Development of an indirect ELISA for detecting Toxoplasma gondii IgG antibodies based on a recombinant TgIMP1 protein

• Published in: PLoS neglected tropical diseases Vol. 18; no. 8; p. e0012421
• Main Authors: Dong, Hongjie, Zhang, Junmei, Wang, Qi, Shen, Yanmei, Zhou, Beibei, Dai, Lisha, Zhu, Wenju, Sun, Hang, Xie, Xiaoman, Xie, Huanhuan, Xu, Chao, Zhao, Guihua, Yin, Kun
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 14.08.2024; Public Library of Science (PLoS)
• Subjects: Analysis; Animals; Antibodies, Protozoan - blood; Antigens, Protozoan - genetics; Antigens, Protozoan - immunology; Biology and Life Sciences; Care and treatment; Diagnosis; Dosage and administration; Engineering and Technology; Enzyme-linked immunosorbent assay; Enzyme-Linked Immunosorbent Assay - methods; Escherichia coli - genetics; Humans; Immunoglobulin G; Immunoglobulin G - blood; Medicine and Health Sciences; Physical Sciences; Protozoan Proteins - genetics; Protozoan Proteins - immunology; Recombinant proteins; Recombinant Proteins - genetics; Recombinant Proteins - immunology; Research and Analysis Methods; Risk factors; Sensitivity and Specificity; Toxoplasma - genetics; Toxoplasma - immunology; Toxoplasmosis; Toxoplasmosis - diagnosis; Toxoplasmosis - immunology; Toxoplasmosis - parasitology; China

Toxoplasma gondii ( T . gondii ) is widely spread around the world, which can cause serious harm to immunosuppressed patients. Currently, the commercial test kits are poor at assessing T . gondii infection and vaccine effectiveness, making an urgent need to exploit effective enzyme-linked immunosorb...