Post-transcriptional gene regulation: From genome-wide studies to principles

• Published in: Cellular and molecular life sciences : CMLS Vol. 65; no. 5; pp. 798 - 813
• Main Authors: Halbeisen, R. E, Galgano, A, Scherrer, T, Gerber, A. P
• Format: Journal Article
• Language: English
• Published: Basel Basel : SP Birkhäuser Verlag Basel 01.03.2008; Birkhäuser-Verlag; Springer Nature B.V
• Subjects: Binding sites; Biochemistry; Biomedical and Life Sciences; Biomedicine; Cell Biology; DNA microarray; Gene expression; Gene Expression Regulation - physiology; Genome, Human; Humans; Life Sciences; Molecular biology; Physiology; Post-transcriptional gene regulation; Regulatory Elements, Transcriptional; Review; RNA Processing, Post-Transcriptional; RNA-binding protein; RNA-protein interactions; systems biology; Transcription, Genetic; translation; DNA microarray; systems biology; translation; RNA-binding protein; Post-transcriptional gene regulation

Post-transcriptional regulation of gene expression plays important roles in diverse cellular processes such as development, metabolism and cancer progression. Whereas many classical studies explored the mechanistics and physiological impact on specific mRNA substrates, the recent development of geno...