Derivation and Cloning of a Novel Rhesus Embryonic Stem Cell Line Stably Expressing Tau‐Green Fluorescent Protein

Embryonic stem cells (ESC) have the ability of indefinite self‐renewal and multilineage differentiation, and they carry great potential in cell‐based therapies. The rhesus macaque is the most relevant preclinical model for assessing the benefit, safety, and efficacy of ESC‐based transplantations in...

Full description

Saved in:

Bibliographic Details
Published in	Stem cells (Dayton, Ohio) Vol. 26; no. 6; pp. 1444 - 1453
Main Authors	Wianny, Florence, Bernat, Agnieszka, Huissoud, Cyril, Marcy, Guillaume, Markossian, Suzy, Cortay, Véronique, Giroud, Pascale, Leviel, Vincent, Kennedy, Henry, Savatier, Pierre, Dehay, Colette
Format	Journal Article
Language	English
Published	Bristol John Wiley & Sons, Ltd 01.06.2008 Alphamed Press AlphaMed Press
Subjects	Alkaline Phosphatase Alkaline Phosphatase - metabolism Animals Blastocyst Blastocyst - cytology Cell Differentiation Cell Line Cellular Biology Embryonic Stem Cells Embryonic Stem Cells - cytology Embryonic Stem Cells - enzymology Embryonic Stem Cells - physiology Embryonic Stem Cells - virology Genes, Reporter Green fluorescent protein Green Fluorescent Proteins Green Fluorescent Proteins - genetics Lentivirus Life Sciences Macaca mulatta Primates Reverse Transcriptase Polymerase Chain Reaction Rhesus monkey Stem Cell Transplantation Stem Cell Transplantation - methods tau Proteins tau Proteins - genetics Teratoma Teratoma - genetics Teratoma - pathology Transfection Zona Pellucida Zona Pellucida - physiology Green Fluorescent Proteins Cell Line Teratoma Genes Blastocyst Reporter Macaca mulatta Alkaline Phosphatase Reverse Transcriptase Polymerase Chain Reaction Lentivirus tau Proteins Stem Cell Transplantation Animals Zona Pellucida Transfection Cell Differentiation Embryonic Stem Cells
Online Access	Get full text

Cover

Loading…

Abstract	Embryonic stem cells (ESC) have the ability of indefinite self‐renewal and multilineage differentiation, and they carry great potential in cell‐based therapies. The rhesus macaque is the most relevant preclinical model for assessing the benefit, safety, and efficacy of ESC‐based transplantations in the treatment of neurodegenerative diseases. In the case of neural cell grafting, tracing both the neurons and their axonal projections in vivo is essential for studying the integration of the grafted cells in the host brain. Tau‐Green fluorescent protein (tau‐GFP) is a powerful viable lineage tracer, allowing visualization of cell bodies, dendrites, and axons in exquisite detail. Here, we report the first rhesus monkey ESC line that ubiquitously and stably expresses tau‐GFP. First, we derived a new line of rhesus monkey ESC (LYON‐ES1) that show marker expression and cell cycle characteristics typical of primate ESCs. LYON‐ES1 cells are pluripotent, giving rise to derivatives of the three germ layers in vitro and in vivo through teratoma formation. They retain all their undifferentiated characteristics and a normal karyotype after prolonged culture. Using lentiviral infection, we then generated a monkey ESC line stably expressing tau‐GFP that retains all the characteristics of the parental wild‐type line and is clonogenic. We show that neural precursors derived from the tau‐GFP ESC line are multipotent and that their fate can be precisely mapped in vivo after grafting in the adult rat brain. Disclosure of potential conflicts of interest is found at the end of this article.
AbstractList	Embryonic stem cells (ESC) have the ability of indefinite self-renewal and multilineage differentiation, and carry great potential in cell based therapies. The rhesus macaque is the most relevant preclinical model for assessing the benefit, safety and efficacy of ESC based transplantations in the treatment of neurodegenerative diseases. In the case of neural cell grafting, tracing both the neurons and their axonal projections in vivo is essential for studying the integration of the grafted cells in the host brain. Tau-green fluorescent protein (tau-GFP) is a powerful viable lineage tracer, allowing to visualize cell bodies, dendrites and axons in exquisite details. Here, we report the first rhesus monkey ESC line that ubiquituously and stably expresses tau-GFP. First, we derived a new line of rhesus monkey ESC (LYON-ES1), that show marker expression and cell cycle characteristics typical of primate ES cells. LYON-ES1 cells are pluripotent, giving rise to derivatives of the three germ layers in vitro and in vivo through teratoma formation. They retain all their undifferentiated characteristics and a normal karyotype after prolonged culture. Using lentiviral infection, we then generated a monkey ES cell line stably expressing tau-GFP that retains all the characteristics of the parental wild type line and is clonogenic. We show that neural precursors derived from the tau-GFP ESC line are multipotent and that their fate can precisely be mapped in vivo after grafting in the adult rat brain. Embryonic stem cells (ESC) have the ability of indefinite self-renewal and multilineage differentiation, and they carry great potential in cell-based therapies. The rhesus macaque is the most relevant preclinical model for assessing the benefit, safety, and efficacy of ESC-based transplantations in the treatment of neurodegenerative diseases. In the case of neural cell grafting, tracing both the neurons and their axonal projections in vivo is essential for studying the integration of the grafted cells in the host brain. Tau-Green fluorescent protein (tau-GFP) is a powerful viable lineage tracer, allowing visualization of cell bodies, dendrites, and axons in exquisite detail. Here, we report the first rhesus monkey ESC line that ubiquitously and stably expresses tau-GFP. First, we derived a new line of rhesus monkey ESC (LYON-ES1) that show marker expression and cell cycle characteristics typical of primate ESCs. LYON-ES1 cells are pluripotent, giving rise to derivatives of the three germ layers in