Protein expression and gene polymorphism of CXCL10 in patients with colorectal cancer

• Published in: Biomedical reports Vol. 2; no. 3; pp. 340 - 343
• Main Authors: DIMBERG, JAN, SKARSTEDT, MARITA, LÖFGREN, STURE, ZAR, NIKLAS, MATUSSEK, ANDREAS
• Format: Journal Article
• Language: English
• Published: England D.A. Spandidos 01.05.2014; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: Age; Angiogenesis; Attraction; Blood & organ donations; Cancer; Chemokines; Classification; Colorectal cancer; Colorectal carcinoma; CXCL10; CXCL10 protein; Cytokines; Dendritic cells; Deoxyribonucleic acid; Disease control; DNA; Fibroblasts; Gene expression; Gene polymorphism; Genetic aspects; Genetic polymorphisms; Genetic testing; Genotype & phenotype; Health aspects; Medicin och hälsovetenskap; Metastases; Patients; Plasma levels; Plasmas (physics); Polymorphism; Protein expression; Proteins; Single-nucleotide polymorphism; Technology assessment; Tumors; CXCL10; gene polymorphism; colorectal cancer; protein expression

Chemokines (chemotactic cytokines) promote leukocyte attraction to sites of inflammation and cancer. Certain chemokines promote and regulate neoplastic progression, including metastasis and angiogenesis. One such chemokine, CXCL10, was found to be expressed in colorectal cancer (CRC) tissue. To gain...