Diurnal rhythm and stress regulate dendritic architecture and spine density of pyramidal neurons in the rat infralimbic cortex

• Published in: Behavioural brain research Vol. 205; no. 2; pp. 406 - 413
• Main Authors: Perez-Cruz, Claudia, Simon, Mária, Flügge, Gabriele, Fuchs, Eberhard, Czéh, Boldizsár
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier B.V 28.12.2009; Elsevier
• Subjects: Animals; Behavioral psychophysiology; Biological and medical sciences; Body Weight - physiology; Chronic stress; Circadian Rhythm - physiology; Dendrite; Dendrites - physiology; Dendritic Spines - physiology; Diurnal changes; Fundamental and applied biological sciences. Psychology; Immobilization; Male; Medial prefrontal cortex; Neuronal Plasticity - physiology; Neurons - cytology; Neurons - physiology; Photoperiod; Prefrontal Cortex - cytology; Prefrontal Cortex - physiology; Prefrontal Cortex - physiopathology; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Pyramidal Cells - cytology; Pyramidal Cells - physiology; Pyramidal Cells - physiopathology; Rats; Rats, Sprague-Dawley; Restraint, Physical - adverse effects; Stress, Psychological - physiopathology; Time Factors; Wakefulness - physiology; Immobilization; Medial prefrontal cortex; Chronic stress; Diurnal changes; Dendrite; Architecture; Rat; Rodentia; Biological rhythm; Circadian rhythm; Diurnal variation; Density; Stress; Vertebrata; Chronic; Mammalia; Animal; Dendritic spine; Pyramidal neuron

The medial prefrontal cortex (mPFC) participates in several higher order cognitive functions and is involved in the regulation of the stress response. The infralimbic cortex (ILC), the most ventral part of the mPFC, receives a strong afferent input from the master circadian pacemaker, the suprachias...