Impact of defined cell envelope mutations in Escherichia coli on the in vitro antibacterial activity of avibactam/β-lactam combinations - McLeod, Sarah M.; Patey, Sara A.; Huband, Michael D.; Nichols, Wright W. (International journal of antimicrobial agents, 2017)
Keywords: Anti-Bacterial Agents - pharmacology; antibacterial properties; antibiotic resistance; Azabicyclo Compounds - pharmacology; aztreonam; beta-lactamase; beta-Lactamase Inhibitors - pharmacology; beta-Lactams - pharmacology; ceftazidime; Cell envelope; Cell Membrane - genetics; Cell Wall - genetics; Efflux; Escherichia coli; Escherichia coli - drug effects; Escherichia coli - genetics; Gene Deletion; Gram-negative bacteria; Gram-negative infection; hydrophilicity; Infectious Disease; lipopolysaccharides; Lipopolysaccharides - genetics; Microbial Sensitivity Tests; minimum inhibitory concentration; mutants; Mutation; porins; Porins - genetics; solutes; β-Lactam; β-Lactamase; Gram-negative infection; Efflux; β-Lactam; β-Lactamase; Cell envelope