Feasibility of simultaneous whole-brain imaging on an integrated PET-MRI system using an enhanced 2-point Dixon attenuation correction method

• Published in: Frontiers in neuroscience Vol. 8; p. 434
• Main Authors: Anazodo, Udunna C, Thiessen, Jonathan D, Ssali, Tracy, Mandel, Jonathan, Günther, Matthias, Butler, John, Pavlosky, William, Prato, Frank S, Thompson, R Terry, St Lawrence, Keith S
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 05.01.2015; Frontiers Media S.A
• Subjects: Accuracy; Algorithms; Arterial Spin Labeling; ASL; Bone imaging; Brain mapping; Brain research; cerebral blood flow; Computed tomography; FDG; glucose uptake; Image processing; Magnetic resonance imaging; Medical imaging; Methods; Neuroimaging; Neuroscience; NMR; Nuclear magnetic resonance; Oncology; Perfusion; PET-MRI; Positron emission tomography; Segmentation; Spin labeling; Canada; PET-MRI; attenuation correction; glucose uptake; 18F-fluorodexoyglucose; FDG; cerebral blood flow; ASL; arterial spin labeling

To evaluate a potential approach for improved attenuation correction (AC) of PET in simultaneous PET and MRI brain imaging, a straightforward approach that adds bone information missing on Dixon AC was explored. Bone information derived from individual T1-weighted MRI data using segmentation tools i...