Colorimetric detection of kanamycin based on analyte-protected silver nanoparticles and aptamer-selective sensing mechanism

• Published in: Analytica chimica acta Vol. 891; pp. 298 - 303
• Main Authors: Xu, Yuanyuan, Han, Tian, Li, Xiaqing, Sun, Linghao, Zhang, Yujuan, Zhang, Yuanshu
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 03.09.2015
• Subjects: Analyte-protected silver nanoparticles; analytical chemistry; Animals; Anti-Bacterial Agents - analysis; Aptamer-selective; Aptamers, Nucleotide - chemistry; Cattle; Colorimetric; colorimetry; Colorimetry - methods; detection limit; Kanamycin; Kanamycin - analysis; Limit of Detection; maximum residue limits; Metal Nanoparticles - chemistry; Metal Nanoparticles - ultrastructure; milk; Milk - chemistry; nanosilver; nucleic acids; oligonucleotides; risk; Silver - chemistry; Analyte-protected silver nanoparticles; Kanamycin; Aptamer-selective; Colorimetric

In this work, a novel colorimetric detection method for kanamycin (Kana), a widely used aminoglycoside antibiotic, has been developed using unmodified silver nanoparticles (AgNPs) as sensing probe. The method is designed based on the finding that the analyte (Kana) can protect AgNPs against salt-ind...