vitro and in vivo through teratoma formation. They retain all their undifferentiated characteristics and a normal karyotype after prolonged culture. Using lentiviral infection, we then generated a monkey ESC line stably expressing tau-GFP that retains all the characteristics of the parental wild-type line and is clonogenic. We show that neural precursors derived from the tau-GFP ESC line are multipotent and that their fate can be precisely mapped in vivo after grafting in the adult rat brain. Disclosure of potential conflicts of interest is found at the end of this article. Abstract Embryonic stem cells (ESC) have the ability of indefinite self-renewal and multilineage differentiation, and they carry great potential in cell-based therapies. The rhesus macaque is the most relevant preclinical model for assessing the benefit, safety, and efficacy of ESC-based transplantations in the treatment of neurodegenerative diseases. In the case of neural cell grafting, tracing both the neurons and their axonal projections in vivo is essential for studying the integration of the grafted cells in the host brain. Tau-Green fluorescent protein (tau-GFP) is a powerful viable lineage tracer, allowing visualization of cell bodies, dendrites, and axons in exquisite detail. Here, we report the first rhesus monkey ESC line that ubiquitously and stably expresses tau-GFP. First, we derived a new line of rhesus monkey ESC (LYON-ES1) that show marker expression and cell cycle characteristics typical of primate ESCs. LYON-ES1 cells are pluripotent, giving rise to derivatives of the three germ layers in vitro and in vivo through teratoma formation. They retain all their undifferentiated characteristics and a normal karyotype after prolonged culture. Using lentiviral infection, we then generated a monkey ESC line stably expressing tau-GFP that retains all the characteristics of the parental wild-type line and is clonogenic. We show that neural precursors derived from the tau-GFP ESC line are multipotent and that their fate can be precisely mapped in vivo after grafting in the adult rat brain. Disclosure of potential conflicts of interest is found at the end of this article. Embryonic stem cells (ESC) have the ability of indefinite self‐renewal and multilineage differentiation, and they carry great potential in cell‐based therapies. The rhesus macaque is the most relevant preclinical model for assessing the benefit, safety, and efficacy of ESC‐based transplantations in the treatment of neurodegenerative diseases. In the case of neural cell grafting, tracing both the neurons and their axonal projections in vivo is essential for studying the integration of the grafted cells in the host brain. Tau‐Green fluorescent protein (tau‐GFP) is a powerful viable lineage tracer, allowing visualization of cell bodies, dendrites, and axons in exquisite detail. Here, we report the first rhesus monkey ESC line that ubiquitously and stably expresses tau‐GFP. First, we derived a new line of rhesus monkey ESC (LYON‐ES1) that show marker expression and cell cycle characteristics typical of primate ESCs. LYON‐ES1 cells are pluripotent, giving rise to derivatives of the three germ layers in vitro and in vivo through teratoma formation. They retain all their undifferentiated characteristics and a normal karyotype after prolonged culture. Using lentiviral infection, we then generated a monkey ESC line stably expressing tau‐GFP that retains all the characteristics of the parental wild‐type line and is clonogenic. We show that neural precursors derived from the tau‐GFP ESC line are multipotent and that their fate can be precisely mapped in vivo after grafting in the adult rat brain. Disclosure of potential conflicts of interest is found at the end of this article.
Author	Markossian, Suzy Wianny, Florence Dehay, Colette Bernat, Agnieszka Kennedy, Henry Leviel, Vincent Marcy, Guillaume Savatier, Pierre Giroud, Pascale Huissoud, Cyril Cortay, Véronique
AuthorAffiliation	2 Service de Gynécologie et Obstétrique Hospices civils de Lyon Hôpital de la Croix Rousse 69004 Lyon,FR 3 Unité sous contrat plate-forme biotechnologique de cellules souches plate-forme PrimaStem INRA INSERM Université Claude Bernard - Lyon I 69500 Bron,FR 1 Institut cellule souche et cerveau INSERM : U846 Université Claude Bernard - Lyon I Centre de recherche Inserm 18, avenue du doyen lepine 69676 BRON CEDEX,FR
AuthorAffiliation_xml	– name: 3 Unité sous contrat plate-forme biotechnologique de cellules souches plate-forme PrimaStem INRA INSERM Université Claude Bernard - Lyon I 69500 Bron,FR – name: 1 Institut cellule souche et cerveau INSERM : U846 Université Claude Bernard - Lyon I Centre de recherche Inserm 18, avenue du doyen lepine 69676 BRON CEDEX,FR – name: 2 Service de Gynécologie et Obstétrique Hospices civils de Lyon Hôpital de la Croix Rousse 69004 Lyon,FR
Author_xml	– sequence: 1 givenname: Florence surname: Wianny fullname: Wianny, Florence – sequence: 2 givenname: Agnieszka surname: Bernat fullname: Bernat, Agnieszka – sequence: 3 givenname: Cyril surname: Huissoud fullname: Huissoud, Cyril – sequence: 4 givenname: Guillaume surname: Marcy fullname: Marcy, Guillaume – sequence: 5 givenname: Suzy surname: Markossian fullname: Markossian, Suzy – sequence: 6 givenname: Véronique surname: Cortay fullname: Cortay, Véronique – sequence: 7 givenname: Pascale surname: Giroud fullname: Giroud, Pascale – sequence: 8 givenname: Vincent surname: Leviel fullname: Leviel, Vincent – sequence: 9 givenname: Henry surname: Kennedy fullname: Kennedy, Henry – sequence: 10 givenname: Pierre surname: Savatier fullname: Savatier, Pierre – sequence: 11 givenname: Colette surname: Dehay fullname: Dehay, Colette email: Colette.Dehay@inserm.fr
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/18356572$$D View this record in MEDLINE/PubMed https://inserm.hal.science/inserm-00409448$$DView record in HAL
