Adipose-derived mesenchymal stem cells preserve cardiac function via ANT-1 in dilated cardiomyopathy hamster model

• Published in: Regenerative therapy Vol. 18; pp. 182 - 190
• Main Authors: Mori, Daisuke, Miyagawa, Shigeru, Kido, Takashi, Hata, Hiroki, Ueno, Takayoshi, Toda, Koichi, Kuratani, Toru, Oota, Miwa, Kawai, Kotoe, Kurata, Hayato, Nishida, Hiroyuki, Sawa, Yoshiki
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.12.2021; Japanese Society for Regenerative Medicine; Elsevier
• Subjects: ATP; Idiopathic dilated cardiomyopathy; Mesenchymal stem cells; Mitochondrial transporter; Original; EF; HGF; VEGF; LV; Mitochondrial transporter; ADSC; ANOVA; OD; TGFR; SEM; ATP; Mesenchymal stem cells; Idiopathic dilated cardiomyopathy

Idiopathic dilated cardiomyopathy (DCM) is associated with abnormalities in cytoskeletal proteins, mitochondrial ATP transporter, microvasculature, and fibrosis. Mesenchymal stem cells (MSCs) can ameliorate distressed mitochondrial and structural proteins, as well as fibrosis, via the paracrine effe...