Identification and elimination of replication-competent adeno-associated virus (AAV) that can arise by nonhomologous recombination during AAV vector production

• Published in: Journal of Virology Vol. 71; no. 9; pp. 6816 - 6822
• Main Authors: Allen, J M, Debelak, D J, Reynolds, T C, Miller, A D
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.09.1997
• Subjects: adeno-associated virus; Animals; Capsid - genetics; Cell Line, Transformed; Cytomegalovirus - genetics; Dependovirus - genetics; Dependovirus - isolation & purification; Dependovirus - physiology; DNA-Binding Proteins - genetics; Genetic Vectors; Humans; Metallothionein - genetics; Mice; Recombination, Genetic; Transformation, Genetic; Tumor Cells, Cultured; Viral Proteins - genetics; Virus Replication

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