BookMark	eNqNkclu1DAYxy1URBd4AiTkEydS7NhObCEhVcO0RRoW0eFsOZ4vHaPEntrJwNx4BJ6RJ8HRjMpy4uTl-y-2fqfoyAcPCD2l5JxWjL9MA_QWui6dl4TUBVGCPUAnVHBVcEXlUd6TqioEUeoYnab0hRDKhZSP0DGVTFSiLk9QegPRbc3ggsfGr_CsC975WxxabPD7sIUOf1pDGhOe903c5aHFN7kYz3IzXjgP-Wiabofn3zYRUprMSzP-_P7jKgJ4fNmNId9b8AP-GMMAzj9GD1vTJXhyWM_Q58v5cnZdLD5cvZ1dLAorSsYLRmpbMZBUlaUEroziJRAmG9FCs5KybVcVBWZboEzJyvJa1DWHitCmVQ217Ay93uduxqaH1fSEaDq9ia43caeDcfrviXdrfRu2uqw5kZzkgBf7gPU_tuuLhXY-Qew1IZwozuWWZvnzQ18MdyOkQfcuTYSMhzAmTZVUUkiWhWwvtDGkFKG9D6dET2z1PVs9sdUT2-x69ud3fnsOMLPg1V7w1XWw-59MfbOcvysryjlnvwDOKrnR
CitedBy_id	crossref_primary_10_1038_ncomms8095 crossref_primary_10_1101_pdb_top85 crossref_primary_10_1016_j_scr_2012_10_004 crossref_primary_10_1016_j_scr_2017_01_008 crossref_primary_10_1073_pnas_1006563107 crossref_primary_10_1016_j_bbrc_2022_06_077 crossref_primary_10_1016_j_ymthe_2016_10_007 crossref_primary_10_1002_stem_110 crossref_primary_10_1007_s13577_014_0088_9 crossref_primary_10_3390_ijms25031642 crossref_primary_10_1089_scd_2010_0224 crossref_primary_10_1242_bio_20134242 crossref_primary_10_1002_jbm_b_33778 crossref_primary_10_1016_j_celrep_2016_06_066 crossref_primary_10_1021_acs_biomac_0c00825 crossref_primary_10_3727_096368912X658764 crossref_primary_10_1002_advs_202103827 crossref_primary_10_1016_j_stemcr_2023_09_013 crossref_primary_10_1016_j_yexcr_2019_111712 crossref_primary_10_1021_acs_biomac_6b00820 crossref_primary_10_1016_j_scr_2016_03_002 crossref_primary_10_1080_15384101_2018_1464848 crossref_primary_10_1016_j_scr_2017_09_001 crossref_primary_10_3724_SP_J_1141_2012_01043 crossref_primary_10_1016_j_stemcr_2020_12_004 crossref_primary_10_2139_ssrn_3155622 crossref_primary_10_1016_j_diff_2011_01_008 crossref_primary_10_3727_096368910X504469 crossref_primary_10_1016_j_stemcr_2018_09_005 crossref_primary_10_1089_scd_2017_0053 crossref_primary_10_1038_cr_2016_156 crossref_primary_10_1155_2016_1568145 crossref_primary_10_1038_ncomms4719 crossref_primary_10_1016_j_scr_2009_02_004 crossref_primary_10_1016_j_neuroscience_2017_03_004
Cites_doi	10.1073/pnas.032662199 10.1089/scd.2004.13.421 10.1186/1477-7827-2-41 10.1095/biolreprod55.2.254 10.1634/stemcells.2004-0172 10.1002/jcp.20776 10.1172/JCI21137 10.1111/j.1460-9568.2006.05093.x 10.3748/wjg.v12.i42.6818 10.1095/biolreprod.102.012195 10.3727/000000002783985350 10.1073/pnas.2034195100 10.1006/dbio.2000.9912 10.1083/jcb.143.3.777 10.1634/stemcells.21-3-281 10.1016/S0006-291X(03)00937-9 10.1083/jcb.101.4.1371 10.1634/stemcells.2006-0125 10.1263/jbb.102.14 10.1038/sj.jcbfm.9600247 10.1089/scd.2006.15.200 10.1016/S0092-8674(00)80730-8 10.1634/stemcells.2007-0073 10.1016/S0166-2236(99)01428-9 10.1089/clo.2006.8.225 10.1089/scd.2006.15.61 10.1006/mthe.2002.0655 10.1016/j.nbd.2005.01.031 10.1002/dvdy.1191 10.1006/dbio.2000.9935 10.1634/stemcells.2006-0225 10.1182/blood-2006-06-031039 10.1089/clo.2006.8.16 10.1186/1477-7827-2-42 10.1634/stemcells.2005-0194 10.1073/pnas.92.17.7844 10.1007/978-1-59745-154-3_10 10.1634/stemcells.2007-0286 10.1111/j.1699-0463.1998.tb01330.x
ContentType	Journal Article
Copyright	Copyright © 2008 AlphaMed Press Distributed under a Creative Commons Attribution 4.0 International License
Copyright_xml	– notice: Copyright © 2008 AlphaMed Press – notice: Distributed under a Creative Commons Attribution 4.0 International License
DBID	CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QO 7TK 7U9 8FD FR3 H94 P64 RC3 1XC VOOES 5PM
DOI	10.1634/stemcells.2007-0953
DatabaseName	Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Biotechnology Research Abstracts Neurosciences Abstracts Virology and AIDS Abstracts Technology Research Database Engineering Research Database AIDS and Cancer Research Abstracts Biotechnology and BioEngineering Abstracts Genetics Abstracts Hyper Article en Ligne (HAL) Hyper Article en Ligne (HAL) (Open Access) PubMed Central (Full Participant titles)
DatabaseTitle	MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Genetics Abstracts Virology and AIDS Abstracts Biotechnology Research Abstracts Technology Research Database AIDS and Cancer Research Abstracts Engineering Research Database Neurosciences Abstracts Biotechnology and BioEngineering Abstracts
DatabaseTitleList	Genetics Abstracts CrossRef MEDLINE
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Biology
DocumentTitleAlternate	A novel Rhesus ES cell line stably expressing tau-GFP
EISSN	1549-4918
EndPage	1453
ExternalDocumentID	oai_HAL_inserm_00409448v1 10_1634_stemcells_2007_0953 18356572 STEM261444
Genre	article Research Support, Non-U.S. Gov't Journal Article
GroupedDBID	--- .GJ 05W 0R~ 123 18M 1OB 1OC 24P 2WC 31~ 3WU 4.4 53G 5RE 5WD 8-0 8-1 A00 AABZA AACZT AAESR AAIHA AAONW AAPGJ AAPXW AARHZ AASNB AAUAY AAVAP AAWDT AAZKR ABCUV ABHFT ABLJU ABMNT ABNHQ ABPTD ABXVV ACFRR ACGFO ACGFS ACIWK ACPOU ACPRK ACUFI ACUTJ ACXQS ACZBC ADBBV ADGKP ADIPN ADKYN ADQBN ADVEK ADXAS ADZMN AENEX AEUQT AFBPY AFFZL AFGWE AFRAH AFYAG AFZJQ AGMDO AHMBA AIURR AJAOE AJEEA ALMA_UNASSIGNED_HOLDINGS AMYDB APJGH ATGXG AVNTJ AZBYB AZVAB BAWUL BCRHZ BEYMZ BMXJE BRXPI CS3 DCZOG DIK DU5 E3Z EBS EJD EMB EMOBN F5P FD6 G-S GODZA GX1 H13 HHY HZ~ IH2 KOP KSI KSN LATKE LEEKS LH4 LITHE LMP LOXES LUTES LW6 LYRES MY~ N9A NNB NOMLY O66 O9- OBOKY OCZFY OIG OJZSN OK1 OPAEJ OVD OWPYF P2P P2W P4E PALCI PQQKQ RAO RIWAO RJQFR ROL ROX RWI SUPJJ SV3 TEORI TMA TR2 WBKPD WOHZO WOQ WYB WYJ XV2 ZGI ZXP ZZTAW ~S- CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QO 7TK 7U9 8FD FR3 H94 P64 RC3 1XC VOOES 5PM
ID	FETCH-LOGICAL-c5234-307c63e819228e49a942e038b5febd88ffd61e3cfe13986c475774e601bf9b1c3
ISSN	1066-5099 1066-6099
IngestDate	Tue Sep 17 21:13:14 EDT 2024 Tue Oct 15 15:36:10 EDT 2024 Fri Oct 25 01:53:35 EDT 2024 Fri Aug 23 03:25:27 EDT 2024 Tue Oct 15 23:31:32 EDT 2024 Sat Aug 24 00:39:58 EDT 2024
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	6
Keywords	Green Fluorescent Proteins Cell Line Teratoma Genes Blastocyst Reporter Macaca mulatta Alkaline Phosphatase Reverse Transcriptase Polymerase Chain Reaction Lentivirus tau Proteins Stem Cell Transplantation Animals Zona Pellucida Transfection Cell Differentiation Embryonic Stem Cells
Language	English
License	Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
LinkModel	OpenURL
