-title: J Gen Microbiol contributor: fullname: Galinski – year: 2009 ident: bb0905 article-title: Ectoine production by publication-title: Mar Biotechnol (NY) contributor: fullname: Hatti-Kaul – volume: 256 start-page: 7193-01 year: 1981 ident: bb0495 article-title: The stabilization of proteins by sucrose publication-title: J Biol Chem contributor: fullname: Timasheff – volume: 54 start-page: 432 year: 1990 end-page: 449 ident: bb0950 article-title: Role of water in some biological processes publication-title: Microbiol Rev contributor: fullname: Wiggins – volume: 69 start-page: 5919 year: 2003 end-page: 5927 ident: bb0705 article-title: Role of ectoine in publication-title: Appl Environ Microbiol contributor: fullname: Watnick – volume: 7 start-page: 82 year: 2007 ident: bb0575 article-title: Compatible solutes from hyperthermophiles improve the quality of DNA microarrays publication-title: BMC Biotechnol contributor: fullname: Arcelli – volume: 274 start-page: 6920 year: 1999 end-page: 6929 ident: bb0550 article-title: Effect of tetrahydropyrimidine derivatives on protein–nucleic acids interaction publication-title: J Biol Chem contributor: fullname: Lapidot – volume: 22 start-page: 22-2 year: 2006 ident: bb0275 article-title: Protection of skin biological targets by different types of sunscreens publication-title: Photodermatol Photoimmunol Photomed contributor: fullname: Seite – volume: 7 start-page: 22 year: 1999 end-page: 24 ident: bb0140 article-title: Ectoine added protection and care for the skin publication-title: Eur Cosmet contributor: fullname: Bunger – volume: 8 start-page: 133 year: 2004 end-page: 141 ident: bb0585 article-title: Carbon and energy fluxes during haloadaptation of publication-title: Extremophiles contributor: fullname: Kleinsteuber – volume: 26 start-page: 326 year: 2008 end-page: 333 ident: bb0330 article-title: The multifunctional role of ectoine as a natural cell protectant publication-title: Clin Dermatol contributor: fullname: Driller – volume: 187 start-page: 1293-04 year: 2005 ident: bb0390 article-title: Ectoine-induced proteins in publication-title: J Bacteriol contributor: fullname: Blanco – volume: 184 start-page: 3078 year: 2002 end-page: 3085 ident: bb0335 article-title: New type of osmoregulated solute transporter identified in halophilic members of the bacteria domain: TRAP transporter TeaABC mediates uptake of ectoine and hydroxyectoine in publication-title: J Bacteriol contributor: fullname: Kunte – volume: 150 start-page: 3051 year: 2004 end-page: 3063 ident: bb0165 article-title: Complex regulation of the synthesis of the compatible solute ectoine in the halophilic bacterium publication-title: Microbiology contributor: fullname: Ventosa – volume: 78 start-page: 668 year: 2000 end-page: 674 ident: bb0855 article-title: A new phytase expressed in yeast effectively improves the bioavailability of phytate phosphorous to weanling pigs publication-title: J Anim Sci contributor: fullname: Lei – volume: 4 start-page: 253 year: 2006 end-page: 277 ident: bb0425 article-title: Mammalian cell desiccation: facing the challenges publication-title: Cell Preserv Technol contributor: fullname: Acker – volume: 41 start-page: 684 year: 1994 end-page: 688 ident: bb0540 article-title: Survival of publication-title: Appl Microbiol Biotechnol contributor: fullname: Galinski – volume: 19 start-page: 306 year: 1982 end-page: 316 ident: bb0200 article-title: Cellular responses to extreme water loss: the water-replacement hypothesis publication-title: Cryobiology contributor: fullname: Hazlewood – volume: 95 start-page: 9268 year: 1998 end-page: 9273 ident: bb0725 article-title: Osmolyte-driven contraction of a random coil protein publication-title: Proc Natl Acad Sci USA contributor: fullname: Bolen – volume: 100 start-page: 98-07 year: 2006 ident: bb0910 article-title: Ectoines as compatible solutes and carbon and energy sources for the halophilic bacterium publication-title: J Appl Microbiol contributor: fullname: Iglesias-Guerra – volume: 408 start-page: 137 year: 1998 end-page: 146 ident: bb0695 article-title: Oxidative DNA damage induced by visible light in mammalian cells: extent publication-title: Mutat Res contributor: fullname: Epe – volume: 84 start-page: 13 year: 2003 end-page: 20 ident: bb0045 article-title: Potential osmoprotectants for the lactic acid bacteria publication-title: Int J Food Microbiol contributor: fullname: Le Marrec – volume: 64 start-page: 339 year: 1999 end-page: 345 ident: bb0675 article-title: Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join publication-title: Am J Hum Genet contributor: fullname: Paulson – volume: 13 start-page: 717 year: 2009 end-page: 724 ident: bb0985 article-title: Efficient production of ectoine using ectoine-excreting strain publication-title: Extremophiles contributor: fullname: Nagata – volume: 21 start-page: 1206 year: 2005 end-page: 1212 ident: bb0655 article-title: Optimization of ectoine synthesis through fed-batch fermentation of publication-title: Biotechnol Progr contributor: fullname: Vandamme – volume: 3 start-page: 12884 year: 1995 end-page: 12891 ident: bb0520 article-title: The peptide backbone plays a dominant role in protein stabilization by naturally publication-title: Biochemistry contributor: fullname: Bolen – volume: 10 start-page: 716 year: 2008 end-page: 726 ident: bb0795 article-title: Growth phase-dependent switch in osmolyte strategy in a moderate halophile: ectoine is a minor osmolyte but major stationary phase solute in publication-title: Environ Microbiol contributor: fullname: Müller – volume: 117A start-page: 357 year: 1997 end-page: 365 ident: bb0300 article-title: The kosmotropic (structure-forming) effect of compensatory solutes publication-title: Comp Biochem Physiol contributor: fullname: Kinder – volume: 91 start-page: 24 year: 2008 end-page: 34 ident: bb0110 article-title: Genotoxicity of visible light (400–800 nm) and photoprotection assessment of ectoin, publication-title: J Photochem Photobiol contributor: fullname: De Meo – volume: 75 start-page: 2802 year: 2009 end-page: 2810 ident: bb0630 article-title: Osmoadaptation among publication-title: Appl Environ Microbiol contributor: fullname: Boyd – volume: 45 start-page: 6 year: 2007 end-page: 12 ident: bb0170 article-title: Relative importance of amino acids, glycine-betaine and ectoine synthesis in the biocontrol agent publication-title: Lett Appl Microbiol contributor: fullname: Teixido – volume: 29 start-page: 397-07 year: 1998 ident: bb0710 article-title: Regulation of compatible solute accumulation in bacteria publication-title: Mol Microbiol contributor: fullname: Glaasker – volume: 79 start-page: 748 year: 2000 end-page: 763 ident: bb0430 article-title: Nonphytate phosphorus requirement of laying hens with and without phytase on a phase feeding program publication-title: Poult Sci contributor: fullname: Keshavarz – volume: 46 start-page: 28 year: 2006 end-page: 32 ident: bb0375 article-title: Cloning of the ectoine biosynthesis gene ectABC from publication-title: Wei Sheng Wu Xue Bao contributor: fullname: Li – volume: 21 start-page: 531 year: 1997 end-page: 536 ident: bb0635 article-title: publication-title: Enzyme Microb Technol contributor: fullname: Iborra – volume: 283 start-page: 7309 year: 2008 end-page: 7313 ident: bb0150 article-title: Intracellular organic osmolytes: function and regulation publication-title: J Biol Chem contributor: fullname: Ferraris – volume: 8 start-page: 101 year: 1986 end-page: 104 ident: bb0750 article-title: Osmotic shock induced release of low molecular weight metabolites from free living and immobilized cyanobacteria publication-title: Enzyme Microb Technol contributor: fullname: Stewart – volume: 70 start-page: 3143 year: 2004 end-page: 3145 ident: bb0570 article-title: Plastic encapsulation of stabilized publication-title: Appl Environ Microbiol contributor: fullname: Tunnacliffe – volume: 4 start-page: 6 year: 2008 ident: bb0475 article-title: Compatible solute influence on nucleic acids: many questions but few answers publication-title: Saline Sys contributor: fullname: Kurz – start-page: 77 year: 2000 end-page: 97 ident: bb0115 article-title: Coping with osmotic challenges: osmoregulation through accumulation and release of compatible solutes in bacteria publication-title: Bacterial stress responses contributor: fullname: Krämer – volume: 59 start-page: 39-5 year: 1998 ident: bb0830 article-title: Chemical synthesis of polyaspartates: a biodegradable alternative to currently used polycarboxylate homo- and copolymers publication-title: Polym Degrad Stab contributor: fullname: Schwamborn – volume: 113 start-page: 113 year: 1993 end-page: 118 ident: bb0260 article-title: Fate of compatible solutes during dilution stress in publication-title: FEMS Microbiol Lett contributor: fullname: Oren – volume: 214 start-page: 101 year: 2003 end-page: 111 ident: bb0190 article-title: Membrane cell retention systems for continuous production of publication-title: J Membr Sci contributor: fullname: Iborra – volume: 10 start-page: 197-03 year: 2005 ident: bb0145 article-title: Ectoine from halophilic microorganisms induces the expression of hsp70 and hsp70B′ in human keratinocytes modulating the proinflammatory response publication-title: Cell Stress Chaperones contributor: fullname: De Rosa – volume: 68 start-page: 772 year: 2002 end-page: 783 ident: bb0465 article-title: Osmotically regulated synthesis of the compatible solute ectoine in publication-title: Appl Environ Microbiol contributor: fullname: Bremer – volume: 1528 start-page: 60 year: 2001 end-page: 70 ident: bb0580 article-title: Calorimetrically obtained information about the efficiency of ectoine synthesis from glucose in publication-title: Biochim Biophys Acta contributor: fullname: Babel – volume: 23 start-page: 345 year: 2005 end-page: 357 ident: bb0840 article-title: Growing publication-title: Biotechnol Adv contributor: fullname: Fass – volume: 21 start-page: 208 year: 2005 end-page: 211 ident: bb0990 article-title: Bacterial translocation in acute rejection after small bowel transplantation in