Development of a seroepidemiological tool for bat-borne and shrew-borne hantaviruses and its application using samples from Zambia

• Published in: PLoS neglected tropical diseases Vol. 18; no. 11; p. e0012669
• Main Authors: Sarii, Rakiiya Sikatarii, Kajihara, Masahiro, Wei, Zuoxing, Lokpathirage, Sithumini M. W., Muthusinghe, Devinda S., Mori-Kajihara, Akina, Changula, Katendi, Qiu, Yongjin, Ndebe, Joseph, Hang’ombe, Bernard M., Kikuchi, Fuka, Hayashi, Ai, Suzuki, Motoi, Kamiya, Hajime, Arai, Satoru, Takada, Ayato, Yoshimatsu, Kumiko
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 21.11.2024; Public Library of Science (PLoS)
• Subjects: Animals; Antibodies, Viral - blood; Antigens, Viral - immunology; Bats; Biology and Life Sciences; Chiroptera - virology; Chlorocebus aethiops; Cross Reactions; Evaluation; Hantavirus Infections - epidemiology; Hantavirus Infections - immunology; Hantavirus Infections - veterinary; Hantavirus Infections - virology; Hantaviruses; Health aspects; Humans; Medical research; Medicine and Health Sciences; Medicine, Experimental; Mice; Nucleocapsid Proteins - genetics; Nucleocapsid Proteins - immunology; Orthohantavirus - classification; Orthohantavirus - genetics; Orthohantavirus - immunology; Phylogeny; Research and Analysis Methods; Serodiagnosis; Seroepidemiologic Studies; Serologic Tests - methods; Shrews; Shrews - virology; Testing; Vero Cells; Zambia - epidemiology; Zambia; Japan

Rodent-borne orthohantaviruses are the causative agents of hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Apart from the classic rodent-borne hantaviruses, numerous species of hantaviruses have been identified in shrews and bats; however, their antigenicity and pathogenicit...