MergedId	FETCHMERGED-LOGICAL-c5234-307c63e819228e49a942e038b5febd88ffd61e3cfe13986c475774e601bf9b1c3
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Agnieszka Bernat: data collection Pascale Giroud: data collection Cyril Huissoud: data collection Colette Dehay: conception and design, data assembly and interpretation, financial support, manuscript writing Guillaume Marcy: data collection and analysis Suzy Markossian: provision of lentiviral vectors Véronique Cortay: data collection Pierre Savatier: conception and design, data interpretation, financial support, help with writing Vincent Leviel: data collection Florence Wianny: conception and design, data collection and interpretation, manuscript writing Henry Kennedy : financial and administrative support, help with writing
ORCID	0000-0003-3545-569X
OpenAccessLink	https://inserm.hal.science/inserm-00409448
PMID	18356572
PQID	19898583
PQPubID	23462
PageCount	10
ParticipantIDs	pubmedcentral_primary_oai_pubmedcentral_nih_gov_2740840 hal_primary_oai_HAL_inserm_00409448v1 proquest_miscellaneous_19898583 crossref_primary_10_1634_stemcells_2007_0953 pubmed_primary_18356572 wiley_primary_10_1634_stemcells_2007_0953_STEM261444
PublicationCentury	2000
PublicationDate	June 2008
PublicationDateYYYYMMDD	2008-06-01
PublicationDate_xml	– month: 06 year: 2008 text: June 2008
PublicationDecade	2000
PublicationPlace	Bristol
PublicationPlace_xml	– name: Bristol – name: United States
PublicationTitle	Stem cells (Dayton, Ohio)
PublicationTitleAlternate	Stem Cells
PublicationYear	2008
Publisher	John Wiley & Sons, Ltd Alphamed Press AlphaMed Press
Publisher_xml	– name: John Wiley & Sons, Ltd – name: Alphamed Press – name: AlphaMed Press
References	2001; 222 1995; 92 2006; 12 2005; 115 2002; 6 2002; 99 2006; 15 2002; 11 1985; 101 2006; 8 1999; 22 2005; 20 2004; 2 2007; 109 2005; 23 2006; 331 1996; 55 2003; 306 2006; 209 2006; 24 2000; 227 2000; 228 2006; 26 2004; 13 2003; 68 1999; 97 1998; 106 1998; 143 2006; 348 2003; 100 2007; 25 2003; 21 2006; 102 16137565 - Neurobiol Dis. 2005 Oct;20(1):38-48 16881509 - Methods Mol Biol. 2006;331:55-76 14504386 - Proc Natl Acad Sci U S A. 2003 Sep 30;100 Suppl 1:11911-6 16646666 - Stem Cells Dev. 2006 Apr;15(2):200-8 16571074 - Cloning Stem Cells. 2006;8(1):16-23 7544005 - Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7844-8 17090646 - Blood. 2007 Mar 15;109(6):2406-15 16522163 - Stem Cells Dev. 2006 Feb;15(1):61-9 16741224 - Stem Cells. 2006 Oct;24(10):2177-86 15200688 - Reprod Biol Endocrinol. 2004 Jun 16;2:41 12743323 - Stem Cells. 2003;21(3):281-95 11818560 - Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1580-5 8828827 - Biol Reprod. 1996 Aug;55(2):254-9 16972248 - J Cell Physiol. 2006 Dec;209(3):883-93 11087623 - Dev Biol. 2000 Dec 1;228(1):19-28 17138962 - Stem Cells. 2007 Mar;25(3):571-80 17641389 - Stem Cells. 2007 Nov;25(11):2695-704 11071754 - Dev Biol. 2000 Nov 15;227(2):271-8 15941857 - Stem Cells. 2005 Aug;23(7):914-22 9813097 - J Cell Biol. 1998 Nov 2;143(3):777-94 9524573 - APMIS. 1998 Jan;106(1):149-56; discussion 156-7 12518890 - Cell Transplant. 2002;11(7):631-5 10407421 - Trends Neurosci. 1999 Aug;22(8):357-64 17009898 - Cloning Stem Cells. 2006 Fall;8(3):225-34 16395293 - J Cereb Blood Flow Metab. 2006 Jul;26(7):906-14 17067292 - Eur J Neurosci. 2006 Oct;24(7):1885-96 15345136 - Stem Cells Dev. 2004 Aug;13(4):421-35 12788087 - Biochem Biophys Res Commun. 2003 Jun 20;306(1):191-7 16952831 - J Biosci Bioeng. 2006 Jul;102(1):14-20 12161182 - Mol Ther. 2002 Aug;6(2):162-8 15200687 - Reprod Biol Endocrinol. 2004 Jun 16;2:42 12606331 - Biol Reprod. 2003 May;68(5):1727-35 16239321 - Stem Cells. 2006 Mar;24(3):547-56 17464084 - Stem Cells. 2007 Aug;25(8):1924-30 11668604 - Dev Dyn. 2001 Oct;222(2):273-9 10219241 - Cell. 1999 Apr 16;97(2):199-208 3930508 - J Cell Biol. 1985 Oct;101(4):1371-8 15630449 - J Clin Invest. 2005 Jan;115(1):102-9 16988378 - Methods Mol Biol. 2006;348:151-68 17106931 - World J Gastroenterol. 2006 Nov 14;12(42):6818-27 Blum (2022011314443209300_bib33) 2007; 25 Sidhu (2022011314443209300_bib35) 2006; 15 Navara (2022011314443209300_bib8) 2007; 25 Thomson (2022011314443209300_bib13) 1998; 106 Forsyth (2022011314443209300_bib27) 2006; 8 Suemori (2022011314443209300_bib4) 2001; 222 Kuo (2022011314443209300_bib17) 2003; 68 Kawasaki (2022011314443209300_bib16) 2002; 99 Tibbitts (2022011314443209300_bib18) 2006; 15 Mitalipov (2022011314443209300_bib7) 2006; 348 Lester (2022011314443209300_bib11) 2004; 2 Becker (2022011314443209300_bib31) 2006; 209 Pau (2022011314443209300_bib6) 2004; 2 Takagi (2022011314443209300_bib20) 2005; 115 Chen (2022011314443209300_bib15) 2003; 21 Takada (2022011314443209300_bib36) 2002; 11 Hewitt (2022011314443209300_bib28) 2006; 8 Gertow (2022011314443209300_bib32) 2004; 13 Amit (2022011314443209300_bib34) 2000; 227 Asano (2022011314443209300_bib38) 2002; 6 Calhoun (2022011314443209300_bib14) 2003; 306 Mitalipova (2022011314443209300_bib29) 2006; 331 Thomson (2022011314443209300_bib2) 1995; 92 Mitalipov (2022011314443209300_bib30) 2006; 24 Fluckiger (2022011314443209300_bib26) 2006; 24 Ebneth (2022011314443209300_bib40) 1998; 143 Rodriguez (2022011314443209300_bib24) 1999; 97 Binder (2022011314443209300_bib39) 1985; 101 Vrana (2022011314443209300_bib5) 2003; 100 Svendsen (2022011314443209300_bib1) 1999; 22 Sánchez-Pernaute (2022011314443209300_bib21) 2005; 23 Pratt (2022011314443209300_bib25) 2000; 228 Shinoda (2022011314443209300_bib9) 2007; 109 Ferrari (2022011314443209300_bib22) 2006; 24 Hosseinkhani (2022011314443209300_bib12) 2007; 25 Hayashi (2022011314443209300_bib23) 2006; 26 Thomson (2022011314443209300_bib3) 1996; 55 Ueda (2022011314443209300_bib37) 2006; 102 Saito (2022011314443209300_bib10) 2006; 12 Ikeda (2022011314443209300_bib19) 2005; 20
