Giant Glial Cell: New Insight Through Mechanism-Based Modeling

• Published in: Journal of biological physics Vol. 34; no. 3-4; pp. 441 - 457
• Main Authors: Postnov, D. E, Ryazanova, L. S, Brazhe, N. A, Brazhe, A. R, Maximov, G. V, Mosekilde, E, Sosnovtseva, O. V
• Format: Journal Article
• Language: English
• Published: Dordrecht Dordrecht : Springer Netherlands 01.08.2008; Springer Netherlands; Springer Nature B.V
• Subjects: Biochemistry; Biological and Medical Physics; Biophysics; Cellular biology; Complex Fluids and Microfluidics; Complex Systems; Glia; Hirudinea; Hirudo medicinalis; Neuron; Neurons; Neurosciences; Original Paper; Physics; Physics and Astronomy; Soft and Granular Matter; Tripartite synapse; Neuron; Glia; Modeling; Tripartite synapse

The paper describes a detailed mechanism-based model of a tripartite synapse consisting of P- and R-neurons together with a giant glial cell in the ganglia of the medical leech (Hirudo medicinalis), which is a useful object for experimental studies in situ. We describe the two main pathways of the g...