Cardiac resident macrophages: Spatiotemporal distribution, development, physiological functions, and their translational potential on cardiac diseases

• Published in: Acta pharmaceutica Sinica. B Vol. 14; no. 4; pp. 1483 - 1493
• Main Authors: Jin, Jing, Wang, Yurou, Liu, Yueqin, Chakrabarti, Subrata, Su, Zhaoliang
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2024; Elsevier
• Subjects: Cardiac development; Cardiac homeostasis; Cardiac resident macrophages; Clinical translation; Physiological functions; Research tools; Review; Spatiotemporal distribution; Transcriptional characteristics; Cardiac resident macrophages; Clinical translation; Cardiac development; Research tools; Cardiac homeostasis; Transcriptional characteristics; Physiological functions; Spatiotemporal distribution

Cardiac resident macrophages (CRMs) are the main population of cardiac immune cells. The role of these cells in regeneration, functional remodeling, and repair after cardiac injury is always the focus of research. However, in recent years, their dynamic changes and contributions in physiological sta...