Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description

• Published in: Clinical infectious diseases Vol. 59; no. 9; pp. 1225 - 1233
• Main Authors: Al-Abdallat, Mohammad Mousa, Payne, Daniel C., Alqasrawi, Sultan, Rha, Brian, Tohme, Rania A., Abedi, Glen R., Al Nsour, Mohannad, Iblan, Ibrahim, Jarour, Najwa, Farag, Noha H., Haddadin, Aktham, Al-Sanouri, Tarek, Tamin, Azaibi, Harcourt, Jennifer L., Kuhar, David T., Swerdlow, David L., Erdman, Dean D., Pallansch, Mark A., Haynes, Lia M., Gerber, Susan I.
• Format: Journal Article
• Language: English
• Published: United States OXFORD UNIVERSITY PRESS 01.11.2014; Oxford University Press
• Subjects: Adult; and Commentaries; Antibodies; Antibodies, Viral - blood; ARTICLES AND COMMENTARIES; Coronavirus; Coronavirus Infections - diagnosis; Coronavirus Infections - epidemiology; Coronavirus Infections - immunology; Coronavirus Infections - prevention & control; Cough; Cross Infection - diagnosis; Cross Infection - epidemiology; Cross Infection - immunology; Cross Infection - prevention & control; Disease outbreaks; Disease Outbreaks - statistics & numerical data; Dyspnea; Editor's Choice; Enzyme linked immunosorbent assay; Epidemics; Epidemiology; Female; Health care industry; Health Personnel; Hospitals; Humans; Infections; Jordan - epidemiology; Male; Middle Aged; Middle East Respiratory Syndrome Coronavirus - immunology; Nosocomial infections; Polymerase chain reaction; Respiratory diseases; Seroepidemiologic Studies; Viruses; Jordan; Jordan (country); novel coronavirus; MERS-CoV; Jordan; seroepidemiology; Middle East respiratory syndrome

Background. In April 2012, the Jordan Ministry of Health investigated an outbreak of lower respiratory illnesses at a hospital in Jordan; 2 fatal cases were retrospectively confirmed by real-time reverse transcription polymerase chain reaction (rRT-PCR) to be the first detected cases of Middle East...