Hypercalcemia Associated with Extramammary Paget’s Disease

• Published in: Case reports in oncology Vol. 13; no. 3; pp. 1209 - 1214
• Main Authors: Sato, Tetsuko, Wada, Yoshihisa, Kamitani, Nobuhiko, Yamamoto, Takenobu, Aoyama, Yumi, Fujimoto, Wataru, Tanaka, Ryo
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.09.2020; Karger Publishers
• Subjects: Antigens; behavioral disturbance; Cancer therapies; Case Report; Case reports; Chemotherapy; extramammary paget’s disease; Fractures; Hypercalcemia; Kidney cancer; Ligands; Liver; Lymphatic system; Medical prognosis; Metastasis; parathyroid hormone-related protein; Pathogenesis; Patients; Hypercalcemia; Extramammary Paget’s disease; Behavioral disturbance; Parathyroid hormone-related protein

Hypercalcemia of malignancy occurs in up to one third of patients at some point during the course of their advanced stage. The majority of them is caused by humoral hypercalcemia of malignancy due to systemic secretion of parathyroid hormone–related protein (PTHrP) by tumor cells. Extramammary Paget...