Preoperative Radiotherapy Leads to Significant Differences in the Plasma Protein Profile of Rectal Cancer Patients

• Published in: Oncology Vol. 98; no. 7; pp. 493 - 500
• Main Authors: Holm, Matilda, Joenväärä, Sakari, Saraswat, Mayank, Tohmola, Tiialotta, Ristimäki, Ari, Renkonen, Risto, Haglund, Caj
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland 01.07.2020
• Subjects: Clinical Translational Research; Preoperative radiotherapy; Plasma; Mass spectrometry; Colorectal cancer; Proteomics

Introduction: Colorectal cancer (CRC) is the third most common cancer worldwide, accounting for 10% of the global cancer burden. Rectal cancer accounts for around 30% of CRC cases, and patients with resectable rectal cancer are often given preoperative radiotherapy (PRT) to reduce the rate of local...