Effect of Aldosterone Antagonism on Exercise Tolerance in Heart Failure With Preserved Ejection Fraction - Kosmala, Wojciech; Rojek, Aleksandra; Przewlocka-Kosmala, Monika; Wright, Leah; Mysiak, Andrzej; Marwick, Thomas H. (Journal of the American College of Cardiology, 2016)
Keywords: Age; Aged; aldosterone antagonism; Blood Flow Velocity; Blood pressure; Cardiology; Cardiovascular; Cardiovascular disease; Diabetes; Double-Blind Method; echocardiography; Exercise Tolerance - drug effects; Female; Fitness equipment; Fractions; Heart failure; Heart Failure - physiopathology; heart failure with preserved ejection fraction; Humans; Hypertension; left ventricular filling pressure; Male; Mineralocorticoid Receptor Antagonists - therapeutic use; Mitral Valve - physiopathology; Mortality; Prospective Studies; Spironolactone - therapeutic use; Stroke Volume - drug effects; echocardiography; FP; peak VO2; HFpEF; left ventricular filling pressure; GLS; aldosterone antagonism; OUES; heart failure with preserved ejection fraction; LA; VAC; MRA; HF; RER; heart failure; left atrial; peak VO 2; global longitudinal myocardial deformation; mineralocorticoid receptor antagonism; oxygen-uptake efficiency slope; ventriculo-arterial coupling; peak oxygen uptake; filling pressure; respiratory exchange ratio