The Parsortix™ Cell Separation System—A versatile liquid biopsy platform

• Published in: Cytometry. Part A Vol. 93; no. 12; pp. 1234 - 1239
• Main Authors: Miller, M. Craig, Robinson, Peggy S., Wagner, Christopher, O'Shannessy, Daniel J.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.12.2018; Wiley Subscription Services, Inc
• Subjects: Biopsy; Cancer; Cell Count - methods; Cell Line, Tumor; Cell Separation - methods; Cell Size; circulating tumor cell; Circulatory system; CTC Technologies and Tools; Cytometry; Deformability; Deformation; Formability; Humans; Interrogation; liquid biopsy; Liquid Biopsy - methods; MCF-7 Cells; Metastases; Microfluidics; Microfluidics - methods; Neoplastic Cells, Circulating - pathology; New technology; Preservatives; rare cell isolation; Separation; Solid tumors; Tumor cells; Tumors; Viability; circulating tumor cell; rare cell isolation; microfluidics; liquid biopsy

Cancer cells from solid tumors can enter the circulatory system and survive to subsequently form distant metastases. The CellSearch® system (Menarini‐Silicon Biosystems, Huntingdon Valley, PA) was the first, FDA‐cleared system that provided a reliable tool for the investigation of circulating tumor...