rats publication-title: Pediatr Surg Int contributor: fullname: Fernandez-Dumont – volume: 178 start-page: 385 year: 1996 end-page: 395 ident: bb0555 article-title: Induction of synthesis of tetrahydropyrimidine derivatives in publication-title: J Bacteriol contributor: fullname: Lapidot – volume: 6 start-page: 31 year: 2007 ident: bb0065 article-title: Production of publication-title: Microb Cell Fact contributor: fullname: Iborra – volume: 66 start-page: 385-07 year: 1997 ident: bb0370 article-title: Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins publication-title: Annu Rev Biochem contributor: fullname: Lansbury – volume: 48 start-page: 519 year: 2003 end-page: 529 ident: bb0315 article-title: A possible cardioprotective effect of heat shock proteins during cardiac surgery in pediatric patients publication-title: Pharmacol Res contributor: fullname: Del Ry – volume: 107 start-page: 124 year: 2010 end-page: 133 ident: bb0245 article-title: Process optimization of the integrated synthesis and secretion of ectoine and hydroxyectoine under hyper/hypo osmotic stress publication-title: Biotechnol Bioeng contributor: fullname: Franco-Lara – volume: 60 start-page: 350 year: 2004 end-page: 352 ident: bb0365 article-title: Expression, purification and crystallization of human 3′-phosphoadenosine-5′-phosphosulfate synthetase 1 publication-title: Acta Crystallogr D contributor: fullname: Bayer – volume: 18 start-page: 443 year: 1988 end-page: 458 ident: bb0895 article-title: Production, rapid purification and catalytic characterization of extracellular publication-title: Prep Biochem contributor: fullname: Ullah – volume: 5 start-page: D796 year: 2000 end-page: D812 ident: bb0765 article-title: Osmoadaptation and osmoregulation in archaea publication-title: Front Biosci contributor: fullname: Roberts – volume: 38 start-page: 272 year: 1974 end-page: 290 ident: bb0480 article-title: Salt dependent properties of proteins from extremely halophilic bacteria publication-title: Bacteriol Rev contributor: fullname: Lanyi – volume: 43 start-page: 326 year: 2004 end-page: 335 ident: bb0785 article-title: Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis publication-title: Int J Dermatol contributor: fullname: Thiele – volume: 69 start-page: 121 year: 1969 end-page: 126 ident: bb0745 article-title: publication-title: Arch Mikrobiol contributor: fullname: Sistrom – volume: 1 start-page: 5 year: 2005 ident: bb0770 article-title: Organic compatible solutes of halotolerant and halophilic microorganisms publication-title: Saline Systems contributor: fullname: Roberts – volume: 147 start-page: 46 year: 2010 end-page: 51 ident: bb0900 article-title: High productivity of ectoines by publication-title: J Biotechnol contributor: fullname: Hatti-Kaul – volume: 367 start-page: 33 year: 1995 end-page: 38 ident: bb0485 article-title: Tetrahydropyrimidine derivatives inhibit binding of a Tat-like, arginine-containing peptide, to HIV TAR RNA publication-title: FEBS Lett contributor: fullname: Eisenstein – volume: 36 start-page: 9101 year: 1997 end-page: 9108 ident: bb0925 article-title: A naturally occurring protective system in urea-rich cells: mechanism of osmolyte publication-title: Biochemistry contributor: fullname: Bolen – volume: 46 start-page: 152 year: 1983 end-page: 159 ident: bb0505 article-title: Glycine betaine, an osmotic effector in publication-title: Appl Environ Microbiol contributor: fullname: Bouillard – volume: 174 start-page: 1586 year: 1992 end-page: 1595 ident: bb0195 article-title: Origins of the osmoprotective properties of betaine and proline in publication-title: J Bacteriol contributor: fullname: Record – volume: 208 start-page: 2819 year: 2005 end-page: 2830 ident: bb0960 article-title: Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses publication-title: J Exp Biol contributor: fullname: Yancey – volume: 22 start-page: 568 year: 2006 end-page: 576 ident: bb0215 article-title: Screening of novel excipients for improving the stability of retroviral and adenoviral vectors publication-title: Biotechnol Prog contributor: fullname: Alves – volume: 43 start-page: 53-1 year: 1995 ident: bb0280 article-title: Production of hydroxyectoine-high cell-density cultivation and osmotic downshock of publication-title: J Biotechnol contributor: fullname: Galinski – volume: 274 start-page: 15345 year: 1999 end-page: 15349 ident: bb0080 article-title: Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion publication-title: J Biol Chem contributor: fullname: Sies – volume: 144 start-page: 260 year: 2001 end-page: 266 ident: bb0850 article-title: Treatment with 815-nm diode laser induces long-lasting expression of 72-kDa heat publication-title: Br J Dermatol contributor: fullname: Bachelet – volume: 15 start-page: 1019 year: 1981 end-page: 1023 ident: bb0845 article-title: A spectrum response study on single strand DNA breaks, sister chromatid publication-title: Pediatr Res contributor: fullname: Vitsa – volume: 47 start-page: 411 year: 1985 end-page: 414 ident: bb0020 article-title: The stabilization of proteins by osmolytes publication-title: Biophys J contributor: fullname: Timasheff – volume: 99 start-page: 941 year: 2008 end-page: 948 ident: bb0615 article-title: Efficient cyclic system to yield ectoine using publication-title: Biotechnol Bioeng contributor: fullname: Sasaki – volume: 263 start-page: 16014 year: 1988 end-page: 16022 ident: bb0385 article-title: The structure and biosynthesis of new tetrahydropyrimidine derivatives in actinomycin-D producer publication-title: J Biol Chem contributor: fullname: Lapidot – volume: 73 start-page: 594-51 year: 2009 ident: bb0530 article-title: Cohesion group approach for evolutionary analysis of aspartokinase, an enzyme that feeds a branched network of many biochemical pathways publication-title: Microbiol Mol Biol Rev contributor: fullname: Jensen – volume: 76 start-page: 3575 year: 2010 end-page: 3589 ident: bb0025 article-title: Interplay between iron homeostasis and the osmotic stress response in the halophilic bacterium publication-title: Appl Environ Microbiol contributor: fullname: Vargas – volume: 233 start-page: 347 year: 2004 end-page: 352 ident: bb0565 article-title: High survival and stability rates of publication-title: FEMS Microbiol Lett contributor: fullname: Tunnacliffe – volume: 51 start-page: 422 year: 1999 end-page: 430 ident: bb0755 article-title: High-cell-density cultivation of microorganisms publication-title: Appl Microbiol Biotechnol contributor: fullname: Guthke – volume: 17 start-page: 232 year: 2004 end-page: 237 ident: bb0135 article-title: Ectoin: an effective natural substance to prevent UVA-induced premature photoaging publication-title: Skin Pharmacol Physiol contributor: fullname: Driller – volume: 2 start-page: 154 year: 2003 end-page: 160 ident: bb0235 article-title: Protein folding and disease: a view from the first Horizon Symposium publication-title: Nat Rev Drug Discov contributor: fullname: Dobson – volume: 366 start-page: 900 year: 2007 end-page: 915 ident: bb0720 article-title: The role of LRP and H-NS in transcription regulation: involvement of synergism publication-title: J Mol Biol contributor: fullname: Wagner – volume: 1 start-page: 23 year: 1996 end-page: 28 ident: bb0870 article-title: A hitchhiker's guide to the human Hsp70 family publication-title: Cell Stress Chaperones contributor: fullname: Anderson – volume: 66 start-page: 1572 year: 2000 end-page: 1579 ident: bb0055 article-title: Compatible-solute-supported periplasmic expression of functional recombinant proteins under stress conditions publication-title: Appl Environ Microbiol contributor: fullname: Engert – volume: 22 start-page: 169 year: 1996 end-page: 172 ident: bb0250 article-title: Ectoine as the predominant osmolyte in the marine bacterium publication-title: Lett Appl Microbiol contributor: fullname: Gauthier – volume: 122 start-page: 1239 year: 2000 end-page: 1247 ident: bb0625 article-title: Ectoine, the compatible solute of publication-title: Plant Physiol contributor: fullname: Shinmyo – volume: 351 start-page: 1721 year: 2004 end-page: 1730 ident: bb0685 article-title: Exposure to traffic and the onset of myocardial infarction publication-title: N Engl J Med contributor: fullname: Wichmann – volume: 26 start-page: 9 year: 2000 end-page: 12 ident: bb0255 article-title: Polyglutamine expansions: proteolysis, chaperones, and the dangers of promiscuity publication-title: Neuron contributor: fullname: Silver – volume: 1764 start-page: 1234 year: 2006 end-page: 1242 ident: bb0445 article-title: Compatible solutes as protectants for zymogens against proteolysis publication-title: Biochim Biophys Acta contributor: fullname: Gutschow – volume: 10 start-page: 287-01 year: 2008 ident: bb0120 article-title: The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis publication-title: Antioxid Redox Signal contributor: fullname: Marsh – volume: 188 start-page: 3774 year: 2006 end-page: 3784 ident: bb0310 article-title: The ectD gene, which is involved in the synthesis of the compatible solute hydroxyectoine, is essential for thermoprotection of the halophilic bacterium publication-title: J Bacteriol contributor: fullname: Nieto – volume: 57 start-page: 306 year: 1998 end-page: 313 ident: bb0790 article-title: Bacterial milking: a novel bioprocess for production of compatible solutes publication-title: Biotechnol Bioeng contributor: fullname: Galinski – volume: 564 start-page: 121 year: 2004 end-page: 125 ident: bb0030 article-title: Inhibition of insulin amyloid formation by small stress molecules publication-title: FEBS Lett contributor: fullname: Park – volume: 20 start-page: 211 year: 2007 end-page: 218 ident: bb0380 article-title: publication-title: Skin Pharmacol Physiol contributor: fullname: Tronnier – volume: 149 start-page: 135 year: 1985 end-page: 139 ident: bb0295 article-title: 1, 4, 5, 6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid — a novel cyclic amino-acid from halophilic phototrophic bacteria of the genus publication-title: Eur J Biochem contributor: fullname: Trüper – volume: 62 start-page: 504 