Neuropeptide Y and its receptors in ventricular endocardial endothelial cells

• Published in: Canadian journal of physiology and pharmacology Vol. 95; no. 10; pp. 1224 - 1229
• Main Authors: Jacques, Danielle, D’Orléans-Juste, Pedro, Magder, Sheldon, Bkaily, Ghassan
• Format: Journal Article
• Language: English
• Published: Canada NRC Research Press 01.10.2017; Canadian Science Publishing NRC Research Press
• Subjects: Animals; Cardiovascular disease; Cardiovascular Diseases - metabolism; Cardiovascular Diseases - pathology; Cardiovascular Diseases - physiopathology; Endocardium - metabolism; Endocardium - pathology; Endocardium - physiopathology; Endothelial cells; Endothelial Cells - metabolism; Endothelial Cells - pathology; Endothelium; Heart; Heart diseases; Heart Ventricles - metabolism; Heart Ventricles - pathology; Heart Ventricles - physiopathology; Humans; Neuropeptide Y; Neuropeptide Y - metabolism; Neuropeptides; Pharmacology; Physiological aspects; Physiology; Receptors, Neuropeptide Y - metabolism; Signal Transduction; Ventricle; Canada; endocardial endothelial cells; ET-1; calcium; NPY; récepteurs du NPY; NPY receptors; cellules endothéliales endocardiques

Endocardial endothelial cells (EECs) constitute an important component of the heart. These cells form a monolayer that covers the cavities of the right (EECRs) and left (EECLs) ventricles. They play an important role in cardiac excitation–contraction coupling via their secretion of cardioactive fact...