DYNAMIC MR IMAGING, BIODISTRIBUTION AND PHARMACOKINETICS OF POLYMER SHELLED MICROBUBBLES CONTAINING SPION

• Published in: Nano : brief reports and reviews Vol. 9; no. 6; p. 1450069
• Main Authors: BARREFELT, ÅSA, PARADOSSI, GAIO, ASEM, HEBA, MARGHERITELLI, SILVIA, SAGHAFIAN, MARYAM, ODDO, LETIZIA, MUHAMMED, MAMOUN, ASPELIN, PETER, HASSAN, MOUSTAPHA, BRISMAR, TORKEL B.
• Format: Journal Article
• Language: English
• Published: Singapore World Scientific Publishing Company 01.08.2014; World Scientific; World Scientific Publishing Co. Pte., Ltd
• Subjects: biodistribution; Condensed matter: electronic structure, electrical, magnetic, and optical properties; Construction standards; Contrast agents; Diagnostic systems; dynamic MR imaging; Exact sciences and technology; Half-life; Imaging; Iron oxides; Liver; Lungs; Macrophages; Magnetic properties and materials; Magnetic resonance imaging; Mathematical models; Medical imaging; microbubbles; Nanoparticles; Nanostructure; NMR; Nuclear magnetic resonance; Organs; Pharmacokinetics; Pharmacology; Physics; Pigments; Rats; Small particles and nanoscale materials; SPION; Spleen; Studies of specific magnetic materials; superparamagnetic iron oxide nanoparticles; Time measurement; biodistribution; microbubbles; Magnetic resonance imaging; dynamic MR imaging; superparamagnetic iron oxide nanoparticles; pharmacokinetics; SPION; Morphological changes; Iron oxide; NMR imaging; Magnetic nanomaterial; Macrophages; Agarose; super-paramagnetic iron oxide nanoparticles; Nanoparticles; Relaxation; Magnetic particles; Imaging; Polymers

Magnetic Resonance Imaging (MRI) is a noninvasive diagnostic method that provides information on morphological and physiological changes of the internal organs over time. Imaging and measurements can be repeated on the same subject, thereby reducing inter-individual variability effects and hence the...