Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2 - Luo, Audrey; Jung, Jeesun; Longley, Martha; Rosoff, Daniel B.; Charlet, Katrin; Muench, Christine; Lee, Jisoo; Hodgkinson, Colin A.; Goldman, David; Horvath, Steve; Kaminsky, Zachary A.; Lohoff, Falk W. (Neuropsychopharmacology (New York, N.Y.), 2020)
Keywords: Adult; Age; Aging; Aging - blood; Aging - genetics; Alanine; Alanine transaminase; Alcohol use; Alcoholism - blood; Alcoholism - diagnosis; Alcoholism - genetics; Apolipoproteins; Apolipoproteins L - genetics; Body mass index; Cohort Studies; DNA methylation; DNA Methylation - genetics; Drinking behavior; Epigenesis, Genetic - genetics; Epigenetics; Female; Gene expression; Genetic diversity; Genetic Variation - genetics; Genome-wide association studies; Genome-Wide Association Study - methods; Genomes; Humans; Male; Middle Aged; Phenotypes; Quantitative trait loci; Single-nucleotide polymorphism; Systematic review; γ-Glutamyltransferase