Platon: identification and characterization of bacterial plasmid contigs in short-read draft assemblies exploiting protein sequence-based replicon distribution scores

• Published in: Microbial genomics Vol. 6; no. 10
• Main Authors: Schwengers, Oliver, Barth, Patrick, Falgenhauer, Linda, Hain, Torsten, Chakraborty, Trinad, Goesmann, Alexander
• Format: Journal Article
• Language: English
• Published: England Microbiology Society 01.10.2020
• Subjects: Bacterial Proteins - genetics; Chromosomes, Bacterial - genetics; Computational Biology - methods; Contig Mapping - methods; Drug Resistance, Multiple, Bacterial - genetics; Escherichia coli - genetics; Genome, Bacterial - genetics; High-Throughput Nucleotide Sequencing; Plasmids - genetics; Software; Whole Genome Sequencing; NGS; plasmids; bacteria; whole-genome sequencing

Plasmids are extrachromosomal genetic elements that replicate independently of the chromosome and play a vital role in the environmental adaptation of bacteria. Due to potential mobilization or conjugation capabilities, plasmids are important genetic vehicles for antimicrobial resistance genes and v...