The Transforming Rho Family GTPase Wrch-1 Disrupts Epithelial Cell Tight Junctions and Epithelial Morphogenesis

• Published in: Molecular and Cellular Biology Vol. 29; no. 4; pp. 1035 - 1049
• Main Authors: Brady, Donita C., Alan, Jamie K., Madigan, James P., Fanning, Alan S., Cox, Adrienne D.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.02.2009; Taylor & Francis; American Society for Microbiology (ASM)
• Subjects: Actins - metabolism; Adaptor Proteins, Signal Transducing - metabolism; Animals; Cell Adhesion - drug effects; Cell Polarity - drug effects; Cell Proliferation - drug effects; Cell Shape - drug effects; Cercopithecus aethiops; COS Cells; Dogs; Enzyme Activation - drug effects; Epithelial Cells - cytology; Epithelial Cells - drug effects; Epithelial Cells - enzymology; Epithelium - drug effects; Epithelium - embryology; Epithelium - enzymology; Guanosine Triphosphate - pharmacology; Humans; Morphogenesis - drug effects; Mutation - genetics; Protein Binding - drug effects; Protein Structure, Tertiary; Protein Transport - drug effects; rho GTP-Binding Proteins - chemistry; rho GTP-Binding Proteins - metabolism; Tight Junctions - drug effects; Tight Junctions - enzymology

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