Risk factors for progression in children and young adults with IgA nephropathy: an analysis of 261 cases from the VALIGA European cohort

• Published in: Pediatric nephrology (Berlin, West) Vol. 32; no. 1; pp. 139 - 150
• Main Authors: Coppo, Rosanna, Lofaro, Danilo, Camilla, Roberta R, Bellur, Shubha, Cattran, Daniel, Cook, H. Terence, Roberts, Ian S. D., Peruzzi, Licia, Amore, Alessandro, Emma, Francesco, Fuiano, Laura, Berg, Ulla, Topaloglu, Rezan, Bilginer, Yelda, Gesualdo, Loreto, Polci, Rosaria, Mizerska-Wasiak, Malgorzata, Caliskan, Yasar, Lundberg, Sigrid, Cancarini, Giovanni, Geddes, Colin, Wetzels, Jack, Wiecek, Andrzej, Durlik, Magdalena, Cusinato, Stefano, Rollino, Cristiana, Maggio, Milena, Praga, Manuel, K.Smerud, Hilde, Tesar, Vladimir, Maixnerova, Dita, Barratt, Jonathan, Papalia, Teresa, Bonofiglio, Renzo, Mazzucco, Gianna, Giannakakis, Costantinos, Soderberg, Magnus, Orhan, Diclehan, Di Palma, Anna Maria, Maldyk, Jadwiga, Ozluk, Yasemin, Sudelin, Birgitta, Tardanico, Regina, Kipgen, David, Steenbergen, Eric, Karkoszka, Henryk, Perkowska-Ptasinska, Agnieszka, Ferrario, Franco, Gutierrez, Eduardo, Honsova, Eva
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2017; Springer Nature B.V
• Subjects: Adrenal Cortex Hormones - therapeutic use; Age Factors; Biopsy; Child; Child, Preschool; Classification; Cohort Studies; Disease Progression; Endpoint Determination; Europe - epidemiology; Female; Glomerular Filtration Rate; Glomerulonephritis, IGA - drug therapy; Glomerulonephritis, IGA - epidemiology; Glomerulonephritis, IGA - pathology; Humans; IgA nephropathy; Immunosuppressive Agents; Infant; Kidney - pathology; Kidney diseases; Kidney Failure, Chronic - epidemiology; Kidney Failure, Chronic - pathology; Male; Medicine; Medicine & Public Health; Nephrology; Original Article; Pathology; Pathology classification; Pediatrics; Progression; Proteinuria; Proteinuria - epidemiology; Proteinuria - pathology; Remission (Medicine); Retrospective Studies; Risk Factors; Sex Factors; Survival Analysis; Urology; Young adults; Poland; Istanbul Turkey; Italy; Sweden; Turkey; United Kingdom > UK; Progression; IgA nephropathy; Pathology classification; Risk factors; Proteinuria

Background There is a need for early identification of children with immunoglobulin A nephropathy (IgAN) at risk of progression of kidney disease. Methods Data on 261 young patients [age <23 years; mean follow-up of 4.9 (range 2.5–8.1) years] enrolled in VALIGA, a study designed to validate the O...