year: 1998 end-page: 544 ident: bb0915 article-title: Biology of moderately halophilic aerobic bacteria publication-title: Microbiol Mol Biol Rev contributor: fullname: Oren – volume: 579 start-page: 4775 year: 2005 end-page: 4780 ident: bb0420 article-title: Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer's beta-amyloid publication-title: FEBS Lett contributor: fullname: Park – volume: 61 start-page: 117 year: 1998 end-page: 153 ident: bb0220 article-title: An overview of the role and diversity of compatible solutes in Bacteria and Archaea publication-title: Adv Biochem Eng Biotechnol contributor: fullname: Antranikian – volume: 71 start-page: 157 year: 1990 end-page: 162 ident: bb0690 article-title: The biosynthesis of ectoine publication-title: FEMS Microbiol Lett contributor: fullname: Trüper – volume: 180 start-page: 29 year: 2009 end-page: 35 ident: bb0860 article-title: The compatible solute ectoine protects against nanoparticle-induced neutrophilic publication-title: Am J Respir Crit Care Med contributor: fullname: Unfried – volume: 335 start-page: 181 year: 1990 end-page: 184 ident: bb0345 article-title: Successful small-bowel/liver transplantation publication-title: Lancet contributor: fullname: Garcia – volume: 3 start-page: 191 year: 1999 end-page: 198 ident: bb0435 article-title: Extrinsic protein stabilization by the naturally occurring osmolytes beta-hydroxyectoine and betaine publication-title: Extremophiles contributor: fullname: Galinski – volume: 3 start-page: 743 year: 2001 end-page: 754 ident: bb0775 article-title: Osmoadaptation in Bacteria and Archaea: common principles and differences publication-title: Environ Microbiol contributor: fullname: Müller – volume: 211 start-page: 213 year: 2002 end-page: 218 ident: bb0875 article-title: The substrate-binding protein TeaA of the osmoregulated ectoine transporter TeaABC from publication-title: FEMS Microbiol Lett contributor: fullname: Kunte – volume: 126 start-page: 26 year: 2000 end-page: 29 ident: bb0100 article-title: Ectoine, an innovative, multifunctional, active substance for the cosmetic industry publication-title: SOWF J contributor: fullname: Bunger – volume: 143 start-page: 1141 year: 1997 end-page: 1149 ident: bb0535 article-title: Characterization of genes for the biosynthesis of the compatible solute ectoine from publication-title: Microbiology contributor: fullname: Galinski – volume: 23 start-page: 40 year: 2005 end-page: 41 ident: bb0400 article-title: Ethanol fermentation on the move publication-title: Nat Biotechnol contributor: fullname: Jeffries – volume: 383 start-page: 945 year: 2002 end-page: 960 ident: bb0820 article-title: The bacterial regulatory protein H-NS — a versatile modulator of nucleic acid publication-title: Biol Chem contributor: fullname: Wagner – volume: 157 start-page: 693 year: 2006 end-page: 699 ident: bb0805 article-title: High-yield cultivation of publication-title: Res Microbiol contributor: fullname: De Rosa – volume: 8 start-page: 175 year: 2004 end-page: 184 ident: bb0920 article-title: publication-title: Extremophiles contributor: fullname: Kunte – volume: 68 start-page: 554 year: 1998 end-page: 561 ident: bb0450 article-title: Ischaemia–reperfusion injury to the intestine publication-title: Aust N Z J Surg contributor: fullname: Hall – volume: 77 start-page: 2777 year: 1980 end-page: 2781 ident: bb0885 article-title: Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species publication-title: Proc Natl Acad Sci USA contributor: fullname: Cutler – volume: 72 start-page: 623 year: 2006 end-page: 634 ident: bb0500 article-title: Extremolytes: natural compounds from extremophiles for versatile applications publication-title: Appl Microbiol Biotechnol contributor: fullname: Schwarz – volume: 282 start-page: 31147 year: 2007 end-page: 31155 ident: bb0160 article-title: Osmotically induced synthesis of the compatible solute hydroxyectoine is mediated by an evolutionarily conserved ectoine hydroxylase publication-title: J Biol Chem contributor: fullname: Bremer – volume: 3 start-page: 94 year: 2006 end-page: 99 ident: bb0470 article-title: Osmoregulation in Bacteria: compatible solute accumulation and osmosensing publication-title: Environ Chem contributor: fullname: Kunte – volume: 131 start-page: 20 year: 2005 end-page: 30 ident: bb0700 article-title: Complete photo protection — going beyond visible endpoints publication-title: SOWF J contributor: fullname: Lergenmuller – volume: 274 start-page: 196-3 year: 2007 ident: bb0035 article-title: Response of publication-title: FEMS Microbiol Lett contributor: fullname: Peyton – volume: 51 start-page: 1457 year: 2001 end-page: 1462 ident: bb0015 article-title: publication-title: Int J Syst Evol Microbiol contributor: fullname: Ventosa – volume: 76 start-page: 3575 year: 2010 ident: 10.1016/j.biotechadv.2010.06.005_bb0025 article-title: Interplay between iron homeostasis and the osmotic stress response in the halophilic bacterium Chromohalobacter salexigens publication-title: Appl Environ Microbiol doi: 10.1128/AEM.03136-09 contributor: fullname: Argandoña – volume: 32 start-page: 145 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0010 article-title: Stabilizing effect of chemical additives against oxidation of lactate dehydrogenase publication-title: Biotechnol Appl Biochem doi: 10.1042/BA20000014 contributor: fullname: Andersson – volume: 85 start-page: 362 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0650 article-title: Accumulation of compatible solutes, ectoine and hydroxyectoine, in a moderate halophile, Halomonas elongata KS3 isolated from dry salty land in Thailand publication-title: J Ferment Bioeng doi: 10.1016/S0922-338X(98)80078-0 contributor: fullname: Ono – volume: 274 start-page: 196-3 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0035 article-title: Response of Halomonas campisalis to saline stress: changes in growth kinetics, compatible solute production and membrane phospholipid fatty acid composition publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.2007.00851.x contributor: fullname: Aston – volume: 51 start-page: 1457 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0015 article-title: Chromohalobacter salexigens sp. nov., a moderately halophilic species that includes Halomonas elongata DSM 3043 and ATCC 33174 publication-title: Int J Syst Evol Microbiol doi: 10.1099/00207713-51-4-1457 contributor: fullname: Arahal – volume: 1528 start-page: 60 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0580 article-title: Calorimetrically obtained information about the efficiency of ectoine synthesis from glucose in Halomonas elongata publication-title: Biochim Biophys Acta doi: 10.1016/S0304-4165(01)00172-6 contributor: fullname: Maskow – volume: 59 start-page: 39-5 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0830 article-title: Chemical synthesis of polyaspartates: a biodegradable alternative to currently used polycarboxylate homo- and copolymers publication-title: Polym Degrad Stab doi: 10.1016/S0141-3910(97)00184-5 contributor: fullname: Schwamborn – volume: 13 start-page: 717 year: 2009 ident: 10.1016/j.biotechadv.2010.06.005_bb0985 article-title: Efficient production of ectoine using ectoine-excreting strain publication-title: Extremophiles doi: 10.1007/s00792-009-0262-2 contributor: fullname: Zhang – volume: 263 start-page: 16014 year: 1988 ident: 10.1016/j.biotechadv.2010.06.005_bb0385 article-title: The structure and biosynthesis of new tetrahydropyrimidine derivatives in actinomycin-D producer Streptomyces parvulus. Use of C-13-labeled and N-15-labeled glutamate and C-13 and N-15 NMR-spectroscopy publication-title: J Biol Chem doi: 10.1016/S0021-9258(18)37550-1 contributor: fullname: Inbar – volume: 42 start-page: 1311 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0760 article-title: A molecular mechanism for the repression of transcription by the H-NS protein publication-title: Mol Microbiol doi: 10.1046/j.1365-2958.2001.02706.x contributor: fullname: Rimsky – volume: 188 start-page: 3774 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0310 article-title: The ectD gene, which is involved in the synthesis of the compatible solute hydroxyectoine, is essential for thermoprotection of the halophilic bacterium Chromohalobacter salexigens publication-title: J Bacteriol doi: 10.1128/JB.00136-06 contributor: fullname: Garcia-Estepa – volume: 22 start-page: 568 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0215 article-title: Screening of novel excipients for improving the stability of retroviral and adenoviral vectors publication-title: Biotechnol Prog doi: 10.1021/bp050294y contributor: fullname: Cruz – volume: 174 start-page: 1586 year: 1992 ident: 10.1016/j.biotechadv.2010.06.005_bb0195 article-title: Origins of the osmoprotective properties of betaine and proline in Escherichia coli K-12 publication-title: J Bacteriol doi: 10.1128/jb.174.5.1586-1595.1992 contributor: fullname: Cayley – volume: 3 start-page: 191 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0435 article-title: Extrinsic protein stabilization by the naturally occurring osmolytes beta-hydroxyectoine and betaine publication-title: Extremophiles doi: 10.1007/s007920050116 contributor: fullname: Knapp – volume: 24 start-page: 263 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0945 article-title: Ecological significance of compatible solute accumulation by micro-organisms: from single cells to global climate publication-title: FEMS Microbiol Rev doi: 10.1111/j.1574-6976.2000.tb00542.x contributor: fullname: Welsh – volume: 43 start-page: 642 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0975 article-title: Promoting effect of compatible solute ectoine on the ethanol fermentation by Zymomonas mobilis CICC10232 publication-title: Proc Biochem doi: 10.1016/j.procbio.2008.02.003 contributor: fullname: Zhang – volume: 66 start-page: 271 year: 1997 ident: 10.1016/j.biotechadv.2010.06.005_bb0075 article-title: Chronically ultraviolet-exposed human skin shows a higher mutation frequency of mitochondrial DNA as compared to unexposed skin and the hematopoietic