Targeting heptad repeats and fusion peptide: nanoparticle vaccine elicits mucosal immune response against SARS-CoV-2 variants - Liang, Chaofeng; Li, Rong; Pu, Zeyu; Chen, Ran; Li, Yuzhuang; Chen, Siqi; Feng, Jinzhu; Liu, Jie; Bai, Yuteng; Qin, Xuewen; Xie, Chengjie; Zhang, Yixin; et al. (Journal of nanobiotechnology, 2025)
Keywords: Administration, Intranasal; Animals; Antibodies, Viral - immunology; Antigenic determinants; Broad-spectrum vaccine; Bronchoalveolar Lavage Fluid - immunology; Conserved epitopes; COVID-19 - immunology; COVID-19 - prevention & control; COVID-19 - virology; COVID-19 Vaccines - administration & dosage; COVID-19 Vaccines - immunology; Female; Health aspects; Humans; Immune response; Immunity, Mucosal - immunology; Immunoglobulin G - immunology; Lung - immunology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mucosal immunity; Nanoparticle vaccine; Nanoparticles; Nanoparticles - administration & dosage; Nanoparticles - chemistry; Nanovaccines; Peptides; Pharmaceutical research; Respiratory viruses; SARS-CoV-2; SARS-CoV-2 - immunology; Spike Glycoprotein, Coronavirus - chemistry; Spike Glycoprotein, Coronavirus - immunology; China; Respiratory viruses; Broad-spectrum vaccine; Conserved epitopes; SARS-CoV-2; Mucosal immunity; Nanoparticle vaccine