Synchronous Breast Implant–associated Anaplastic Large Cell Lymphoma and Invasive Carcinoma: Genomic Profiling and Management Implications

• Published in: Plastic and reconstructive surgery. Global open Vol. 7; no. 4; p. e2188
• Main Authors: Mukhtar, Rita A, Holland, Michael, Sieber, David A, Wen, Kwun Wah, Rugo, Hope S, Kadin, Marshall E, Bean, Gregory R
• Format: Journal Article
• Language: English
• Published: United States Copyright The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Plastic Surgeons. All rights reserved 01.04.2019; Wolters Kluwer Health; Wolters Kluwer
• Subjects: Original

A 59-year-old woman with a history of cosmetic implants developed ipsilateral synchronous breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) and invasive ductal carcinoma in the left breast. Each tumor was subjected to next-generation sequencing, and separate analyses revealed mutua...