DNA Topoisomerase II Mutant of Saccharomyces cerevisiae: Topoisomerase II is Required for Segregation of Daughter Molecules at the Termination of DNA Replication
A temperature-sensitive DNA topoisomerase II mutant of the yeast Saccharomyces cerevisiae has been identified. Genetic analysis shows that a single recessive nuclear mutation is responsible for both temperature-sensitive growth and enzymatic activity. Thus, topoisomerase II is essential for viabilit...
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Published in | Proceedings of the National Academy of Sciences - PNAS Vol. 81; no. 9; pp. 2616 - 2620 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
National Academy of Sciences of the United States of America
01.05.1984
National Acad Sciences |
Subjects | |
Online Access | Get full text |
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