Epigenetically dysregulated genes and pathways implicated in the pathogenesis of non-syndromic high myopia

• Published in: Scientific reports Vol. 9; no. 1; p. 4145
• Main Authors: Vishweswaraiah, Sangeetha, Swierkowska, Joanna, Ratnamala, Uppala, Mishra, Nitish K., Guda, Chittibabu, Chettiar, Shiva S., Johar, Kaid R., Mrugacz, Malgorzata, Karolak, Justyna A., Gajecka, Marzena, Radhakrishna, Uppala
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 11.03.2019; Nature Publishing Group
• Subjects: 45/61; 631/208/176/1988; 692/308/53/2423; Child; Child, Preschool; CpG Islands; DNA Methylation; Epigenesis, Genetic; Female; Gene Regulatory Networks; Genetics; Genomes; Humanities and Social Sciences; Humans; Male; Minority & ethnic groups; multidisciplinary; Myopia; Myopia - genetics; Myopia - pathology; Public health; Science; Science (multidisciplinary)

Myopia, commonly referred to as nearsightedness, is one of the most common causes of visual disability throughout the world. It affects more people worldwide than any other chronic visual impairment condition. Although the prevalence varies among various ethnic groups, the incidence of myopia is inc...