A negative Helicobacter pylori serology test is more reliable for exclusion of premalignant gastric conditions than a negative test for current H. pylori infection: a report on histology and H. pylori detection in the general adult population

• Published in: Scandinavian journal of gastroenterology Vol. 40; no. 3; p. 302
• Main Authors: Storskrubb, Tom, Aro, Pertti, Ronkainen, Jukka, Vieth, Michael, Stolte, Manfred, Wreiber, Karin, Engstrand, Lars, Nyhlin, Henry, Bolling-Sternevald, Elisabeth, Talley, Nicholas J, Agréus, Lars
• Format: Journal Article
• Language: English
• Published: England 01.02.2005
• Subjects: Adult; Aged; Aged, 80 and over; Antibodies, Bacterial - blood; Biopsy; Diagnosis, Differential; Endoscopy, Digestive System; Enzyme-Linked Immunosorbent Assay; Female; Gastric Mucosa - pathology; Gastritis, Atrophic - microbiology; Gastritis, Atrophic - pathology; Helicobacter Infections - microbiology; Helicobacter Infections - pathology; Helicobacter pylori - immunology; Humans; Male; Middle Aged; Population Surveillance; Precancerous Conditions - microbiology; Precancerous Conditions - pathology; Pyloric Antrum - pathology; Random Allocation; Reproducibility of Results; Retrospective Studies; Serologic Tests; Stomach Neoplasms - pathology; Surveys and Questionnaires; Sweden; Sweden

Corpus-dominant gastritis, gastric mucosal atrophy and intestinal metaplasia (IM) associated with Helicobacter pylori infection are all known potential risk markers for the development of gastric cancer. As the accuracy for finding cases at risk in the general population is unknown, we aimed to dete...