Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes

• Published in: Brain (London, England : 1878) Vol. 137; no. Pt 6; pp. 1579 - 1613
• Main Authors: EDWARDS, Timothy J, SHERR, Elliott H, BARKOVICH, A. James, RICHARDS, Linda J
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.06.2014
• Series: Editor's Choice
• Subjects: Agenesis of Corpus Callosum - genetics; Agenesis of Corpus Callosum - physiopathology; Animals; Biological and medical sciences; Corpus Callosum - growth & development; Corpus Callosum - pathology; Disease Models, Animal; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes; Genetic Predisposition to Disease - genetics; Humans; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Mutation - genetics; Nervous system; Nervous system (semeiology, syndromes); Neurology; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Review; Guidance; Nervous system diseases; midline patterning; Central nervous system disease; neurogenesis; Axon; axon guidance; neuronal specification; Corpus callosum syndrome; Corpus callosum; Cerebral disorder; corpus callosum

The corpus callosum is the largest fibre tract in the brain, connecting the two cerebral hemispheres, and thereby facilitating the integration of motor and sensory information from the two sides of the body as well as influencing higher cognition associated with executive function, social interactio...