Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer - Bates, Paula J.; Laber, Damian A.; Miller, Donald M.; Thomas, Shelia D.; Trent, John O. (Experimental and molecular pathology, 2009)
Keywords: Animals; Antineoplastic Agents - chemistry; Antineoplastic Agents - therapeutic use; Aptamer; Aptamers, Nucleotide; AS1411; Cell Proliferation - drug effects; Clinical Trials as Topic; Drug Discovery; Drug Screening Assays, Antitumor; Dz13; G-quartets; G-rich oligonucleotides; Humans; Molecular Structure; Neoplasms - drug therapy; Neoplasms - metabolism; Neoplasms - pathology; NF-kappaB; Nucleolin; Oligodeoxyribonucleotides - chemistry; Oligodeoxyribonucleotides - therapeutic use; Phosphoproteins - drug effects; Phosphoproteins - metabolism; PRMT5; Quadruplex; RNA-Binding Proteins - drug effects; RNA-Binding Proteins - metabolism; T-oligos; T-oligos; PRMT5; G-rich oligonucleotides; AS1411; Dz13; Aptamer; NF-kappaB; Quadruplex; G-quartets; Nucleolin