system publication-title: Photochem Photobiol doi: 10.1111/j.1751-1097.1997.tb08654.x contributor: fullname: Berneburg – volume: 282 start-page: 31147 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0160 article-title: Osmotically induced synthesis of the compatible solute hydroxyectoine is mediated by an evolutionarily conserved ectoine hydroxylase publication-title: J Biol Chem doi: 10.1074/jbc.M704023200 contributor: fullname: Bursy – volume: 20 start-page: 211 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0380 article-title: In vivo assessment of ectoin: a randomized, vehicle-controlled clinical trial publication-title: Skin Pharmacol Physiol doi: 10.1159/000103204 contributor: fullname: Heinrich – volume: 7 start-page: 37 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0320 article-title: Protection of a model enzyme (lactate dehydrogenase) against heat, urea and freeze–thaw treatment by compatible solutes additives publication-title: J Mol Catal B Enzym doi: 10.1016/S1381-1177(99)00043-0 contributor: fullname: Göller – volume: 60 start-page: 350 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0365 article-title: Expression, purification and crystallization of human 3′-phosphoadenosine-5′-phosphosulfate synthetase 1 publication-title: Acta Crystallogr D doi: 10.1107/S0907444903027628 contributor: fullname: Harjes – volume: 8 start-page: 133 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0585 article-title: Carbon and energy fluxes during haloadaptation of Halomonas sp. EF11 growing on phenol publication-title: Extremophiles doi: 10.1007/s00792-003-0372-1 contributor: fullname: Maskow – volume: 47 start-page: 411 year: 1985 ident: 10.1016/j.biotechadv.2010.06.005_bb0020 article-title: The stabilization of proteins by osmolytes publication-title: Biophys J doi: 10.1016/S0006-3495(85)83932-1 contributor: fullname: Arakawa – volume: 131 start-page: 20 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0700 article-title: Complete photo protection — going beyond visible endpoints publication-title: SOWF J contributor: fullname: Pfluecker – volume: 1 start-page: 23 year: 1996 ident: 10.1016/j.biotechadv.2010.06.005_bb0870 article-title: A hitchhiker's guide to the human Hsp70 family publication-title: Cell Stress Chaperones doi: 10.1379/1466-1268(1996)001<0023:AHSGTT>2.3.CO;2 contributor: fullname: Tavaria – year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0125 article-title: Microbial water stress physiology contributor: fullname: Brown – volume: 4 start-page: 155 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0605 article-title: Peptide aggregation in neurodegenerative disease publication-title: Annu Rev Biomed Eng doi: 10.1146/annurev.bioeng.4.092801.094202 contributor: fullname: Murphy – volume: 2 start-page: 154 year: 2003 ident: 10.1016/j.biotechadv.2010.06.005_bb0235 article-title: Protein folding and disease: a view from the first Horizon Symposium publication-title: Nat Rev Drug Discov doi: 10.1038/nrd1013 contributor: fullname: Dobson – volume: 4 start-page: 12 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0095 article-title: Heterologous ectoine production in Escherichia coli: by-passing the metabolic bottle-neck publication-title: Saline Systems doi: 10.1186/1746-1448-4-12 contributor: fullname: Bestvater – volume: 3 start-page: 12884 issue: 4 year: 1995 ident: 10.1016/j.biotechadv.2010.06.005_bb0520 article-title: The peptide backbone plays a dominant role in protein stabilization by naturally publication-title: Biochemistry doi: 10.1021/bi00039a051 contributor: fullname: Liu – volume: 176 start-page: 5210 year: 1994 ident: 10.1016/j.biotechadv.2010.06.005_bb0865 article-title: Osmoadaptation in rhizobia — ectoine-induced salt tolerance publication-title: J Bacteriol doi: 10.1128/jb.176.17.5210-5217.1994 contributor: fullname: Talibart – volume: 76 start-page: 212 year: 2009 ident: 10.1016/j.biotechadv.2010.06.005_bb0940 article-title: A natural tetrahydropyrimidine protects small bowel from cold ischemia and publication-title: Pathobiology doi: 10.1159/000218338 contributor: fullname: Wei – volume: 48 start-page: 519 year: 2003 ident: 10.1016/j.biotechadv.2010.06.005_bb0315 article-title: A possible cardioprotective effect of heat shock proteins during cardiac surgery in pediatric patients publication-title: Pharmacol Res doi: 10.1016/S1043-6618(03)00193-2 contributor: fullname: Giannessi – start-page: 77 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0115 article-title: Coping with osmotic challenges: osmoregulation through accumulation and release of compatible solutes in bacteria contributor: fullname: Bremer – volume: 20 start-page: 515 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0800 article-title: The production of biocatalysts and biomolecules from extremophiles publication-title: Trends Biotechnol doi: 10.1016/S0167-7799(02)02073-5 contributor: fullname: Schiraldi – volume: 138 start-page: 1629-8 year: 1992 ident: 10.1016/j.biotechadv.2010.06.005_bb0835 article-title: The predominant role of recently discovered tetrahydropyrimidines for the osmoadaptation of halophilic eubacteria publication-title: J Gen Microbiol doi: 10.1099/00221287-138-11-2473 contributor: fullname: Severin – volume: 22 start-page: 169 year: 1996 ident: 10.1016/j.biotechadv.2010.06.005_bb0250 article-title: Ectoine as the predominant osmolyte in the marine bacterium Marinobacter hydrocarbonoclasticus grown on eicosane at high salinities publication-title: Lett Appl Microbiol doi: 10.1111/j.1472-765X.1996.tb01135.x contributor: fullname: Fernandez-Linares – volume: 77 start-page: 470 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0645 article-title: Intra- and extracellular reactive oxygen species generated by blue light publication-title: J Biomed Mater Res doi: 10.1002/jbm.a.30663 contributor: fullname: Omata – volume: 6 start-page: 31 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0065 article-title: Production of l-carnitine by secondary metabolism of bacteria publication-title: Microb Cell Fact doi: 10.1186/1475-2859-6-31 contributor: fullname: Bernal – volume: 351 start-page: 1721 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0685 article-title: Exposure to traffic and the onset of myocardial infarction publication-title: N Engl J Med doi: 10.1056/NEJMoa040203 contributor: fullname: Peters – volume: 75 start-page: 2802 year: 2009 ident: 10.1016/j.biotechadv.2010.06.005_bb0630 article-title: Osmoadaptation among Vibrio species and unique genomic features and physiological publication-title: Appl Environ Microbiol doi: 10.1128/AEM.01698-08 contributor: fullname: Naughton – volume: 174 start-page: 5027 year: 1992 ident: 10.1016/j.biotechadv.2010.06.005_bb0395 article-title: Osmoprotection of Escherichia coli by ectoine — uptake and accumulation characteristics publication-title: J Bacteriol doi: 10.1128/jb.174.15.5027-5035.1992 contributor: fullname: Jebbar – volume: 113 start-page: 113 year: 1993 ident: 10.1016/j.biotechadv.2010.06.005_bb0260 article-title: Fate of compatible solutes during dilution stress in Ectothiorhodospira marismortui publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.1993.tb06497.x contributor: fullname: Fischel – volume: 26 start-page: 326 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0330 article-title: The multifunctional role of ectoine as a natural cell protectant publication-title: Clin Dermatol doi: 10.1016/j.clindermatol.2008.01.002 contributor: fullname: Graf – volume: 84 start-page: 1069 year: 2009 ident: 10.1016/j.biotechadv.2010.06.005_bb0355 article-title: A process for the production of ectoine and poly(3-hydroxybutyrate) by Halomonas boliviensis publication-title: Appl Microbiol Biotechnol doi: 10.1007/s00253-009-2036-2 contributor: fullname: Guzman – volume: 274 start-page: 6920 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0550 article-title: Effect of tetrahydropyrimidine derivatives on protein–nucleic acids interaction publication-title: J Biol Chem doi: 10.1074/jbc.274.11.6920 contributor: fullname: Malin – volume: 65 start-page: 3774 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0175 article-title: Role of N gamma-acetyldiaminobutyrate as an enzyme stabilizer and an intermediate in the biosynthesis of hydroxyectoine publication-title: Appl Environ Microbiol doi: 10.1128/AEM.65.9.3774-3779.1999 contributor: fullname: Canovas – volume: 26 start-page: 9 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0255 article-title: Polyglutamine expansions: proteolysis, chaperones, and the dangers of promiscuity publication-title: Neuron doi: 10.1016/S0896-6273(00)81132-0 contributor: fullname: Ferrigno – volume: 187 start-page: 1293-04 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0390 article-title: Ectoine-induced proteins in Sinorhizobium meliloti include an ectoine ABC-type transporter involved in osmoprotection and ectoine catabolism publication-title: J Bacteriol doi: 10.1128/JB.187.4.1293-1304.2005 contributor: fullname: Jebbar – volume: 3 start-page: 94 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0470 article-title: Osmoregulation in Bacteria: compatible solute accumulation and osmosensing publication-title: Environ Chem doi: 10.1071/EN06016 contributor: fullname: Kunte – volume: 149 start-page: 135 year: 1985 ident: 10.1016/j.biotechadv.2010.06.005_bb0295 article-title: 1, 4, 5, 6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid — a novel cyclic amino-acid from halophilic phototrophic bacteria of the genus Ectothiorhodospira publication-title: Eur J Biochem doi: 10.1111/j.1432-1033.1985.tb08903.x contributor: fullname: Galinski – volume: 469 start-page: 1 year: 1977 ident: 10.1016/j.biotechadv.2010.06.005_bb0890 article-title: Transient breakdown of permeability barrier of membrane of Escherichia coli upon hypoosmotic shock publication-title: Biochim Biophys Acta doi: 10.1016/0005-2736(77)90320-0 contributor: fullname: Tsapis – volume: 68 start-page: 772 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0465 article-title: Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp. publication-title: Appl