Radiographic osteoarthritis and pain are independent predictors of knee cartilage loss: a prospective study

• Published in: Internal medicine journal Vol. 42; no. 3; pp. 274 - 280
• Main Authors: Saunders, J., Ding, C., Cicuttini, F., Jones, G.
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Publishing Asia 01.03.2012
• Subjects: Aged; Arthralgia - etiology; Body Mass Index; cartilage; Cartilage, Articular - pathology; Comorbidity; Disease Progression; Female; Humans; Knee Joint - diagnostic imaging; Knee Joint - pathology; Magnetic Resonance Imaging; Male; Menisci, Tibial - pathology; Middle Aged; MRI; Obesity - epidemiology; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - diagnostic imaging; Osteoarthritis, Knee - epidemiology; Osteoarthritis, Knee - pathology; Osteophyte - complications; Osteophyte - diagnostic imaging; Pain Measurement; Prospective Studies; radiograph; Radiography; Risk Factors; Sampling Studies; Smoking - epidemiology; Surveys and Questionnaires; Tasmania - epidemiology; trial

Background:  There is controversy about whether pain and radiographic osteoarthritis (ROA) predict subsequent cartilage loss. The aim of this study was to describe the relationship between ROA, pain and cartilage loss in the knee. Methods:  We studied randomly selected subjects at baseline and appro...