References_xml	– volume: 15 start-page: 61 year: 2006 end-page: 69 article-title: Derivation of three clones from human embryonic stem cell lines by FACS sorting and their characterization publication-title: Stem Cells Dev – volume: 100 start-page: 11911 issue: Suppl 1 year: 2003 end-page: 11916 article-title: Nonhuman primate parthenogenetic stem cells publication-title: Proc Natl Acad Sci U S A – volume: 99 start-page: 1580 year: 2002 end-page: 1585 article-title: Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell‐derived inducing activity publication-title: Proc Natl Acad Sci U S A – volume: 8 start-page: 225 year: 2006 end-page: 234 article-title: Fluorescence‐activated single cell sorting of human embryonic stem cells publication-title: Cloning Stem Cells – volume: 25 start-page: 1924 year: 2007 end-page: 1930 article-title: Clonal analysis of human embryonic stem cell differentiation into teratomas publication-title: Stem Cells – volume: 11 start-page: 631 year: 2002 end-page: 635 article-title: Monkey embryonic stem cell lines expressing green fluorescent protein publication-title: Cell Transplant – volume: 24 start-page: 547 year: 2006 end-page: 556 article-title: Cell cycle features of primate embryonic stem cells publication-title: Stem Cells – volume: 8 start-page: 16 year: 2006 end-page: 23 article-title: Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities publication-title: Cloning Stem Cells – volume: 209 start-page: 883 year: 2006 end-page: 893 article-title: Self‐renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase publication-title: J Cell Physiol – volume: 25 start-page: 571 year: 2007 end-page: 580 article-title: Bone morphogenetic protein‐4 enhances cardiomyocyte differentiation of cynomolgus monkey ESCs in knockout serum replacement medium publication-title: Stem Cells – volume: 6 start-page: 162 year: 2002 end-page: 168 article-title: Highly efficient gene transfer into primate embryonic stem cells with a simian lentivirus vector publication-title: Mol Ther – volume: 12 start-page: 6818 year: 2006 end-page: 6827 article-title: Promoted differentiation of cynomolgus monkey ES cells into hepatocyte‐like cells by co‐culture with mouse fetal liver‐derived cells publication-title: World J Gastroenterol – volume: 109 start-page: 2406 year: 2007 end-page: 2415 article-title: alpha4‐Integrin(+) endothelium derived from primate embryonic stem cells generates primitive and definitive hematopoietic cells publication-title: Blood – volume: 68 start-page: 1727 year: 2003 end-page: 1735 article-title: Differentiation of monkey embryonic stem cells into neural lineages publication-title: Biol Reprod – volume: 22 start-page: 357 year: 1999 end-page: 364 article-title: New prospects for human stem‐cell therapy in the nervous system publication-title: Trends Neurosci – volume: 25 start-page: 2695 year: 2007 end-page: 2704 article-title: Pedigreed primate embryonic stem cells express homogeneous familial gene profiles publication-title: Stem Cells – volume: 24 start-page: 1885 year: 2006 end-page: 1896 article-title: Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP‐32 striatal progenitors within the graft publication-title: Eur J Neurosci – volume: 92 start-page: 7844 year: 1995 end-page: 7848 article-title: Isolation of a primate embryonic stem cell line publication-title: Proc Natl Acad Sci U S A – volume: 306 start-page: 191 year: 2003 end-page: 197 article-title: Differentiation of rhesus embryonic stem cells to neural progenitors and neurons publication-title: Biochem Biophys Res Commun – volume: 2 start-page: 41 year: 2004 article-title: Derivation and characterization of monkey embryonic stem cells publication-title: Reprod Biol Endocrinol – volume: 97 start-page: 199 year: 1999 end-page: 208 article-title: Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system publication-title: Cell – volume: 13 start-page: 421 year: 2004 end-page: 435 article-title: Organized development from human embryonic stem cells after injection into immunodeficient mice publication-title: Stem Cells Dev – volume: 106 start-page: 149 year: 1998 end-page: 156 article-title: Neural differentiation of rhesus embryonic stem cells publication-title: APMIS – volume: 115 start-page: 102 year: 2005 end-page: 109 article-title: Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model publication-title: J Clin Invest – volume: 101 start-page: 1371 year: 1985 end-page: 1378 article-title: The distribution of tau in the mammalian central nervous system publication-title: J Cell Biol – volume: 26 start-page: 906 year: 2006 end-page: 914 article-title: Primate embryonic stem cell‐derived neuronal progenitors transplanted into ischemic brain publication-title: J Cereb Blood Flow Metab – volume: 228 start-page: 19 year: 2000 end-page: 28 article-title: Embryonic stem cells and transgenic mice ubiquitously expressing a tau‐tagged green fluorescent protein publication-title: Dev Biol – volume: 348 start-page: 151 year: 2006 end-page: 168 article-title: Nuclear transfer in nonhuman primates publication-title: Methods Mol Biol – volume: 143 start-page: 777 year: 1998 end-page: 794 article-title: Overexpression of tau protein inhibits kinesin‐dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease publication-title: J Cell Biol – volume: 21 start-page: 281 year: 2003 end-page: 295 article-title: Multilineage differentiation of rhesus monkey embryonic stem cells in three‐dimensional culture systems publication-title: Stem Cells – volume: 55 start-page: 254 year: 1996 end-page: 259 article-title: Pluripotent cell lines derived from common marmoset ( ) blastocysts publication-title: Biol Reprod – volume: 23 start-page: 914 year: 2005 end-page: 922 article-title: Long‐term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno‐1) after transplantation publication-title: Stem Cells – volume: 331 start-page: 55 year: 2006 end-page: 76 article-title: Isolation and characterization of human embryonic stem cells publication-title: Methods Mol Biol – volume: 20 start-page: 38 year: 2005 end-page: 48 article-title: Transplantation of neural cells derived from retinoic acid‐treated cynomolgus monkey embryonic stem cells successfully improved motor function of hemiplegic mice with experimental brain injury publication-title: Neurobiol Dis – volume: 222 start-page: 273 year: 2001 end-page: 279 article-title: Establishment of embryonic stem cell lines from cynomolgus monkey blastocysts produced by IVF or ICSI publication-title: Dev Dyn – volume: 15 start-page: 200 year: 2006 end-page: 208 article-title: Uniform adherent neural progenitor populations from rhesus embryonic stem cells publication-title: Stem Cells Dev – volume: 102 start-page: 14 year: 2006 end-page: 20 article-title: Cynomolgus monkey embryonic stem cell lines express green fluorescent protein publication-title: J Biosci Bioeng – volume: 24 start-page: 2177 year: 2006 end-page: 2186 article-title: Isolation and characterization of novel rhesus monkey embryonic stem cell lines publication-title: Stem Cells – volume: 227 start-page: 271 year: 2000 end-page: 278 article-title: Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture publication-title: Dev Biol – volume: 2 start-page: 42 year: 2004 article-title: Directed differentiation of rhesus monkey ES cells into pancreatic cell phenotypes publication-title: Reprod Biol Endocrinol – volume: 99 start-page: 1580 year: 2002 ident: 2022011314443209300_bib16 article-title: Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.032662199 contributor: fullname: Kawasaki – volume: 13 start-page: 421 year: 2004 ident: 2022011314443209300_bib32 article-title: Organized development from human embryonic stem cells after injection into immunodeficient mice publication-title: Stem Cells Dev doi: 10.1089/scd.2004.13.421 contributor: fullname: Gertow – volume: 2 start-page: 41 year: 2004 ident: 2022011314443209300_bib6 article-title: Derivation and characterization of monkey embryonic stem cells publication-title: Reprod Biol Endocrinol doi: 10.1186/1477-7827-2-41 contributor: fullname: Pau – volume: 55 start-page: 254 year: 1996 ident: 2022011314443209300_bib3 article-title: Pluripotent cell lines derived from common marmoset (Callithrix jacchus) blastocysts publication-title: Biol Reprod doi: 10.1095/biolreprod55.2.254 contributor: fullname: Thomson – volume: 23 start-page: 914 year: 2005 ident: 2022011314443209300_bib21 article-title: Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation publication-title: Stem Cells doi: 10.1634/stemcells.2004-0172 contributor: fullname: Sánchez-Pernaute – volume: 209 start-page: 883 year: 2006 ident: 2022011314443209300_bib31 article-title: Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase publication-title: J Cell Physiol doi: 10.1002/jcp.20776 contributor: fullname: Becker – volume: 115 start-page: 102 year: 2005 ident: 2022011314443209300_bib20 article-title: Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model publication-title: J Clin Invest doi: 10.1172/JCI21137 contributor: fullname: Takagi – volume: 24 start-page: 1885 year: 2006 ident: 2022011314443209300_bib22 article-title: Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft publication-title: Eur J Neurosci doi: 10.1111/j.1460-9568.2006.05093.x contributor: fullname: Ferrari – volume: 12 start-page: 6818 year: 2006 ident: 2022011314443209300_bib10 article-title: Promoted differentiation of cynomolgus monkey ES cells into hepatocyte-like cells by co-culture with mouse fetal liver-derived cells publication-title: World J Gastroenterol doi: 10.3748/wjg.v12.i42.6818 contributor: fullname: Saito – volume: 68 start-page: 1727 year: 2003 ident: 2022011314443209300_bib17 article-title: Differentiation of monkey embryonic stem cells into neural lineages publication-title: Biol Reprod doi: 10.1095/biolreprod.102.012195 contributor: fullname: Kuo – volume: 11 start-page: 631 year: 2002 ident: 2022011314443209300_bib36 article-title: Monkey embryonic stem cell lines expressing green fluorescent protein publication-title: Cell Transplant doi: 10.3727/000000002783985350 contributor: fullname: Takada – volume: 100 start-page: 11911 issue: Suppl 1 year: 2003 ident: 2022011314443209300_bib5 article-title: Nonhuman primate parthenogenetic stem cells publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.2034195100 contributor: fullname: Vrana – volume: 227 start-page: 271 year: 2000 ident: 2022011314443209300_bib34 article-title: Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture publication-title: Dev Biol doi: 10.1006/dbio.2000.9912 contributor: fullname: Amit – volume: 143 start-page: 777 year: 1998 ident: 2022011314443209300_bib40 article-title: Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease publication-title: J Cell Biol doi: 10.1083/jcb.143.3.777 contributor: fullname: Ebneth – volume: 21 start-page: 281 year: 2003 ident: 2022011314443209300_bib15 article-title: Multilineage differentiation of rhesus monkey embryonic stem cells in three-dimensional culture systems publication-title: Stem Cells doi: 10.1634/stemcells.21-3-281 contributor: fullname: Chen – volume: 306 start-page: 191 year: 2003 ident: 2022011314443209300_bib14 article-title: Differentiation of rhesus embryonic stem cells to neural progenitors and neurons publication-title: Biochem Biophys Res Commun doi: 10.1016/S0006-291X(03)00937-9 contributor: fullname: Calhoun – volume: 101 start-page: 1371 year: 1985 ident: 2022011314443209300_bib39 article-title: The distribution of tau in the mammalian central nervous system publication-title: J Cell Biol doi: 10.1083/jcb.101.4.1371 contributor: fullname: Binder – volume: 24 start-page: 2177 year: 2006 ident: 2022011314443209300_bib30 article-title: Isolation and characterization of novel rhesus monkey embryonic stem cell lines publication-title: Stem Cells doi: 10.1634/stemcells.2006-0125 contributor: fullname: Mitalipov – volume: 102 start-page: 14 year: 2006 ident: 2022011314443209300_bib37 article-title: Cynomolgus monkey embryonic stem cell lines express green fluorescent protein publication-title: J Biosci Bioeng doi: 10.1263/jbb.102.14 contributor: fullname: Ueda – volume: 26 start-page: 906 year: 2006 ident: 2022011314443209300_bib23 article-title: Primate embryonic stem cell-derived neuronal progenitors transplanted into ischemic brain publication-title: J