Environ Microbiol doi: 10.1128/AEM.68.2.772-783.2002 contributor: fullname: Kuhlmann – volume: 74 start-page: 7286 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0155 article-title: Synthesis and uptake of the compatible solutes ectoine and 5-hydroxyectoine by Streptomyces coelicolor A3(2) in response to salt and heat stresses publication-title: Appl Environ Microbiol doi: 10.1128/AEM.00768-08 contributor: fullname: Bursy – volume: 46 start-page: 152 year: 1983 ident: 10.1016/j.biotechadv.2010.06.005_bb0505 article-title: Glycine betaine, an osmotic effector in Klebsiella pneumoniae and other members of the Enterobacteriaceae publication-title: Appl Environ Microbiol doi: 10.1128/AEM.46.1.152-159.1983 contributor: fullname: Le Rudulier – volume: 73 start-page: 3343 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0825 article-title: Continuous synthesis and excretion of the compatible solute ectoine by a transgenic, nonhalophilic bacterium publication-title: Appl Environ Microbiol doi: 10.1128/AEM.02482-06 contributor: fullname: Schubert – volume: 14 start-page: 396-02 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0410 article-title: Protein precipitation: a common etiology in neurodegenerative disorders? publication-title: Trends Genet doi: 10.1016/S0168-9525(98)01559-5 contributor: fullname: Kakizuka – volume: 61 start-page: 90-04 year: 1997 ident: 10.1016/j.biotechadv.2010.06.005_bb0225 article-title: Evolutionary divergence and salinity-mediated selection in halophilic Archaea publication-title: Microbiol Mol Biol Rev doi: 10.1128/.61.1.90-104.1997 contributor: fullname: Dennis – volume: 256 start-page: 7193-01 year: 1981 ident: 10.1016/j.biotechadv.2010.06.005_bb0495 article-title: The stabilization of proteins by sucrose publication-title: J Biol Chem doi: 10.1016/S0021-9258(19)68947-7 contributor: fullname: Lee – volume: 63 start-page: 334 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0660 article-title: Bioenergetic aspects of halophilism publication-title: Microbiol Mol Biol Rev doi: 10.1128/MMBR.63.2.334-348.1999 contributor: fullname: Oren – volume: 126 start-page: 26 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0100 article-title: Ectoine, an innovative, multifunctional, active substance for the cosmetic industry publication-title: SOWF J contributor: fullname: Beyer – volume: 139 start-page: 129 year: 1993 ident: 10.1016/j.biotechadv.2010.06.005_bb0070 article-title: Ectoine accumulation and osmotic regulation in Brevibacterium linens publication-title: J Gen Microbiol doi: 10.1099/00221287-139-1-129 contributor: fullname: Bernard – volume: 322 start-page: 867 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0815 article-title: Characterization of the synthetic compatible solute homoectoine as a potent PCR publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2004.07.200 contributor: fullname: Schnoor – volume: 136 start-page: 705 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0955 article-title: The spectrum of compatible solutes in heterotrophic halophilic eubacteria of the family Halomonadaceae publication-title: J Gen Microbiol doi: 10.1099/00221287-136-4-705 contributor: fullname: Wohlfarth – volume: 79 start-page: 748 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0430 article-title: Nonphytate phosphorus requirement of laying hens with and without phytase on a phase feeding program publication-title: Poult Sci doi: 10.1093/ps/79.5.748 contributor: fullname: Keshavarz – ident: 10.1016/j.biotechadv.2010.06.005_bb0490 – volume: 17 start-page: 232 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0135 article-title: Ectoin: an effective natural substance to prevent UVA-induced premature photoaging publication-title: Skin Pharmacol Physiol doi: 10.1159/000080216 contributor: fullname: Buenger – volume: 367 start-page: 33 year: 1995 ident: 10.1016/j.biotechadv.2010.06.005_bb0485 article-title: Tetrahydropyrimidine derivatives inhibit binding of a Tat-like, arginine-containing peptide, to HIV TAR RNA in vitro publication-title: FEBS Lett doi: 10.1016/0014-5793(95)00514-A contributor: fullname: Lapidot – volume: 72 start-page: 623 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0500 article-title: Extremolytes: natural compounds from extremophiles for versatile applications publication-title: Appl Microbiol Biotechnol doi: 10.1007/s00253-006-0553-9 contributor: fullname: Lentzen – volume: 335 start-page: 181 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0345 article-title: Successful small-bowel/liver transplantation publication-title: Lancet doi: 10.1016/0140-6736(90)90275-A contributor: fullname: Grant – volume: 564 start-page: 121 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0030 article-title: Inhibition of insulin amyloid formation by small stress molecules publication-title: FEBS Lett doi: 10.1016/S0014-5793(04)00326-6 contributor: fullname: Arora – volume: 78 start-page: 668 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0855 article-title: A new phytase expressed in yeast effectively improves the bioavailability of phytate phosphorous to weanling pigs publication-title: J Anim Sci doi: 10.2527/2000.783668x contributor: fullname: Stahl – volume: 120 start-page: 842 year: 2003 ident: 10.1016/j.biotechadv.2010.06.005_bb0265 article-title: Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro publication-title: J Invest Dermatol doi: 10.1046/j.1523-1747.2003.12148.x contributor: fullname: Fligiel – volume: 211 start-page: 213 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0875 article-title: The substrate-binding protein TeaA of the osmoregulated ectoine transporter TeaABC from Halomonas elongata: purification and characterization of recombinant TeaA publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.2002.tb11227.x contributor: fullname: Tetsch – volume: 6 start-page: 491 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0665 article-title: Intracellular ion and organic solute concentrations of the extremely halophilic bacterium Salinibacter ruber publication-title: Extremophiles doi: 10.1007/s00792-002-0286-3 contributor: fullname: Oren – volume: 3 start-page: 743 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0775 article-title: Osmoadaptation in Bacteria and Archaea: common principles and differences publication-title: Environ Microbiol doi: 10.1046/j.1462-2920.2001.00252.x contributor: fullname: Roessler – volume: 142 start-page: 195-01 year: 1996 ident: 10.1016/j.biotechadv.2010.06.005_bb0810 article-title: Compatible solutes in luminescent bacteria of the genera Vibrio, Photobacterium and Photorhabdus (Xenorhabdus): occurrence of ectoine, betaine and glutamate publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.1996.tb08430.x contributor: fullname: Schmitz – volume: 10 start-page: 716 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0795 article-title: Growth phase-dependent switch in osmolyte strategy in a moderate halophile: ectoine is a minor osmolyte but major stationary phase solute in Halobacillus halophilus publication-title: Environ Microbiol doi: 10.1111/j.1462-2920.2007.01494.x contributor: fullname: Saum – volume: 41 start-page: 13473 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0880 article-title: Protein hydration, thermodynamic binding, and preferential hydration publication-title: Biochemistry doi: 10.1021/bi020316e contributor: fullname: Timasheff – volume: 77 start-page: 2777 year: 1980 ident: 10.1016/j.biotechadv.2010.06.005_bb0885 article-title: Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.77.5.2777 contributor: fullname: Tolmasoff – volume: 111 start-page: 10231 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0965 article-title: Microscopic understanding of preferential exclusion of compatible solute ectoine publication-title: J Phys Chem B doi: 10.1021/jp068367z contributor: fullname: Yu – volume: 2 start-page: 10 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0240 article-title: Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure publication-title: Part Fibre Toxicol doi: 10.1186/1743-8977-2-10 contributor: fullname: Donaldson – volume: 37 start-page: 61 year: 1992 ident: 10.1016/j.biotechadv.2010.06.005_bb0515 article-title: Enzyme stabilization be ectoine-type compatible solutes: protection against heating, freezing and drying publication-title: Appl Microbiol Biotechnol doi: 10.1007/BF00174204 contributor: fullname: Lippert – volume: 3 start-page: 384 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0595 article-title: Body shaping under water stress: osmosensing and osmoregulation of solute transport in bacteria publication-title: Chembiochem doi: 10.1002/1439-7633(20020503)3:5<384::AID-CBIC384>3.0.CO;2-H contributor: fullname: Morbach – volume: 157 start-page: 693 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0805 article-title: High-yield cultivation of Marinococcus M52 for production and recovery of hydroxyectoine publication-title: Res Microbiol doi: 10.1016/j.resmic.2006.03.004 contributor: fullname: Schiraldi – ident: 10.1016/j.biotechadv.2010.06.005_bb0600 – volume: 22 start-page: 22-2 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0275 article-title: Protection of skin biological targets by different types of sunscreens publication-title: Photodermatol Photoimmunol Photomed doi: 10.1111/j.1600-0781.2006.00188.x contributor: fullname: Fourtanier – volume: 43 start-page: 326 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0785 article-title: Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis publication-title: Int J Dermatol doi: 10.1111/j.1365-4632.2004.02222.x contributor: fullname: Sander – volume: 54 start-page: 432 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0950 article-title: Role of water in some biological processes publication-title: Microbiol Rev doi: 10.1128/MMBR.54.4.432-449.1990 contributor: fullname: Wiggins – volume: 170 start-page: 291-06 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0735 article-title: Engineering for biosynthesis of ectoine (2-methyl 4-carboxy tetrahydro pyrimidine) in tobacco chloroplasts leads to