Mastoid obliteration and external auditory canal reconstruction using 3D printed bioactive glass S53P4 /polycaprolactone scaffold loaded with bone morphogenetic protein-2: A simulation clinical study in rabbits

• Published in: Regenerative therapy Vol. 21; pp. 469 - 476
• Main Authors: Yu, Fenghui, Fan, Xiaoxia, Wu, Hongxia, Ou, Yangxi, Zhao, Xuxu, Chen, Tao, Qian, Yi, Kang, Houyong
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.12.2022; Japanese Society for Regenerative Medicine; Elsevier
• Subjects: Bioactive glass S53P4; External auditory canal Reconstruction, 3D printing; Mastoid obliteration; Original; BMP2; CWDM; CWUM; CSD; Bioactive glass S53P4; PCL; External auditory canal Reconstruction, 3D printing; Mastoid obliteration; FDM; BMSCs; S53P4

The lack of good prosthetic materials and objective standards has limited the promotion of mastoid obliteration and external auditory canal reconstruction, and the quality of the surgery varies. In this study, bioactive glass S53P4 (S53P4), the most popular artificial prosthetic material, was modifi...