Cereb Blood Flow Metab doi: 10.1038/sj.jcbfm.9600247 contributor: fullname: Hayashi – volume: 15 start-page: 200 year: 2006 ident: 2022011314443209300_bib18 article-title: Uniform adherent neural progenitor populations from rhesus embryonic stem cells publication-title: Stem Cells Dev doi: 10.1089/scd.2006.15.200 contributor: fullname: Tibbitts – volume: 97 start-page: 199 year: 1999 ident: 2022011314443209300_bib24 article-title: Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system publication-title: Cell doi: 10.1016/S0092-8674(00)80730-8 contributor: fullname: Rodriguez – volume: 25 start-page: 1924 year: 2007 ident: 2022011314443209300_bib33 article-title: Clonal analysis of human embryonic stem cell differentiation into teratomas publication-title: Stem Cells doi: 10.1634/stemcells.2007-0073 contributor: fullname: Blum – volume: 22 start-page: 357 year: 1999 ident: 2022011314443209300_bib1 article-title: New prospects for human stem-cell therapy in the nervous system publication-title: Trends Neurosci doi: 10.1016/S0166-2236(99)01428-9 contributor: fullname: Svendsen – volume: 8 start-page: 225 year: 2006 ident: 2022011314443209300_bib28 article-title: Fluorescence-activated single cell sorting of human embryonic stem cells publication-title: Cloning Stem Cells doi: 10.1089/clo.2006.8.225 contributor: fullname: Hewitt – volume: 15 start-page: 61 year: 2006 ident: 2022011314443209300_bib35 article-title: Derivation of three clones from human embryonic stem cell lines by FACS sorting and their characterization publication-title: Stem Cells Dev doi: 10.1089/scd.2006.15.61 contributor: fullname: Sidhu – volume: 6 start-page: 162 year: 2002 ident: 2022011314443209300_bib38 article-title: Highly efficient gene transfer into primate embryonic stem cells with a simian lentivirus vector publication-title: Mol Ther doi: 10.1006/mthe.2002.0655 contributor: fullname: Asano – volume: 20 start-page: 38 year: 2005 ident: 2022011314443209300_bib19 article-title: Transplantation of neural cells derived from retinoic acid-treated cynomolgus monkey embryonic stem cells successfully improved motor function of hemiplegic mice with experimental brain injury publication-title: Neurobiol Dis doi: 10.1016/j.nbd.2005.01.031 contributor: fullname: Ikeda – volume: 331 start-page: 55 year: 2006 ident: 2022011314443209300_bib29 article-title: Isolation and characterization of human embryonic stem cells publication-title: Methods Mol Biol contributor: fullname: Mitalipova – volume: 222 start-page: 273 year: 2001 ident: 2022011314443209300_bib4 article-title: Establishment of embryonic stem cell lines from cynomolgus monkey blastocysts produced by IVF or ICSI publication-title: Dev Dyn doi: 10.1002/dvdy.1191 contributor: fullname: Suemori – volume: 228 start-page: 19 year: 2000 ident: 2022011314443209300_bib25 article-title: Embryonic stem cells and transgenic mice ubiquitously expressing a tau-tagged green fluorescent protein publication-title: Dev Biol doi: 10.1006/dbio.2000.9935 contributor: fullname: Pratt – volume: 25 start-page: 571 year: 2007 ident: 2022011314443209300_bib12 article-title: Bone morphogenetic protein-4 enhances cardiomyocyte differentiation of cynomolgus monkey ESCs in knockout serum replacement medium publication-title: Stem Cells doi: 10.1634/stemcells.2006-0225 contributor: fullname: Hosseinkhani – volume: 109 start-page: 2406 year: 2007 ident: 2022011314443209300_bib9 article-title: alpha4-Integrin(+) endothelium derived from primate embryonic stem cells generates primitive and definitive hematopoietic cells publication-title: Blood doi: 10.1182/blood-2006-06-031039 contributor: fullname: Shinoda – volume: 8 start-page: 16 year: 2006 ident: 2022011314443209300_bib27 article-title: Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities publication-title: Cloning Stem Cells doi: 10.1089/clo.2006.8.16 contributor: fullname: Forsyth – volume: 2 start-page: 42 year: 2004 ident: 2022011314443209300_bib11 article-title: Directed differentiation of rhesus monkey ES cells into pancreatic cell phenotypes publication-title: Reprod Biol Endocrinol doi: 10.1186/1477-7827-2-42 contributor: fullname: Lester – volume: 24 start-page: 547 year: 2006 ident: 2022011314443209300_bib26 article-title: Cell cycle features of primate embryonic stem cells publication-title: Stem Cells doi: 10.1634/stemcells.2005-0194 contributor: fullname: Fluckiger – volume: 92 start-page: 7844 year: 1995 ident: 2022011314443209300_bib2 article-title: Isolation of a primate embryonic stem cell line publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.92.17.7844 contributor: fullname: Thomson – volume: 348 start-page: 151 year: 2006 ident: 2022011314443209300_bib7 article-title: Nuclear transfer in nonhuman primates publication-title: Methods Mol Biol doi: 10.1007/978-1-59745-154-3_10 contributor: fullname: Mitalipov – volume: 25 start-page: 2695 year: 2007 ident: 2022011314443209300_bib8 article-title: Pedigreed primate embryonic stem cells express homogeneous familial gene profiles publication-title: Stem Cells doi: 10.1634/stemcells.2007-0286 contributor: fullname: Navara – volume: 106 start-page: 149 year: 1998 ident: 2022011314443209300_bib13 article-title: Neural differentiation of rhesus embryonic stem cells publication-title: APMIS doi: 10.1111/j.1699-0463.1998.tb01330.x contributor: fullname: Thomson
SSID	ssj0014588 ssib005900054
Score	2.1458166
Snippet	Embryonic stem cells (ESC) have the ability of indefinite self‐renewal and multilineage differentiation, and they carry great potential in cell‐based... Embryonic stem cells (ESC) have the ability of indefinite self-renewal and multilineage differentiation, and they carry great potential in cell-based... Abstract Embryonic stem cells (ESC) have the ability of indefinite self-renewal and multilineage differentiation, and they carry great potential in cell-based... Embryonic stem cells (ESC) have the ability of indefinite self-renewal and multilineage differentiation, and carry great potential in cell based therapies. The...
