Common Nodes of Virus–Host Interaction Revealed Through an Integrated Network Analysis

• Published in: Frontiers in immunology Vol. 10; p. 2186
• Main Authors: Bösl, Korbinian, Ianevski, Aleksandr, Than, Thoa T., Andersen, Petter I., Kuivanen, Suvi, Teppor, Mona, Zusinaite, Eva, Dumpis, Uga, Vitkauskiene, Astra, Cox, Rebecca J., Kallio-Kokko, Hannimari, Bergqvist, Anders, Tenson, Tanel, Merits, Andres, Oksenych, Valentyn, Bjørås, Magnar, Anthonsen, Marit W., Shum, David, Kaarbø, Mari, Vapalahti, Olli, Windisch, Marc P., Superti-Furga, Giulio, Snijder, Berend, Kainov, Denis, Kandasamy, Richard K.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 04.10.2019
• Subjects: gene-drug interaction; Immunology; innate immunity; molecular innate immunity; network analysis; protein-protein interaction; viral evasion; virus-host interaction; viral evasion; innate immunity; gene–drug interaction; protein–protein interaction; molecular innate immunity; network analysis; virus–host interaction

Viruses are one of the major causes of acute and chronic infectious diseases and thus a major contributor to the global burden of disease. Several studies have shown how viruses have evolved to hijack basic cellular pathways and evade innate immune response by modulating key host factors and signali...