Cortical thickness analysis examined through power analysis and a population simulation

• Published in: NeuroImage (Orlando, Fla.) Vol. 24; no. 1; pp. 163 - 173
• Main Authors: Lerch, Jason P., Evans, Alan C.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 2005; Elsevier Limited
• Subjects: Accuracy; Algorithms; Artificial Intelligence; Automation; Cephalometry - statistics & numerical data; Cerebral Cortex - anatomy & histology; Computer Graphics; Computer Simulation; Fingers & toes; Humans; Imaging, Three-Dimensional; Mathematical Computing; Neurosciences; Normal Distribution; Probability Theory; Reference Values; Reproducibility of Results; Signal Processing, Computer-Assisted; Simulation; Sports injuries; Studies; Surface Properties

We have previously developed a procedure for measuring the thickness of cerebral cortex over the whole brain using 3-D MRI data and a fully automated surface-extraction (ASP) algorithm. This paper examines the precision of this algorithm, its optimal performance parameters, and the sensitivity of th...