accumulation of ectoine and enhanced salinity tolerance publication-title: Plant Sci doi: 10.1016/j.plantsci.2005.08.019 contributor: fullname: Rai – volume: 184 start-page: 3078 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0335 article-title: New type of osmoregulated solute transporter identified in halophilic members of the bacteria domain: TRAP transporter TeaABC mediates uptake of ectoine and hydroxyectoine in Halomonas elongata DSM 2581 (T) publication-title: J Bacteriol doi: 10.1128/JB.184.11.3078-3085.2002 contributor: fullname: Grammam – volume: 107 start-page: 124 year: 2010 ident: 10.1016/j.biotechadv.2010.06.005_bb0245 article-title: Process optimization of the integrated synthesis and secretion of ectoine and hydroxyectoine under hyper/hypo osmotic stress publication-title: Biotechnol Bioeng doi: 10.1002/bit.22750 contributor: fullname: Fallet – volume: 21 start-page: 1206 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0655 article-title: Optimization of ectoine synthesis through fed-batch fermentation of Brevibacterium epidermis publication-title: Biotechnol Progr doi: 10.1021/bp0500967 contributor: fullname: Onraedt – volume: 21 start-page: 531 year: 1997 ident: 10.1016/j.biotechadv.2010.06.005_bb0635 article-title: l(−)-Carnitine production with immobilized Escherichia coli cells in continuous reactors publication-title: Enzyme Microb Technol doi: 10.1016/S0141-0229(97)00063-X contributor: fullname: Obon – volume: 383 start-page: 945 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0820 article-title: The bacterial regulatory protein H-NS — a versatile modulator of nucleic acid publication-title: Biol Chem doi: 10.1515/BC.2002.101 contributor: fullname: Schroder – volume: 274 start-page: 33105 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0040 article-title: Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinity publication-title: J Biol Chem doi: 10.1074/jbc.274.46.33105 contributor: fullname: Azam – volume: 46 start-page: 28 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0375 article-title: Cloning of the ectoine biosynthesis gene ectABC from Halomonas sp. BYS-1 and salt stressed expression in Escherichia coli publication-title: Wei Sheng Wu Xue Bao contributor: fullname: He – volume: 208 start-page: 2819 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0960 article-title: Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses publication-title: J Exp Biol doi: 10.1242/jeb.01730 contributor: fullname: Yancey – volume: 73 start-page: 594-51 year: 2009 ident: 10.1016/j.biotechadv.2010.06.005_bb0530 article-title: Cohesion group approach for evolutionary analysis of aspartokinase, an enzyme that feeds a branched network of many biochemical pathways publication-title: Microbiol Mol Biol Rev doi: 10.1128/MMBR.00024-09 contributor: fullname: Lo – volume: 147 start-page: 46 year: 2010 ident: 10.1016/j.biotechadv.2010.06.005_bb0900 article-title: High productivity of ectoines by Halomonas boliviensis using a combined two-step fed-batch culture and milking process publication-title: J Biotechnol doi: 10.1016/j.jbiotec.2010.03.003 contributor: fullname: Van-Thuoc – volume: 69 start-page: 121 year: 1969 ident: 10.1016/j.biotechadv.2010.06.005_bb0745 article-title: Ectothiorhodospira halophila — a new species of genus Ectothiorhodospira publication-title: Arch Mikrobiol doi: 10.1007/BF00409756 contributor: fullname: Raymond – volume: 20 start-page: 170 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0285 article-title: Ectoine alters subcellular localization of inclusions and reduces apoptotic cell death induced by the truncated Machado–Joseph disease gene product with an expanded polyglutamine stretch publication-title: Neurobiol Dis doi: 10.1016/j.nbd.2005.02.011 contributor: fullname: Furusho – volume: 267 start-page: 125 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0510 article-title: The human heat-shock protein family. Expression of a novel heat-inducible Hsp70 (Hsp70B′) and isolation of its cDNA and genomic DNA publication-title: Biochem J doi: 10.1042/bj2670125 contributor: fullname: Leung – volume: 71 start-page: 157 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0690 article-title: The biosynthesis of ectoine publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.1990.tb03815.x contributor: fullname: Peters – volume: 68 start-page: 4328 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0560 article-title: Hydroxyectoine is superior to trehalose for anhydrobiotic engineering of Pseudomonas putida KT2440 publication-title: Appl Environ Microbiol doi: 10.1128/AEM.68.9.4328-4333.2002 contributor: fullname: Manzanera – volume: 366 start-page: 900 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0720 article-title: The role of LRP and H-NS in transcription regulation: involvement of synergism publication-title: J Mol Biol doi: 10.1016/j.jmb.2006.11.067 contributor: fullname: Pul – year: 2003 ident: 10.1016/j.biotechadv.2010.06.005_bb0460 contributor: fullname: Krutmann – volume: 64 start-page: 339 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0675 article-title: Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join publication-title: Am J Hum Genet doi: 10.1086/302269 contributor: fullname: Paulson – volume: 87 start-page: 8985 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0205 article-title: Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.87.22.8985 contributor: fullname: Cordingley – volume: 122 start-page: 1239 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0625 article-title: Ectoine, the compatible solute of Halomonas elongata, confers hyperosmotic tolerance in cultured tobacco cells publication-title: Plant Physiol doi: 10.1104/pp.122.4.1239 contributor: fullname: Nakayama – volume: 70 start-page: 3143 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0570 article-title: Plastic encapsulation of stabilized Escherichia coli and Pseudomonas putida publication-title: Appl Environ Microbiol doi: 10.1128/AEM.70.5.3143-3145.2004 contributor: fullname: Manzanera – volume: 7 start-page: 22 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0140 article-title: Ectoine added protection and care for the skin publication-title: Eur Cosmet contributor: fullname: Bunger – volume: 1 start-page: 5 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0770 article-title: Organic compatible solutes of halotolerant and halophilic microorganisms publication-title: Saline Systems doi: 10.1186/1746-1448-1-5 contributor: fullname: Roberts – volume: 15 start-page: 1019 year: 1981 ident: 10.1016/j.biotechadv.2010.06.005_bb0845 article-title: A spectrum response study on single strand DNA breaks, sister chromatid publication-title: Pediatr Res doi: 10.1203/00006450-198107000-00008 contributor: fullname: Sideris – volume: 44 start-page: 837 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0930 article-title: Ultraviolet A and melanoma: a review publication-title: J Am Acad Dermatol doi: 10.1067/mjd.2001.114594 contributor: fullname: Wang – volume: 38 start-page: 272 year: 1974 ident: 10.1016/j.biotechadv.2010.06.005_bb0480 article-title: Salt dependent properties of proteins from extremely halophilic bacteria publication-title: Bacteriol Rev doi: 10.1128/MMBR.38.3.272-290.1974 contributor: fullname: Lanyi – volume: 274 start-page: 15345 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0080 article-title: Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion publication-title: J Biol Chem doi: 10.1074/jbc.274.22.15345 contributor: fullname: Berneburg – year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0085 contributor: fullname: Bersch – volume: 280 start-page: 163 year: 1988 ident: 10.1016/j.biotechadv.2010.06.005_bb0525 article-title: Effects of UVB irradiation on epidermal adenylate cyclase responses in vitro publication-title: Arch Dermatol Res doi: 10.1007/BF00456848 contributor: fullname: Lizuka – volume: 23 start-page: 345 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0840 article-title: Growing E. coli to high cell density — a historical perspective on method development publication-title: Biotechnol Adv doi: 10.1016/j.biotechadv.2005.04.004 contributor: fullname: Shiloach – volume: 283 start-page: 7309 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0150 article-title: Intracellular organic osmolytes: function and regulation publication-title: J Biol Chem doi: 10.1074/jbc.R700042200 contributor: fullname: Burg – volume: 125 start-page: 545 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0350 article-title: Ultraviolet A-induced signaling involves a ceramide-mediated autocrine loop leading to ceramide de novo synthesis publication-title: J Invest Dermatol doi: 10.1111/j.0022-202X.2005.23782.x contributor: fullname: Grether-Beck – volume: 310 start-page: 955 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0105 article-title: The osmophobic effect: natural selection of a thermodynamic force in protein folding publication-title: J Mol Biol doi: 10.1006/jmbi.2001.4819 contributor: fullname: Bolen – volume: 45 start-page: 6 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0170 article-title: Relative importance of amino acids, glycine-betaine and ectoine synthesis in the biocontrol agent Pantoea agglomerans CPA-2 in response to osmotic, acidic and heat stress publication-title: Lett Appl Microbiol doi: 10.1111/j.1472-765X.2007.02156.x contributor: fullname: Canamas – volume: 43 start-page: 53-1 year: 1995 ident: 10.1016/j.biotechadv.2010.06.005_bb0280 article-title: Production of hydroxyectoine-high cell-density cultivation and osmotic downshock of Marinococcus strain M52 publication-title: J Biotechnol doi: 10.1016/0168-1656(95)00119-2 contributor: fullname: Frings – volume: 143 start-page: 1141 year: 1997 ident: 10.1016/j.biotechadv.2010.06.005_bb0535 article-title: Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli publication-title: Microbiology doi: 10.1099/00221287-143-4-1141 contributor: fullname: Louis – volume: 70 start-page: 3130 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0715 article-title: Functional expression of the