Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies

• Published in: PloS one Vol. 13; no. 4; p. e0195659
• Main Authors: Liu, Xuling, Yu, Yang, Zhu, Shengmei
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 11.04.2018; Public Library of Science (PLoS)
• Subjects: Alzheimer's disease; Alzheimers disease; Anesthesia; Anesthesiology; Bioindicators; Biology and Life Sciences; Biomarkers; Biomarkers - metabolism; C-reactive protein; Cerebrospinal fluid; Clinical trials; Cognitive ability; Cognitive Dysfunction - metabolism; Cognitive Dysfunction - physiopathology; Confidence intervals; Cytokines; Data processing; Delirium; Delirium - metabolism; Delirium - physiopathology; Heart surgery; Heterogeneity; Humans; Inflammation; Inflammation - metabolism; Interleukin; Interleukin 6; Medicine; Medicine and Health Sciences; Mental disorders; Meta-analysis; Model testing; NMR; Nuclear magnetic resonance; Observational studies; Observational Studies as Topic; Patients; Peptides; Physical Sciences; Postoperative Complications - metabolism; Postoperative Complications - physiopathology; Quality; Regression analysis; Research and Analysis Methods; Sensitivity analysis; Social Sciences; Statistical analysis; Studies; Surgery; Systematic review; China

The aim of this study was to summarize and discuss the similarities and differences in inflammatory biomarkers in postoperative delirium (POD) and cognitive dysfunction (POCD). A systematic retrieval of literature up to June 2017 in PubMed, Embase, the Cochrane Library, the China National Knowledge...