SourceID	pubmedcentral hal proquest crossref pubmed wiley
SourceType	Open Access Repository Aggregation Database Index Database Publisher
StartPage	1444
SubjectTerms	Alkaline Phosphatase Alkaline Phosphatase - metabolism Animals Blastocyst Blastocyst - cytology Cell Differentiation Cell Line Cellular Biology Embryonic Stem Cells Embryonic Stem Cells - cytology Embryonic Stem Cells - enzymology Embryonic Stem Cells - physiology Embryonic Stem Cells - virology Genes, Reporter Green fluorescent protein Green Fluorescent Proteins Green Fluorescent Proteins - genetics Lentivirus Life Sciences Macaca mulatta Primates Reverse Transcriptase Polymerase Chain Reaction Rhesus monkey Stem Cell Transplantation Stem Cell Transplantation - methods tau Proteins tau Proteins - genetics Teratoma Teratoma - genetics Teratoma - pathology Transfection Zona Pellucida Zona Pellucida - physiology
Title	Derivation and Cloning of a Novel Rhesus Embryonic Stem Cell Line Stably Expressing Tau‐Green Fluorescent Protein
URI	https://onlinelibrary.wiley.com/doi/abs/10.1634%2Fstemcells.2007-0953 https://www.ncbi.nlm.nih.gov/pubmed/18356572 https://search.proquest.com/docview/19898583 https://inserm.hal.science/inserm-00409448 https://pubmed.ncbi.nlm.nih.gov/PMC2740840
Volume	26
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb5tAEF45qSr1UvUd97mH9kRJbViW5RjlUauq20Mc1TcEyxJbtSG1TSTnL_RPd2Z3DVhxpbQXZIG1C3wfw8ww8y0h73OVQnAcSjcQkrksibib-j3lBlLkmae9VOxGHn7jgwv2ZRyMO53fraqlapUeypudfSX_gyrsA1yxS_YfkK0HhR3wG_CFLSAM2zthfAKTmJSqaU-bmdyqbnksyms1cxYTtayWjpqni7Ve6wZ1mx3M1jvavwTfMJ2tUedf18Ni61RSuZdYjOPks6pcGLUnR8s5WJFu68qeb0bSeduTZG0L8b9PpmUrv_AD-FdoJM9mpW4trDMAOhWpjdNlAQH7zc-kIRnwoaw0-47Xi6YMZAjPpemtqXC5pMpKLWzSFqIprzpU1tQyXN_OWl9ri033vOVc27BC3Md2WnzuM8QWLllf8aHJvUZGgbjFgau5JgFYMPzQ6zWvv7oocXNoj9zzwGqhufw8ruuF-tjSa2WrYM5PO2ZEAVo7xpaXszfBGtvbAcztOtx2fKQdnNEj8tBGJvTI0Owx6ajiCblv1ipdPyW_GrJRIBu1ZKNlThOqyUYN2WhNNopnT_H0KZKNGrLRhmy0JhttkY1asj0jF2eno-OBa9frcGXg-fiBLZTcVyix5wnFoiRinur5Ig3AImRC5HnG-8qXuYKwQ3DJwgCCD8V7_TSP0r70n5P9oizUAaGRl8mAh5nPmGTK40mWSp4lwud5gu3TXfJxc3_jKyPLEmM4C8jENTK4xGoYIzJd8gEwqP-JkuqDo6_xtABjMI_xRRYxJq77XfJug1IMZhZHSQpVVssYSwtFIGCkFwazZloLeZeEW2huzbZ9pJhOtJC7F7KeYL0uYRr3u1xJfD46HXqYxWEv_3oqr8iD5pF7TfZXi0q9Ad95lb7VnP4DKbjKTQ
link.rule.ids	230,315,783,787,888,27936,27937
linkProvider	Geneva Foundation for Medical Education and Research
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Derivation+and+cloning+of+a+novel+rhesus+embryonic+stem+cell+line+stably+expressing+tau-green+fluorescent+protein&rft.jtitle=Stem+cells+%28Dayton%2C+Ohio%29&rft.au=Wianny%2C+Florence&rft.au=Bernat%2C+Agnieszka&rft.au=Huissoud%2C+Cyril&rft.au=Marcy%2C+Guillaume&rft.date=2008-06-01&rft.eissn=1549-4918&rft.volume=26&rft.issue=6&rft.spage=1444&rft_id=info:doi/10.1634%2Fstemcells.2007-0953&rft_id=info%3Apmid%2F18356572&rft.externalDocID=18356572
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1066-5099&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1066-5099&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1066-5099&client=summon