ectoine hydroxylase gene (thpD) from Streptomyces chrysomallus in Halomonas elongata publication-title: Appl Environ Microbiol doi: 10.1128/AEM.70.5.3130-3132.2004 contributor: fullname: Prabhu – volume: 100 start-page: 98-07 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0910 article-title: Ectoines as compatible solutes and carbon and energy sources for the halophilic bacterium Chromohalobacter salexigens publication-title: J Appl Microbiol doi: 10.1111/j.1365-2672.2005.02757.x contributor: fullname: Vargas – volume: 4 start-page: 253 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0425 article-title: Mammalian cell desiccation: facing the challenges publication-title: Cell Preserv Technol doi: 10.1089/cpt.2006.9996 contributor: fullname: Kanias – volume: 10 start-page: 287-01 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0120 article-title: The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis publication-title: Antioxid Redox Signal doi: 10.1089/ars.2007.1897 contributor: fullname: Bringardner – volume: 91 start-page: 24 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0110 article-title: Genotoxicity of visible light (400–800 nm) and photoprotection assessment of ectoin, l-ergothioneine and mannitol and four sunscreens publication-title: J Photochem Photobiol doi: 10.1016/j.jphotobiol.2008.01.008 contributor: fullname: Botta – volume: 36 start-page: 239 year: 1965 ident: 10.1016/j.biotechadv.2010.06.005_bb0325 article-title: Senility of the face. Basic study to understand its causes and effects publication-title: Plast Reconstr Surg doi: 10.1097/00006534-196508000-00013 contributor: fullname: Gonzalez-Ulloa – volume: 102 start-page: 560 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0980 article-title: Supplementation effect of ectoine on thermostability of phytase publication-title: J Biosci Bioeng doi: 10.1263/jbb.102.560 contributor: fullname: Zhang – ident: 10.1016/j.biotechadv.2010.06.005_bb0440 – volume: 55 start-page: 1 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0730 article-title: Photoaging: mechanisms and repair publication-title: J Am Acad Dermatol doi: 10.1016/j.jaad.2005.05.010 contributor: fullname: Rabe – volume: 29 start-page: 173 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0590 article-title: Characterization of salt tolerance in ectoine-transformed tobacco plants (Nicotiana tabaccum): photosynthesis, osmotic adjustment, and nitrogen partitioning publication-title: Plant Cell Environ doi: 10.1111/j.1365-3040.2005.01410.x contributor: fullname: Moghaieb – volume: 150 start-page: 3051 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0165 article-title: Complex regulation of the synthesis of the compatible solute ectoine in the halophilic bacterium Chromohalobacter salexigens DSM 3043 publication-title: Microbiology doi: 10.1099/mic.0.27122-0 contributor: fullname: Calderon – year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0340 contributor: fullname: Grammel – volume: 5 start-page: D796 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0765 article-title: Osmoadaptation and osmoregulation in archaea publication-title: Front Biosci doi: 10.2741/roberts contributor: fullname: Roberts – volume: 21 start-page: 208 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0990 article-title: Bacterial translocation in acute rejection after small bowel transplantation in rats publication-title: Pediatr Surg Int doi: 10.1007/s00383-004-1321-5 contributor: fullname: Zou – volume: 8 start-page: 101 year: 1986 ident: 10.1016/j.biotechadv.2010.06.005_bb0750 article-title: Osmotic shock induced release of low molecular weight metabolites from free living and immobilized cyanobacteria publication-title: Enzyme Microb Technol doi: 10.1016/0141-0229(86)90080-3 contributor: fullname: Reed – volume: 66 start-page: 1572 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0055 article-title: Compatible-solute-supported periplasmic expression of functional recombinant proteins under stress conditions publication-title: Appl Environ Microbiol doi: 10.1128/AEM.66.4.1572-1579.2000 contributor: fullname: Barth – volume: 99 start-page: 941 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0615 article-title: Efficient cyclic system to yield ectoine using Brevibacterium sp. JCM 6894 subjected to osmotic downshock publication-title: Biotechnol Bioeng doi: 10.1002/bit.21619 contributor: fullname: Nagata – volume: 43 start-page: 219 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0210 article-title: Are freezing and dehydration similar stress vectors? A comparison of modes of interaction of stabilizing solutes with biomolecules publication-title: Cryobiology doi: 10.1016/0011-2240(90)90023-W contributor: fullname: Crowe – volume: 117A start-page: 357 year: 1997 ident: 10.1016/j.biotechadv.2010.06.005_bb0300 article-title: The kosmotropic (structure-forming) effect of compensatory solutes publication-title: Comp Biochem Physiol doi: 10.1016/S0300-9629(96)00275-7 contributor: fullname: Galinski – volume: 10 start-page: 197-03 issue: 3 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0145 article-title: Ectoine from halophilic microorganisms induces the expression of hsp70 and hsp70B′ in human keratinocytes modulating the proinflammatory response publication-title: Cell Stress Chaperones doi: 10.1379/CSC-101R.1 contributor: fullname: Buommino – volume: 84 start-page: 13 year: 2003 ident: 10.1016/j.biotechadv.2010.06.005_bb0045 article-title: Potential osmoprotectants for the lactic acid bacteria Pediococcus pentosaceus and Tetragenococcus halophila publication-title: Int J Food Microbiol doi: 10.1016/S0168-1605(02)00388-4 contributor: fullname: Baliarda – volume: 51 start-page: 760 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0640 article-title: High-density Escherichia coli cultures for continuous l(−)-carnitine production publication-title: Appl Microbiol Biotechnol doi: 10.1007/s002530051459 contributor: fullname: Obon – volume: 116 start-page: 313 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0005 article-title: Mammalian prion biology: one century of evolving concepts publication-title: Cell doi: 10.1016/S0092-8674(03)01031-6 contributor: fullname: Aguzzi – volume: 4 start-page: 1 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0130 article-title: The protective function of compatible solute ectoine on the skin cells and its biomolecules with respect to UV radiation, immunosuppression and membrane damage publication-title: IFSCC Mag contributor: fullname: Buenger – volume: 41 start-page: 684 year: 1994 ident: 10.1016/j.biotechadv.2010.06.005_bb0540 article-title: Survival of Escherichia coli during drying and storage in the presence of compatible solutes publication-title: Appl Microbiol Biotechnol doi: 10.1007/BF00167285 contributor: fullname: Louis – volume: 180 start-page: 29 year: 2009 ident: 10.1016/j.biotechadv.2010.06.005_bb0860 article-title: The compatible solute ectoine protects against nanoparticle-induced neutrophilic publication-title: Am J Respir Crit Care Med doi: 10.1164/rccm.200812-1911OC contributor: fullname: Sydlik – volume: 23 start-page: S22 issue: Suppl 1 year: 2000 ident: 10.1016/j.biotechadv.2010.06.005_bb0455 article-title: Ultraviolet A radiation-induced biological effects in human skin: relevance for photoaging and photodermatosis publication-title: J Dermatol Sci doi: 10.1016/S0923-1811(99)00077-8 contributor: fullname: Krutmann – volume: 21 start-page: 487 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0180 article-title: Characterization of the genes for the biosynthesis of the compatible solute ectoine in the moderately halophilic bacterium Halomonas elongata DSM 3043 publication-title: Syst Appl Microbiol doi: 10.1016/S0723-2020(98)80060-X contributor: fullname: Canovas – volume: 7 start-page: 82 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0575 article-title: Compatible solutes from hyperthermophiles improve the quality of DNA microarrays publication-title: BMC Biotechnol doi: 10.1186/1472-6750-7-82 contributor: fullname: Mascellani – volume: 62 start-page: 504 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0915 article-title: Biology of moderately halophilic aerobic bacteria publication-title: Microbiol Mol Biol Rev doi: 10.1128/MMBR.62.2.504-544.1998 contributor: fullname: Ventosa – volume: 30 start-page: 1403 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0740 article-title: Cloning and heterologous expression of ectoine biosynthesis genes from Bacillus halodurans in Escherichia coli publication-title: Biotechnol Lett doi: 10.1007/s10529-008-9688-3 contributor: fullname: Rajan – volume: 91 start-page: 288 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0620 article-title: Accumulation of ectoine in the halotolerant Brevibacterium sp. JCM 6894 publication-title: J Biosci Bioeng doi: 10.1016/S1389-1723(01)80136-5 contributor: fullname: Nagata – volume: 68 start-page: 93 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0360 article-title: Molecular characterization of a thermostable cyanophycin synthetase from the thermophilic cyanobacterium Synechococcus sp. strain MA19 and in vitro synthesis of cyanophycin and related polyamides publication-title: Appl Environ Microbiol doi: 10.1128/AEM.68.1.93-101.2002 contributor: fullname: Hai – volume: 101 start-page: 6433 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0060 article-title: Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0308633101 contributor: fullname: Bennion – volume: 233 start-page: 347 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0565 article-title: High survival and stability rates of Escherichia coli dried in hydroxyectoine publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.2004.tb09502.x contributor: fullname: Manzanera – volume: 95 start-page: 9268 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0725 article-title: Osmolyte-driven contraction of a random coil protein publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.95.16.9268 contributor: fullname: Qu – volume: 69 start-page: 5919 year: 2003 ident: 