Protein Structural Change in a Mixed System of Ionic and Zwitterionic Surfactants

• Published in: Journal of Oleo Science Vol. 60; no. 5; pp. 229 - 236
• Main Authors: Moriyama, Yoshiko, Razali, Azaima, Tanaka, Michihito, Takeda, Kunio
• Format: Journal Article
• Language: English
• Published: Japan Japan Oil Chemists' Society 2011; Japan Science and Technology Agency
• Subjects: Animals; binary surfactant system; bovine serum albumin; Cattle; Ions - chemistry; Micelles; N-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate; protein structure; Protein Structure, Secondary; Serum Albumin, Bovine - chemistry; sodium dodecyl sulfate; Sodium Dodecyl Sulfate - chemistry; Surface-Active Agents - chemistry

The secondary structure of bovine serum albumin (BSA) in the binary surfactant system of anionic sodium dodecyl sulfate (SDS) and zwitterionic N-dodecyl-N,N-dimethyl-3-ammonio-1- propanesulfonate (DDAPS) was examined at 25°C. The helicity of BSA decreased from 66% to 55% in a solution of DDAPS alone...