The heterogeneity among subgroups of haplogroup J influencing Alzheimer’s disease risk

• Published in: Journal of advanced research Vol. 33; pp. 117 - 126
• Main Authors: Liu, HaoChen, Zhang, Yixuan, Zhao, Huimin, Du, Yanan, Liu, XiaoQuan
• Format: Journal Article
• Language: English
• Published: Egypt Elsevier B.V 01.11.2021; Elsevier
• Subjects: Alzheimer Disease - genetics; Alzheimer’s disease risk; DNA, Mitochondrial - genetics; Heterogeneity; Humans; Medicine; Mitochondrial haplogroups; Polymorphism, Single Nucleotide - genetics; Subgroup; Heterogeneity; Subgroup; Alzheimer’s disease risk; Mitochondrial haplogroups

[Display omitted] •There is heterogeneity among subgroups of haplogroup J which influences AD risk.•The heterogeneity among haplogroup J influences the MCI-to-AD conversion risk.•The heterogeneity among subgroups of haplogroup J is independent of Aβ and p-tau. The impact of mitochondrial haplogroups...