10.1016/j.biotechadv.2010.06.005_bb0705 article-title: Role of ectoine in Vibrio cholerae osmoadaptation publication-title: Appl Environ Microbiol doi: 10.1128/AEM.69.10.5919-5927.2003 contributor: fullname: Pflughoeft – volume: 23 start-page: 40 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0400 article-title: Ethanol fermentation on the move publication-title: Nat Biotechnol doi: 10.1038/nbt0105-40 contributor: fullname: Jeffries – volume: 272 start-page: 25794-01 year: 1997 ident: 10.1016/j.biotechadv.2010.06.005_bb0185 article-title: Isolation and characterization of salt-sensitive mutants of the moderate halophile Halomonas elongata and cloning of the ectoine synthesis genes publication-title: J Biol Chem doi: 10.1074/jbc.272.41.25794 contributor: fullname: Canovas – volume: 90 start-page: 10962 year: 1993 ident: 10.1016/j.biotechadv.2010.06.005_bb0670 article-title: Conversion of alpha-helices into beta-sheets features in the formation of the publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.90.23.10962 contributor: fullname: Pan – volume: 51 start-page: 422 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0755 article-title: High-cell-density cultivation of microorganisms publication-title: Appl Microbiol Biotechnol doi: 10.1007/s002530051412 contributor: fullname: Riesenberg – volume: 4 start-page: 6 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0475 article-title: Compatible solute influence on nucleic acids: many questions but few answers publication-title: Saline Sys doi: 10.1186/1746-1448-4-6 contributor: fullname: Kurz – volume: 62 start-page: 90 year: 2010 ident: 10.1016/j.biotechadv.2010.06.005_bb0935 article-title: Ectoine improves yield of biodiesel catalyzed by immobilized lipase publication-title: J Mol Catal Enzym doi: 10.1016/j.molcatb.2009.09.014 contributor: fullname: Wang – volume: 388 start-page: 316 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0970 article-title: Slowdown of water diffusion around protein in aqueous solution with ectoine publication-title: Chem Phys Lett doi: 10.1016/j.cplett.2004.02.104 contributor: fullname: Yu – volume: 66 start-page: 385-07 year: 1997 ident: 10.1016/j.biotechadv.2010.06.005_bb0370 article-title: Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins publication-title: Annu Rev Biochem doi: 10.1146/annurev.biochem.66.1.385 contributor: fullname: Harper – volume: 408 start-page: 137 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0695 article-title: Oxidative DNA damage induced by visible light in mammalian cells: extent publication-title: Mutat Res doi: 10.1016/S0921-8777(98)00029-9 contributor: fullname: Pflaum – volume: 29 start-page: 397-07 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0710 article-title: Regulation of compatible solute accumulation in bacteria publication-title: Mol Microbiol doi: 10.1046/j.1365-2958.1998.00875.x contributor: fullname: Poolman – volume: 12 start-page: 391-04 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0050 publication-title: Extremophiles doi: 10.1007/s00792-008-0142-1 contributor: fullname: Banciu – volume: 94 start-page: 384 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0610 article-title: Effect of compatible solutes on the respiratory activity and growth of Escherichia coli K-12 under NaCl stress publication-title: J Biosci Bioeng doi: 10.1016/S1389-1723(02)80213-4 contributor: fullname: Nagata – volume: 362 start-page: 543 year: 1993 ident: 10.1016/j.biotechadv.2010.06.005_bb0270 article-title: Neurotoxicity of a prion protein fragment publication-title: Nature doi: 10.1038/362543a0 contributor: fullname: Forloni – volume: 9 start-page: 4145 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0230 article-title: Skinner MA.HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure publication-title: EMBO J doi: 10.1002/j.1460-2075.1990.tb07637.x contributor: fullname: Dingwall – volume: 365 start-page: 808 year: 2008 ident: 10.1016/j.biotechadv.2010.06.005_bb0415 article-title: Small stress molecules inhibit aggregation and neurotoxicity of prion peptide 106–126 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2007.11.074 contributor: fullname: Kanapathipillai – volume: 214 start-page: 101 year: 2003 ident: 10.1016/j.biotechadv.2010.06.005_bb0190 article-title: Membrane cell retention systems for continuous production of l-carnitine using Proteus sp publication-title: J Membr Sci doi: 10.1016/S0376-7388(02)00539-2 contributor: fullname: Canovas – ident: 10.1016/j.biotechadv.2010.06.005_bb0405 doi: 10.1002/3527600035.bpol7007 – volume: 36 start-page: 9101 year: 1997 ident: 10.1016/j.biotechadv.2010.06.005_bb0925 article-title: A naturally occurring protective system in urea-rich cells: mechanism of osmolyte publication-title: Biochemistry doi: 10.1021/bi970247h contributor: fullname: Wang – volume: 19 start-page: 306 year: 1982 ident: 10.1016/j.biotechadv.2010.06.005_bb0200 article-title: Cellular responses to extreme water loss: the water-replacement hypothesis publication-title: Cryobiology doi: 10.1016/0011-2240(82)90159-6 contributor: fullname: Clegg – volume: 144 start-page: 260 year: 2001 ident: 10.1016/j.biotechadv.2010.06.005_bb0850 article-title: Treatment with 815-nm diode laser induces long-lasting expression of 72-kDa heat publication-title: Br J Dermatol doi: 10.1046/j.1365-2133.2001.04010.x contributor: fullname: Souil – volume: 153 start-page: 607 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0290 article-title: The role of trehalose as a substitute for nitrogen-containing compatible solutes (Ectothiorhodospira halochloris) publication-title: Arch Microbiol doi: 10.1007/BF00245273 contributor: fullname: Galinski – volume: 61 start-page: 117 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0220 article-title: An overview of the role and diversity of compatible solutes in Bacteria and Archaea publication-title: Adv Biochem Eng Biotechnol contributor: fullname: da Costa – volume: 8 start-page: 175 year: 2004 ident: 10.1016/j.biotechadv.2010.06.005_bb0920 article-title: Marinococcus halophilus DSM 20408T encodes two transporters for compatible solutes belonging to the betaine-carnitine-choline transporter family: identification and characterization of ectoine transporter EctM and glycine betaine transporter BetM publication-title: Extremophiles doi: 10.1007/s00792-004-0375-6 contributor: fullname: Vermeulen – volume: 1764 start-page: 1234 year: 2006 ident: 10.1016/j.biotechadv.2010.06.005_bb0445 article-title: Compatible solutes as protectants for zymogens against proteolysis publication-title: Biochim Biophys Acta doi: 10.1016/j.bbapap.2006.04.015 contributor: fullname: Kolp – volume: 18 start-page: 443 year: 1988 ident: 10.1016/j.biotechadv.2010.06.005_bb0895 article-title: Production, rapid purification and catalytic characterization of extracellular publication-title: Prep Biochem doi: 10.1080/00327488808062543 contributor: fullname: Ullah – volume: 68 start-page: 554 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0450 article-title: Ischaemia–reperfusion injury to the intestine publication-title: Aust N Z J Surg doi: 10.1111/j.1445-2197.1998.tb02099.x contributor: fullname: Kong – volume: 24 start-page: 58-3 year: 1999 ident: 10.1016/j.biotechadv.2010.06.005_bb0680 article-title: Glutamine repeats and neurodegenerative diseases: molecular aspects publication-title: Trends Biochem Sci doi: 10.1016/S0968-0004(98)01350-4 contributor: fullname: Perutz – volume: 4 start-page: 1365 year: 1990 ident: 10.1016/j.biotechadv.2010.06.005_bb0780 article-title: A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated publication-title: Genes Dev doi: 10.1101/gad.4.8.1365 contributor: fullname: Roy – ident: 10.1016/j.biotechadv.2010.06.005_bb0305 – volume: 57 start-page: 306 year: 1998 ident: 10.1016/j.biotechadv.2010.06.005_bb0790 article-title: Bacterial milking: a novel bioprocess for production of compatible solutes publication-title: Biotechnol Bioeng doi: 10.1002/(SICI)1097-0290(19980205)57:3<306::AID-BIT7>3.0.CO;2-L contributor: fullname: Sauer – volume: 28 start-page: 479-13 year: 2007 ident: 10.1016/j.biotechadv.2010.06.005_bb0545 article-title: Pathogenesis of chronic obstructive pulmonary disease publication-title: Clin Chest Med doi: 10.1016/j.ccm.2007.06.008 contributor: fullname: Macnee – volume: 6 start-page: 15 year: 2002 ident: 10.1016/j.biotechadv.2010.06.005_bb0090 article-title: Investigation into a stress-inducible promoter region from Marinococcus halophilus using green fluorescent protein publication-title: Extremophiles doi: 10.1007/s007920100212 contributor: fullname: Bestvater – volume: 579 start-page: 4775 year: 2005 ident: 10.1016/j.biotechadv.2010.06.005_bb0420 article-title: Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer's beta-amyloid publication-title: FEBS Lett doi: 10.1016/j.febslet.2005.07.057 contributor: fullname: Kanapathipillai – year: 2009 ident: 10.1016/j.biotechadv.2010.06.005_bb0905 article-title: Ectoine production by Halomonas boliviensis: optimization using response surface methodology publication-title: Mar Biotechnol (NY) contributor: fullname: Van-Thuoc – volume: 178 start-page: 385 year: 1996 ident: 10.1016/j.biotechadv.2010.06.005_bb0555 article-title: Induction of synthesis of tetrahydropyrimidine derivatives in Streptomyces publication-title: J Bacteriol doi: 10.1128/jb.178.2.385-395.1996 contributor: fullname: Malin |
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SubjectTerms | Abiotic stress protection Amino Acids, Diamino - biosynthesis Amino Acids, Diamino - chemistry Animals Bacteria Bacterial milking Bioengineering Biological and medical sciences Bioreactors Biotechnology Cells - metabolism Compatible solutes Cytoprotection Diseases Ectoine Fundamental and applied biological sciences. Psychology Halophiles Humans Hydroxyectoine Macromolecules Methods. Procedures. Technologies Microorganisms Reactor design Receiving Spreads Strategy Stress, Physiological Stresses Various methods and equipments |
Title | Ectoines in cell stress protection: Uses and biotechnological production |
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